Latest preprint reviews

  1. Virtual reality reveals fine-scale alterations in behaviour following loss of the ADHD-linked gene adgrl3.1 in zebrafish

    This article has 5 authors:
    1. Phoebe Reynolds
    2. Emily Read
    3. Caitlin Daly-East
    4. Matthew O Parker
    5. Robert Hindges
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      The study presents valuable findings on early behavioral phenotypes that arise in an ADHD-associated adgrl3.1 mutant zebrafish, using a new behavioral approach with a closed-loop OMR assay. The evidence supporting the claims of the authors is solid; however, the validation of the method and analysis is incomplete and would benefit from more rigorous approaches and validation practices. This work will be of broad interest to developmental biologists and behavioral neuroscientists.

    Reviewed by eLife

    This article has 5 evaluationsAppears in 1 listLatest version Latest activity
  2. Flexible brain state engagement predicts cognitive control transdiagnostically

    This article has 14 authors:
    1. Jean Ye
    2. Saloni Mehta
    3. Milana Khaitova
    4. Jagriti Arora
    5. Fuyuze Tokoglu
    6. C Alice Hahn
    7. Cheryl Lacadie
    8. Abigail S Greene
    9. Marisa N Spann
    10. Gerard Sanacora
    11. Scott W Woods
    12. Vinod H Srihari
    13. R Todd Constable
    14. Dustin Scheinost
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This valuable paper reports on a measure of flexible brain state engagement, derived from fMRI, as a predictor of cognitive control. One strength of the study is the use of external datasets for validation and replication. The results are solid, although some may benefit from further explanation.

    Reviewed by eLife

    This article has 3 evaluationsAppears in 1 listLatest version Latest activity
  3. Rapid cortical reorganization tracks goal-directed sensorimotor learning in real time

    This article has 8 authors:
    1. Anthony Renard
    2. Georgios Foustoukos
    3. Maya Iuga
    4. Pol Bech
    5. Axel Bisi
    6. Robin F Dard
    7. Sylvain Crochet
    8. Carl CH Petersen
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This valuable study aimed to explore whether sensory representations in the cortex reorganize on the same timescale over which behavioral changes first emerge. Convincing evidence is presented to show that reward-dependent plasticity takes place in the mouse barrel cortex within a single recording session as mice learn a whisker detection task. However, the evidence supporting the authors' proposal that this rapid reorganization may involve spontaneous reactivation of neurons that gain stimulus responsiveness during training is incomplete. The work will be of interest to systems neuroscientists studying cortical circuits and learning.

    Reviewed by eLife

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
  4. Split-trial analysis reveals the information capacity of neural population codes

    This article has 2 authors:
    1. Dylan Le
    2. Xue-Xin Wei
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This valuable study describes a simple and robust approach for estimating information-limiting noise by splitting neural populations and comparing estimator values. The authors report more accurate and robust results compared to previous methods. The evidence for the robustness of the method is currently incomplete; some concerns regarding bias need to be resolved, and additional tests need to be provided on how the number of trials and neurons affect performance.

    Reviewed by eLife

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
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