eLife

Latest preprint reviews

1. Bcl11b dose-dependently regulates positive selection of CD8 T cells to the virtual memory fate

   This article has 2 authors:

   1. Tom Sidwell
   2. Ellen V Rothenberg

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     The study provides important insight into the development of CD8 T cell virtual memory cells by identifying a dose-sensitive role for Bcl11b. The authors define the developmental stages affected by reduced Bcl11b expression and establish its role in promoting the virtual memory fate. The evidence is compelling, supported by multiple genetic models and complementary approaches.

   Reviewed by eLife

2. Phylogenetic Mosaic of an Arms Race with Asymmetrical Sexual Conflict and Its Macroevolutionary Consequences in a Lineage of Small Water Striders

   This article has 12 authors:

   1. Zihe Li
   2. Huanyu Chen
   3. Zezhong Jin
   4. Hendrik Freitag
   5. Christine Hecher
   6. Herbert Zettel
   7. Siying Fu
   8. Chen Liu
   9. Mu Qiao
   10. Boxiong Guo
   11. Wenjun Bu
   12. Zhen Ye

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This valuable study explores the phylogeny and macroevolutionary patterns of water striders, linking sexual conflict-driven morphological traits to species diversification. It provides robust and compelling evidence for incomplete lineage sorting (ILS), introgression, and differential evolutionary rates of male and female antagonistic traits, offering valuable insights into sexual conflict and speciation.

   Reviewed by eLife

3. Cutaneous inflammation accelerates the premalignant expansion of melanocytes bearing oncogenic mutations

   This article has 9 authors:

   1. Diana Tran
   2. Anastasiia Vaska
   3. Tyler El Rayes
   4. Natalie Lovinger
   5. Yassmin A. Elbanna
   6. Esther Lee
   7. Christin E. Burd
   8. Jonathan H. Zippin
   9. Morgan Huse

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This is an important work, using preclinical models and reporting that a shared inflammatory and vascular leakage response following Treg depletion, UVB irradiation, and DNFB contact hypersensitivity facilitates outgrowth of premalignant melanocytes. However, some of the work to support the claims is incomplete; this pertains particularly to the quantification of melanocyte expansion and sample size inconsistencies. With some additional supporting evidence to strengthen the claims, the study will be of broad interest to cancer biologists and immunologists.

   Reviewed by eLife

4. Genomic analysis of Klebsiella pneumoniae causing community-acquired respiratory deaths among Zambian infants and children using targeted RNA-probe hybridization-capture metagenomics

   This article has 28 authors:

   1. Kenneth Lindstedt
   2. Alyse Wheelock
   3. Mulemba Samutela
   4. Wasifa Kabir
   5. Mwelwa Chasaya
   6. Natasha Namuziya
   7. Emilia Jumbe Marsden
   8. Monica Kapasa
   9. Chibamba Mumba
   10. Bwalya Mulenga
   11. Lisa Nkole
   12. Rachel Pieciak
   13. Victor Mudenda
   14. Chilufya Chikoti
   15. Benard Ngoma
   16. Charles Chimoga
   17. Sarah Chirwa
   18. Lilian Pemba
   19. Diana Nzara
   20. James Lungu
   21. Leah Forman
   22. Edgar Simulundu
   23. William MacLeod
   24. Crispin Moyo
   25. Somwe Wa Somwe
   26. Kathryn E. Holt
   27. Arnfinn Sundsfjord
   28. Christopher J. Gill

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This useful study reports the application of targeted RNA-probe hybridization-capture metagenomic sequencing to characterize Klebsiella pneumoniae detected in post-mortem lung tissue from infants and young children who died from respiratory illness in Lusaka, Zambia. The findings provide a convincing proof-of-concept for the use of targeted sequencing to recover clinically relevant genomic information from archived post-mortem tissue specimens. However, the evidence supporting broader epidemiological and public health conclusions should be interpreted with caution given the small number of cases, the limitations inherent to culture-independent sequencing, and the fact that the study was not designed to determine the source or setting of acquisition.

   Reviewed by eLife

5. We couldn't get details of this article at this time:
   10.64898/2026.07.01.735788

6. We couldn't get details of this article at this time:
   10.64898/2026.06.17.26354096

7. We couldn't get details of this article at this time:
   10.64898/2026.02.11.705448

8. Supervised Domain Adaptation Mitigates Cross-Ethnicity Prediction Error in Neuroimaging-Based Cognitive Prediction

   This article has 5 authors:

   1. Farzane Lal Khakpoor
   2. William van der Vliet
   3. Jeremiah Deng
   4. Yue Wang
   5. Narun Pat

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This study provides a useful investigation of machine learning approaches that can lessen potential gaps in the prediction of behaviour from brain imaging data across majority and minority samples. The authors provide incomplete evidence to suggest that domain adaptation methods can mitigate these gaps. The analysis would benefit from further testing of model generalisability and the inclusion of recommended workflows for how the tested approaches can be used in future research. This work will be of interest to scientists using machine learning in brain imaging.

   Reviewed by eLife

9. A molecular glue in plants: The lectin domain of LecRK-I.9 creates persistent plasma membrane - cell wall connections

   This article has 7 authors:

   1. Denise S. Arico
   2. Ugo Segura
   3. Annalisa Bellandi
   4. Claire Lionnet
   5. Marjolaine Martin
   6. Olivier Hamant
   7. Herve Canut

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     The cell wall and plasma membrane are tightly associated in plant cells, and even after plasmolysis, sites of strong contact remain between the plasma membrane and cell wall. Here, the authors provide solid data to implicate an Arabidopsis lectin-like receptor kinase in plasma-membrane-to-cell-wall contact sites, and propose that these attachment sites are of importance for plant resistance to hyperosmotic stress, yet the evidence remains incomplete without key controls. These important results broaden our view on dynamic modulation of plasma membrane topology and its physiological consequences.

   Reviewed by eLife

10. We couldn't get details of this article at this time:
    10.64898/2026.06.26.734820