eLife

Latest preprint reviews

1. FGF and MafB regulated cadherin expression drives lamina formation in the auditory hindbrain

   This article has 6 authors:

   1. Rosanna CG Smith
   2. Maryam Clark
   3. Mireya Vazquez-Prada
   4. Marc Astick
   5. Kristina C Tubby
   6. Stephen R Price

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     The authors conducted a valuable study that investigates a molecular pathway mediating the transformation of a cell aggregate into a sheet known as the nucleus laminaris, a crucial site for auditory processing. While the study offers a comprehensive view of the sequence of developmental events and suggests possible roles for FGF signaling, the transcription factor Mafb, and the cell surface adhesive molecule Cadherin-23 in this process, the current data were considered incomplete.

   Reviewed by eLife

2. We couldn't get details of this article at this time:
   10.1101/2025.04.23.650151

3. We couldn't get details of this article at this time:
   10.1101/2025.01.21.634027

4. We couldn't get details of this article at this time:
   10.1101/2024.06.05.597468

5. We couldn't get details of this article at this time:
   10.1101/2025.02.05.636581

6. We couldn't get details of this article at this time:
   10.1101/2024.11.29.626007

7. Coenzyme A governs proinflammatory macrophage metabolism

   This article has 13 authors:

   1. Greg. A Timblin
   2. Kevin. M Tharp
   3. Johanna ten Hoeve
   4. Daniel S Kantner
   5. Ilayda Baydemir
   6. Eric A Noel
   7. Chandra Khantwal
   8. Pankaj K Singh
   9. Joshua N Farahzad
   10. Jorge Domínguez-Andrés
   11. Russell E Vance
   12. Nathaniel W Snyder
   13. Valerie M Weaver

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This important study looks into the effect of exogenous CoA on the response of TLR4-activated macrophages. Specifically, CoA enhances the LPS response by examining metabolomics, 13C tracing, and assessments of transcription and acetylation. Together, these provide a compelling series of findings that show exogenous CoA is taken up by macrophages, and this facilitates histone acetylation and transcription associated with activation and antimicrobial activity.

   Reviewed by eLife

8. We couldn't get details of this article at this time:
   10.1101/2025.05.02.651885

9. Midbrain somatostatin-expressing cells control pain-suppression during defensive states

   This article has 14 authors:

   1. Nanci Winke
   2. Frank Aby
   3. Daniel Jercog
   4. Coline Riffault
   5. Rabia Bouali-Benazzouz
   6. Juliette Viellard
   7. Delphine Girard
   8. Zoé Grivet
   9. Marc Landry
   10. Laia Castell
   11. Emmanuel Valjent
   12. Stephane Valerio
   13. Pascal Fossat
   14. Cyril Herry

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This important study shows that long-range somatostatin-expressing neurons in the ventrolateral periaqueductal grey that project to the rostral ventromedial medulla selectively suppress pain responses during conditioned fear. The evidence supporting these conclusions is exceptional, with methods spanning a novel cued fear-conditioned analgesia paradigm, cell-type-specific optogenetic activation and inhibition, anatomical circuit tracing, and in vivo spinal cord electrophysiology. These results will be of broad interest to systems and behavioral neuroscientists studying fear, pain, and descending pain-control circuitry.

   Reviewed by eLife

10. We couldn't get details of this article at this time:
    10.1101/2025.04.15.648920