Latest preprint reviews

  1. Beyond gradients: Factorized, geometric control of interference and generalization

    This article has 2 authors:
    1. Daniel N Scott
    2. Michael J Frank
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This valuable study introduces a novel method for controlling generalization and interference in neural networks undergoing continual learning. The authors provide solid evidence that their parsimonious method performs better than online gradient descent in several continual learning situations while providing biologically plausible links to three-factor learning rules. However, empirical validation is limited to linear networks, which raises questions about the generality of the results in non-linear networks. While the work is interesting to theoretical and experimental neuroscientists, improving the article presentation by clearly defining terminology before using it and providing more details on the setup of the simulation experiments would be vital to make the article more accessible.

    Reviewed by eLife

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
  2. Mid1 deletion leads to cognitive dysfunction in Opitz syndrome by regulates neural rhythms through the inhibition of p-Creb by PP2Ac

    This article has 9 authors:
    1. Ziye Yang
    2. Pengxiang Li
    3. Yue Chen
    4. Xiaoyu Guo
    5. Ping Liu
    6. Guangjian Ni
    7. Shuang Liu
    8. Liqun Chen
    9. Dong Ming
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This study provides important insights into the role of the Mid1 gene in hippocampal development and its implications in Opitz G/BBB syndrome, with much evidence supporting its impact on synaptic plasticity, neural rhythms, and cognitive functions. The methods, data, and analyses are solid, supporting the claims, presenting several minor weaknesses, and establishing Mid1 as a potential therapeutic target for neurological deficits associated with OS. The conclusions are largely supported by the results, but additional data are needed.

    Reviewed by eLife

    This article has 5 evaluationsAppears in 1 listLatest version Latest activity
Newer Page 198 of 869 Older