Latest preprint reviews

  1. Domain-general computational integration in the Sense of Agency

    This article has 5 authors:
    1. Amir Harduf
    2. Ophir Netzer
    3. Oz Mashiah
    4. Adam Zaidel
    5. Roy Salomon
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This important study examines how temporal and spatial discrepancies between an action and its visual feedback are combined in judgments related to the sense of agency. Using a virtual-reality reaching task and computational modeling, the authors show that both discrepancies influence self-attribution and that a multiplicative model outperforms the prespecified alternatives, a result reproduced in a preregistered replication. The evidence is convincing for the conclusion that temporal and spatial information is integrated. Other models - beyond multiplication - may in principle account equally well for the observed data; sharpening these claims and situating the findings more clearly within Bayesian accounts of cue integration would further strengthen this key contribution.

    Reviewed by eLife

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
  2. A Sterol-Binding Cavity Underlies Sterol Recognition and Differential Activation of the ABCG5/G8

    This article has 9 authors:
    1. Fatemeh Rezaei
    2. Isra F. Omar
    3. Danny Farhat
    4. Zi-Wen Weng
    5. Kadambari Vijay Sai
    6. Qing-Fang Xiao
    7. Yuan-Chih Chang
    8. Shang-Te Danny Hsu
    9. Jyh-Yeuan Lee
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This work presents valuable findings that identify ergosterol binding by the human ABC transporter ABCG5/G8 and show that ergosterol stimulates its ATPase activity more strongly than cholesterol, advancing understanding of sterol recognition and transport. The evidence from single-particle cryo-EM, molecular dynamics simulations, and biochemical assays is convincing and solid, although additional structures and mutational studies would strengthen the proposed mechanism. These results provide key insight into the molecular basis of sterol recognition and regulation of ABCG5/G8 and will be of interest to researchers studying sterol transport and ABC transporter function.

    Reviewed by eLife

    This article has 5 evaluationsAppears in 1 listLatest version Latest activity
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