Latest preprint reviews

  1. Mapping abstraction and metacognition onto distinct transdiagnostic symptom profiles

    This article has 7 authors:
    1. Taiki Oka
    2. Yoshihiko Kunisato
    3. Kotaro Koizumi
    4. Misa Murakami
    5. Hugo Six
    6. Jessica E Taylor
    7. Aurelio Cortese
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This valuable study examines how abstraction and metacognition relate to transdiagnostic dimensions of psychopathology. It combines a reward-learning task, computational modelling and a large questionnaire. The evidence linking reduced metacognitive sensitivity to a compulsive hypersensitivity dimension is solid, but the evidence for the abstraction findings is currently incomplete. This work will be of interest to researchers studying metacognition and computational approaches to psychiatry.

    Reviewed by eLife

    This article has 5 evaluationsAppears in 1 listLatest version Latest activity
  2. Supervised Domain Adaptation Mitigates Cross-Ethnicity Prediction Error in Neuroimaging-Based Cognitive Prediction

    This article has 5 authors:
    1. Farzane Lal Khakpoor
    2. William van der Vliet
    3. Jeremiah Deng
    4. Yue Wang
    5. Narun Pat
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This study provides a useful investigation of machine learning approaches that can lessen potential gaps in the prediction of behaviour from brain imaging data across majority and minority samples. The authors provide incomplete evidence to suggest that domain adaptation methods can mitigate these gaps. The analysis would benefit from further testing of model generalisability and the inclusion of recommended workflows for how the tested approaches can be used in future research. This work will be of interest to scientists using machine learning in brain imaging.

    Reviewed by eLife

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
  3. A molecular glue in plants: The lectin domain of LecRK-I.9 creates persistent plasma membrane - cell wall connections

    This article has 7 authors:
    1. Denise S. Arico
    2. Ugo Segura
    3. Annalisa Bellandi
    4. Claire Lionnet
    5. Marjolaine Martin
    6. Olivier Hamant
    7. Herve Canut
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      The cell wall and plasma membrane are tightly associated in plant cells, and even after plasmolysis, sites of strong contact remain between the plasma membrane and cell wall. Here, the authors provide solid data to implicate an Arabidopsis lectin-like receptor kinase in plasma-membrane-to-cell-wall contact sites, and propose that these attachment sites are of importance for plant resistance to hyperosmotic stress, yet the evidence remains incomplete without key controls. These important results broaden our view on dynamic modulation of plasma membrane topology and its physiological consequences.

    Reviewed by eLife

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
  4. Reprogrammed peptidoglycan elongation reveals plasticity in bacterial growth modes

    This article has 3 authors:
    1. Carolina Basurto De Santiago
    2. Isabella S. Lin
    3. Beiyan Nan
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This paper demonstrates that relocating the MreB-Rod complex to the poles of E. coli can reprogram cell-wall synthesis, causing cells to elongate through peptidoglycan incorporation at the poles rather than along the cell length. This is a valuable finding for understanding how bacterial growth can be spatially reprogrammed and provides insight into how distinct modes of bacterial growth might arise. However, the evidence is currently incomplete, particularly regarding the nature of the polar structures, their relationship to cell shape and growth, and the requirement for a pre-existing pole.

    Reviewed by eLife

    This article has 5 evaluationsAppears in 1 listLatest version Latest activity
  5. WNK-SPAK/OSR1 signaling pathway facilitates ictal activity via reduced neuronal chloride extrusion rate

    This article has 7 authors:
    1. Volodymyr I. Dzhala
    2. Fu Hung Shiu
    3. Negah Rahmati
    4. Aloe Carroll
    5. Reagan Bae
    6. Kristopher T. Kahle
    7. Kevin J Staley
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This study presents a valuable investigation of how inhibition of the WNK-SPAK/OSR1 pathway influences neuronal chloride homeostasis and seizure-like activity in organotypic hippocampal slice cultures. The evidence supporting the principal mechanistic conclusions is incomplete because several proposed mechanisms are inferred from changes in chloride dynamics rather than directly demonstrated. The work will be of interest to researchers studying chloride homeostasis, inhibitory neurotransmission, and epilepsy.

    Reviewed by eLife

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
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