eLife

Latest preprint reviews

1. Error-driven representation learning in the mesolimbic system

   This article has 4 authors:

   1. George Cai
   2. Max F. Scheller
   3. Wolfgang Kelsch
   4. Samuel J. Gershman

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This important study presents compelling evidence for dopamine-based representation learning in the mouse olfactory tubercle. While this work suggests that gradient descent in deep networks serves as a helpful framework for understanding neural representations, the empirical evidence provided remains incomplete. Nonetheless, this work will be of significant interest to systems and computational neuroscientists, cognitive scientists, and machine learning theorists.

   Reviewed by eLife

2. Comprehensive lipidomics of tissue macrophages reveal LTE4–driven eosinophil survival

   This article has 15 authors:

   1. Magdalena A. Czubala
   2. Patricia Rodrigues
   3. Natacha Ipseiz
   4. Marcela Rosas
   5. Sandra Dimonte
   6. Iestyn Pope
   7. Christine Hinz
   8. Dina Fathalla
   9. Jorge Alvarez-Jarreta
   10. Victoria J. Tyrrell
   11. Wolfgang Langbein
   12. Paola Borri
   13. Robert Andrews
   14. Valerie B. O’Donnell
   15. Philip R. Taylor

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This is an important study that provides evidence that GATA6-dependent programming of peritoneal macrophages helps to regulate lipid metabolism and influences eosinophil survival. The evidence linking GATA6 deficiency to altered lipid profiles and eosinophil accumulation is solid, although the proposed mechanistic pathway connecting sphingolipid remodelling, LTE4 production and eosinophil survival currently remains incomplete. Strengthening these links and/or appropriately calming the conclusions would help to increase the impact of the study.

   Reviewed by eLife

3. Emergent particle collection by cyanobacteria through gliding motility and filament buckling

   This article has 6 authors:

   1. Rebecca N. Poon
   2. Kelsey Cremin
   3. Alberto Scarampi
   4. Mary Coates
   5. Albane Théry
   6. Orkun S. Soyer

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This manuscript presents important work on macrostructure formation in a freshwater filamentous cyanobacterium, focusing on its ability to aggregate and buckle. The authors employ a wide range of experiments and approaches, including time-lapse imaging and 3D theoretical modelling, to establish the physical dynamics of filaments, such as gliding motility and buckling. They demonstrate that, in addition to gliding motility, filament length and flexibility are essential for the ability of cyanobacteria to capture particles and form aggregates. Overall, the study provides convincing evidence and advances our understanding of the role of microbial motility in the environment. It will be of broad interest to biophysicists and environmental microbiologists.

   Reviewed by eLife

4. We couldn't get details of this article at this time:
   10.1101/2025.03.18.643888

5. We couldn't get details of this article at this time:
   10.64898/2026.07.13.738215

6. We couldn't get details of this article at this time:
   10.64898/2026.03.10.710929

7. We couldn't get details of this article at this time:
   10.64898/2026.06.26.734916

8. Lactylation of Influenza Virus Polymerase Acidic Protein Promotes Viral Replication and Pathogenicity

   This article has 14 authors:

   1. Shaoyu Tu
   2. Yue Du
   3. Wei Liang
   4. Xiaoyi Xu
   5. Jiahui Zou
   6. Yuchao Yang
   7. Chuhan Xiong
   8. Yanglin Li
   9. Meijun Jiang
   10. Aotian Ouyang
   11. Tong Chen
   12. Meilin Jin
   13. Huanchun Chen
   14. Hongbo Zhou

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This valuable study reveals a role for lactylation in influenza polymerase function and virus replication. The evidence supporting the claims is solid, although the direct involvement of ATAT1 and SIRT1 in this modification and the functional relevance of the identified sites can be further substantiated. These findings will appeal broadly to influenza virologists studying polymerase regulation, as well as researchers investigating the functional roles of lactylation.

   Reviewed by eLife

9. We couldn't get details of this article at this time:
   10.64898/2026.07.01.735787

10. We couldn't get details of this article at this time:
    10.64898/2026.06.01.729383