eLife

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1. We couldn't get details of this article at this time:
   10.1101/2025.03.18.643933

2. We couldn't get details of this article at this time:
   10.1101/2022.07.01.22277112

3. Somatic hypermutation patterns in immunoglobulin variable regions are established independently of the local transcriptional landscape

   This article has 15 authors:

   1. Ursula E Schoeberl
   2. Johanna Fitz
   3. Kimon Froussios
   4. Renan Valieris
   5. Iordanis Ourailidis
   6. Marina Makharova
   7. Bernd Bauer
   8. Tobias Neumann
   9. Eva-Maria Wiedemann
   10. Monika Steininger
   11. Adriana Cantoran Garcia
   12. Marialaura Mastrovito
   13. Hugo Mouquet
   14. Israel Tojal Da Silva
   15. Rushad Pavri

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This study clarifies that stalled RNA pol II is not sufficient for AID targeting, which is important to the field. The authors provide solid experimental evidence that RNA poll II stalling is not the driving mechanism for AID targeting, and even though the results are generally "negative", they are highly relevant to our current understanding of SHM. The authors propose premature transcription termination as a possible mechanism to determine V gene mutability, but the study does not experimentally address such possibilities. This paper makes investigators rethink the model with which AID finds single-strand DNA in the genome.

   Reviewed by eLife

4. We couldn't get details of this article at this time:
   10.1101/2025.03.26.645421

5. We couldn't get details of this article at this time:
   10.1101/2025.03.09.642211

6. We couldn't get details of this article at this time:
   10.1101/2025.01.21.633922

7. We couldn't get details of this article at this time:
   10.1101/2025.02.06.636916

8. We couldn't get details of this article at this time:
   10.1101/2025.01.26.634923

9. We couldn't get details of this article at this time:
   10.1101/2023.12.13.571356

10. Atherosclerosis, Intracranial Aneurysms, and Intermediate Biomarkers: Real-World Observational and Mendelian Randomization Research

    This article has 10 authors:

    1. Wei Liu
    2. Zhaoxu Zheng
    3. Chenglong Liu
    4. Yuanren Zhai
    5. Shuang Wang
    6. Liangran Huang
    7. Rong Wang
    8. Yan Zhang
    9. Peicong Ge
    10. Dong Zhang

    This article has been curated by 1 group:

    • Curated by eLife

      eLife Assessment

      This is valuable work with theoretical implications for possible mediation by MMP12 in the link between atherosclerosis and intracranial aneurysms, using Mendelian Randomization for causal inference. Additional analysis would be required to verify the claims, which currently have incomplete support in terms of the strength of evidence. Given that most of the identified causal associations do not hold after correcting for multiple tests, the conclusions should be carefully reviewed in order to be fully supported by the results.

    Reviewed by eLife