eLife

Latest preprint reviews

1. Whole human organ clearing and multimodal mapping

   This article has 10 authors:

   1. Héloïse Policet-Bétend
   2. Tomàs Jordà-Siquier
   3. Geraldine Cuenu
   4. Maeva Badré
   5. Sami Schranz
   6. Julien Da Costa
   7. Céline Brockmann
   8. Pascal Senn
   9. Daniel Huber
   10. Christophe M Lamy

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This important paper introduces a generalisable tissue-clearing method to study human anatomy and the organisation of complex tissues and organs. The evidence for its broad applicability is compelling, based on results from 15 diverse human tissues, including highly heterogeneous specimens, with successful labelling using five antibodies and five fluorescent dyes. The method has broad potential applications across multiple disciplines.

   Reviewed by eLife

2. Structures of LolB bound to LolA or lipoprotein resolve the final steps of bacterial lipoprotein trafficking

   This article has 4 authors:

   1. Abigail E. Jepson
   2. Elise Kaplan
   3. Nicholas P. Greene
   4. Vassilis Koronakis

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This is a valuable study that aims to resolve the mechanistic details of the final steps of bacterial lipoprotein trafficking. The evidence supporting the conclusions is solid but incomplete. This work will be of interest to biochemists and microbiologists studying the bacterial cell envelope and those aiming to develop novel antibacterial molecules.

   Reviewed by eLife

3. Sequence adaptations satisfy the constraints of mitochondrial membrane protein evolution

   This article has 8 authors:

   1. Tarun Yadav
   2. Jonathan H. Borowsky
   3. Alvaro Jesus Narbona-Perez
   4. Bhavya Soni
   5. Corey N. Cunningham
   6. James Carrington
   7. Michael Grabe
   8. Jared Rutter

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This important study provides theoretical and experimental evidence that aliphatic-to-threonine substitutions in transmembrane domains improve the translocation properties of mitochondrial proteins from the cytosol to mitochondria. The authors provide convincing evidence that substitutions within hydrophobic transmembrane regions of mitochondrial proteins may have contributed to their evolutionary adaptation following the transfer of their genes from the mitochondria to the nucleus. This study will be of interest to biologists and biochemists working on mitochondrial protein import and mitochondrial evolution.

   Reviewed by eLife

4. Spatiotemporal Dissociation of Human Amygdala Response to Negative Affect

   This article has 4 authors:

   1. Ke Bo
   2. Martin A. Lindquist
   3. Peter J. Gianaros
   4. Tor D. Wager

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This study provides valuable new insights into the functional differentiation of human amygdala subnuclei during the observation of negative images and emotional reappraisal. The evidence is convincing, particularly regarding differences in the time course of evoked responses and their partial correspondence with broad anatomical subdivisions. The work will be of interest to researchers studying the amygdala, emotional processing, and emotion regulation.

   Reviewed by eLife

5. We couldn't get details of this article at this time:
   10.64898/2026.07.13.738197

6. We couldn't get details of this article at this time:
   10.64898/2026.08.11.744217

7. We couldn't get details of this article at this time:
   10.1101/2025.11.25.690375

8. We couldn't get details of this article at this time:
   10.64898/2026.05.06.723165

9. We couldn't get details of this article at this time:
   10.1101/2025.11.13.688216

10. We couldn't get details of this article at this time:
    10.64898/2026.07.13.737774