eLife

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1. We couldn't get details of this article at this time:
   10.1101/2024.12.30.630732

2. We couldn't get details of this article at this time:
   10.1101/2024.12.11.627879

3. We couldn't get details of this article at this time:
   10.1101/2024.11.24.625035

4. Bcl11b orchestrates subcerebral projection neuron axon development via cell-autonomous, non-cell-autonomous, and subcellular mechanisms

   This article has 7 authors:

   1. Yasuhiro Itoh
   2. Mollie B Woodworth
   3. Luciano C Greig
   4. Anne K Engmann
   5. Dustin E Tillman
   6. John J Hatch
   7. Jeffrey D Macklis

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This important contribution to the field demonstrates the role of a single transcription factor with cell-autonomous functions in the differentiation of two distinct neuronal populations in regulating the interactions between those cells in a non-autonomous manner to generate their final organized projection pattern. There are additional quantifications and controls that would enhance the study and would improve the strength of the evidence from incomplete if they were performed.

   Reviewed by eLife

5. Fast and slow synaptic plasticity enables concurrent control and learning

   This article has 2 authors:

   1. Brendan A Bicknell
   2. Peter E Latham

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This paper provides an important proposal for why learning can be much faster and more accurate if synapses have a fast component that immediately corrects errors, as well as a slower component that corrects behavior averaged over a longer timescale. It is convincingly shown that integrating these two learning timescales improves performance compared to classical strategies, particularly in terms of robustness and generalization when learning new target signals. However, the biological plausibility and justification for the proposed rapid learning mechanism require further elaboration and supporting mechanistic examples.

   Reviewed by eLife

6. We couldn't get details of this article at this time:
   10.1101/2023.12.07.570712

7. Optogenetic control of Protein Kinase C-epsilon activity reveals its intrinsic signaling properties with spatiotemporal resolution

   This article has 17 authors:

   1. Qunxiang Ong
   2. Crystal Jing Yi Lim
   3. Yilie Liao
   4. Justin Tze-Yang Ng
   5. Ler Ting Rachel Lim
   6. Shernys Xuan Yi Koh
   7. Sher En Chan
   8. Pheobe Lee Yu Ying
   9. Huijun Lim
   10. Chen Rui Ye
   11. Loo Chien Wang
   12. Siok Ghee Ler
   13. Radoslaw M Sobota
   14. Yaw Sing Tan
   15. Gerald I Shulman
   16. Xiaoyong Yang
   17. Weiping Han

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This manuscript introduces Opto-PKCε, an optogenetic tool that enabled important findings derived from interactome and phosphoproteome studies. Light-dependent recruitment of Opto-PKCε to the plasma membrane revealed the specific phosphorylation of the insulin receptor at Thr 1160. In turn, recruitment to mitochondria led to phosphorylation of the complex I subunit NDUFS4, correlating with reduced spare respiratory capacity. The evidence supporting these conclusions is solid, although additional clarification on data analysis would further enhance readability.

   Reviewed by eLife

8. We couldn't get details of this article at this time:
   10.1101/2024.11.27.625713

9. We couldn't get details of this article at this time:
   10.1101/2024.11.25.625193

10. We couldn't get details of this article at this time:
    10.1101/2024.08.02.606358