eLife

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1. AGES for Ageing: Evaluating the auxin-inducible gene expression system for use in Drosophila ageing studies

   This article has 4 authors:

   1. Taylor McGilvary
   2. Kriti Gupta
   3. Adam J. Dobson
   4. Nathan Woodling

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This study provides useful information for the Drosophila ageing community by characterising the auxin-based gene expression system (AGES) and identifying important caveats associated with its use in adult flies. The authors provide solid evidence for sex-, age-, tissue- and dose-dependent variability in transgene induction, as well as effects of auxin feeding and AGES activation on stress resistance, metabolism, and lifespan. While the study would benefit from a broader characterisation of some of these limitations, the findings provide a helpful benchmark for researchers using AGES in ageing studies.

   Reviewed by eLife

2. We couldn't get details of this article at this time:
   10.1101/2025.07.11.664439

3. We couldn't get details of this article at this time:
   10.64898/2026.06.12.731854

4. We couldn't get details of this article at this time:
   10.64898/2026.07.15.738260

5. We couldn't get details of this article at this time:
   10.64898/2025.12.12.693832

6. We couldn't get details of this article at this time:
   10.1101/2025.07.18.665446

7. We couldn't get details of this article at this time:
   10.64898/2026.05.28.727987

8. We couldn't get details of this article at this time:
   10.64898/2026.07.03.731744

9. We couldn't get details of this article at this time:
   10.64898/2026.06.24.734260

10. We couldn't get details of this article at this time:
    10.64898/2026.05.27.728115