eLife

Latest preprint reviews

1. AGES for Ageing: Evaluating the auxin-inducible gene expression system for use in Drosophila ageing studies

   This article has 4 authors:

   1. Taylor McGilvary
   2. Kriti Gupta
   3. Adam J. Dobson
   4. Nathan Woodling

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This study provides useful information for the Drosophila ageing community by characterising the auxin-based gene expression system (AGES) and identifying important caveats associated with its use in adult flies. The authors provide solid evidence for sex-, age-, tissue- and dose-dependent variability in transgene induction, as well as effects of auxin feeding and AGES activation on stress resistance, metabolism, and lifespan. While the study would benefit from a broader characterisation of some of these limitations, the findings provide a helpful benchmark for researchers using AGES in ageing studies.

   Reviewed by eLife

2. Crossmodal representations in the auditory cortex of deaf and hearing individuals

   This article has 13 authors:

   1. Barbara Manini
   2. Konstantin Grin
   3. Martin Eimer
   4. Samuel Evans
   5. Luigi Tamè
   6. Bencie Woll
   7. Rita Bertani
   8. Dilay Ercelik
   9. Lucy Core
   10. Yueming Gao
   11. Matthew Longo
   12. Valeria Vinogradova
   13. Velia Cardin

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This study offers valuable insights into brain responses to somatosensory and visual temporal and spatial tasks in the auditory cortex of Deaf and hearing individuals. The evidence for a sensorily-bound representation in the deprived cortex -- rather than abstract -- is solid; however, the study will benefit from some additional analyses to better clarify and contextualise the results. This work will be of broad interest to neuroscientists investigating brain plasticity and development.

   Reviewed by eLife

3. GPCR-mediated regulation of glial TNF production

   This article has 4 authors:

   1. Zahra Abbasi
   2. Shirin Sadighparvar
   3. Marie Franquin
   4. David Stellwagen

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This study presents a useful finding on using diverse experimental systems to understand how neuromodulatory signals shape glial inflammatory signaling; however, the strength of evidence is inadequate. The astrocyte-enrichment method used may permit contamination by microglia, oligodendrocyte-lineage cells, or neurons, complicating attribution of TNF expression specifically to astrocytes. This concern is compounded by the strong microglial response to Gi manipulation and the lack of quantitative validation of chemogenetic cell-type specificity in vivo. These weaknesses have hindered further evaluation of the claims.

   Reviewed by eLife

4. We couldn't get details of this article at this time:
   10.64898/2026.07.15.738260

5. We couldn't get details of this article at this time:
   10.64898/2025.12.12.693832

6. We couldn't get details of this article at this time:
   10.1101/2025.07.18.665446

7. We couldn't get details of this article at this time:
   10.64898/2026.05.28.727987

8. We couldn't get details of this article at this time:
   10.64898/2026.07.03.731744

9. We couldn't get details of this article at this time:
   10.64898/2026.06.24.734260

10. We couldn't get details of this article at this time:
    10.64898/2026.05.27.728115