Latest preprint reviews

  1. Connectomic Analysis of Mitochondria in the Central Brain of Drosophila

    This article has 18 authors:
    1. Kit D. Longden
    2. Patricia K. Rivlin
    3. Michał Januszewski
    4. Erika Neace
    5. Louis K. Scheffer
    6. Christopher Ordish
    7. Jody Clements
    8. Elliott Phillips
    9. Natalie Smith
    10. Satoko Takemura
    11. Lowell Umayam
    12. Claire Walsh
    13. Emily A. Yakal
    14. Timothy F. Musial
    15. Michael J. Devine
    16. Michael B. Reiser
    17. Stephen M. Plaza
    18. Stuart Berg
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This study provides a valuable resource describing the size, density, and synaptic proximity of mitochondria across thousands of neurons in the Drosophila brain, drawn from a well-annotated electron microscopy dataset. The evidence supporting the main descriptive findings is mostly solid, though some measured parameters contain internal inconsistencies and the proposed links between mitochondrial properties and neural activity or energy use remain speculative. The work will interest neuroscientists studying mitochondrial biology, energetics, and connectomics, and lays a foundation for future studies connecting mitochondrial organization to neural circuit function.

    Reviewed by eLife

    This article has 6 evaluationsAppears in 1 listLatest version Latest activity
  2. High-dimensional Characterization of Genome–Environment Fitness Landscapes in Klebsiella pneumoniae

    This article has 15 authors:
    1. Ge Zhou
    2. Georgia Williams
    3. Mathew T. Millner
    4. Raneem AlHirayban
    5. Wejdan Alosaimi
    6. Omniya Fallatah
    7. Adam J Hart
    8. Mohammed Malaikah
    9. Sara Iftikhar
    10. Huda Ahmad
    11. Mohammad Roghanian
    12. Ville Mustonen
    13. Rfeef AlYami
    14. Manuel Banzhaf
    15. Danesh Moradigaravand
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This study provides a valuable mapping of how genomic variation from a large collection of Klebsiella pneumoniae clinical isolates shapes bacterial fitness across 214 conditions. Solid data describe that fitness is strongly condition-dependent and that features can be advantageous under selection. Though the predictive, plasmid causality and GWAS association findings would be further strengthened by additional analyses ruling out population-structure confounding, these findings are of value for our understanding of the power of genotype to predict phenotype for this important human pathogen.

    Reviewed by eLife

    This article has 3 evaluationsAppears in 1 listLatest version Latest activity
  3. Thermotaxis behavior of Drosophila melanogaster : A quantitative analysis of sensory-motor integration and heat avoidance

    This article has 5 authors:
    1. Zeinab Moradi
    2. Sara Jahedazad
    3. Ehsan Hosseinian
    4. Tayebeh Minaei
    5. Ali Sadighi
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This study utilizes a two-choice assay to examine how groups of Drosophila melanogaster respond to temperature changes. The findings are useful, offering focused importance for the collective decision-making community. However, the strength of the evidence is incomplete, as the current data only partially support the primary claims and the work lacks the necessary integration into the existing literature to contextualize the findings.

    Reviewed by eLife

    This article has 5 evaluationsAppears in 1 listLatest version Latest activity
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