Arcadia Science

Latest preprint reviews

1. A benchmark for large language models in bioinformatics

   This article has 10 authors:

   1. Varuni Sarwal
   2. Gaia Andreoletti
   3. Viorel Munteanu
   4. Ariel Suhodolschi
   5. Dumitru Ciorba
   6. Viorel Bostan
   7. Mihai Dimian
   8. Eleazar Eskin
   9. Wei Wang
   10. Serghei Mangul

   Reviewed by Arcadia Science

2. Development of a sensor for disulfide bond formation in diverse bacteria

   This article has 4 authors:

   1. Jocelyne Mendoza
   2. Dyotima
   3. Sally Abulaila
   4. Cristina Landeta

   Reviewed by Arcadia Science

3. Single-cell eQTL mapping in yeast reveals a tradeoff between growth and reproduction

   This article has 8 authors:

   1. James Boocock
   2. Noah Alexander
   3. Leslie Alamo Tapia
   4. Laura Walter-McNeill
   5. Shivani Prashant Patel
   6. Chetan Munugala
   7. Joshua S Bloom
   8. Leonid Kruglyak

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     This manuscript describes the mapping of natural DNA sequence variants that affect gene expression and its noise, as well as cell cycle timing, using as input single-cell RNA-sequencing of progeny from crosses between wild yeast strains. The method represents an important advance in the study of natural genetic variation. The findings, especially given the follow-up validation of the phenotypic impact of a mapped locus of major effect, provide convincing support for the rigor and utility of the method.

   Reviewed by eLife, Arcadia Science

4. RamanSPy: An Open-Source Python Package for Integrative Raman Spectroscopy Data Analysis

   This article has 6 authors:

   1. Dimitar Georgiev
   2. Simon Vilms Pedersen
   3. Ruoxiao Xie
   4. Álvaro Fernández-Galiana
   5. Molly M. Stevens
   6. Mauricio Barahona

   Reviewed by Arcadia Science

5. Technical upgrade of an open-source liquid handler to support bacterial colony screening

   This article has 5 authors:

   1. Irene del Olmo
   2. Pablo Yubero
   3. Álvaro Gómez-Luengo
   4. Juan Nogales
   5. David R. Espeso

   Reviewed by Arcadia Science

6. Functional annotation hypothetical proteins: a world to be explored in drug development in Trypanosomatids

   This article has 3 authors:

   1. Raissa Santos de Lima
   2. Ana Carolina Silva Bulla
   3. Manuela Leal da Silva

   Reviewed by Arcadia Science

7. Nanos2+ cells give rise to germline and somatic lineages in the sea anemone Nematostella vectensis

   This article has 8 authors:

   1. Andreas Denner
   2. Julia Steger
   3. Alexander Ries
   4. Elizaveta Morozova-Link
   5. Josefine Ritter
   6. Franziska Haas
   7. Alison G. Cole
   8. Ulrich Technau

   Reviewed by Arcadia Science

8. Beyond blast: enabling microbiologists to better extract literature, taxonomic distributions and gene neighbourhood information for protein families

   This article has 8 authors:

   1. Colbie J. Reed
   2. Rémi Denise
   3. Jacob Hourihan
   4. Jill Babor
   5. Marshall Jaroch
   6. Maria Martinelli
   7. Geoffrey Hutinet
   8. Valérie de Crécy-Lagard

   Reviewed by Arcadia Science

9. Novel Association of Lyme disease, Age, and Atopic Dermatitis

   This article has 17 authors:

   1. Brandon T. Lee
   2. Sarah D. Galloway
   3. Qingying Feng
   4. Satu Strausz
   5. Maia Shoham
   6. Paige Hansen
   7. Laughing Bear Torrez Dulgeroff
   8. Grace Blacker
   9. Ying Y. Yiu
   10. Paul Mansfield
   11. FinnGen
   12. Atif Saleem
   13. Eric Gars
   14. Erin C. Sanders
   15. Irving L. Weissman
   16. Hanna M. Ollila
   17. Michal Caspi Tal

   Reviewed by Arcadia Science

10. Alternative splicing across the tree of life

    This article has 4 authors:

    1. Rebeca de la Fuente
    2. Wladimiro Dı́az-Villanueva
    3. Vicente Arnau
    4. Andres Moya

    This article has been curated by 1 group:

    • Curated by eLife

      eLife Assessment

      The authors examined the frequency of alternative splicing across prokaryotes and eukaryotes and found that the rate of alternative splicing varies with taxonomic groups and genome coding content. This solid work, based on nearly 1,500 high-quality genome assemblies, relies on a novel genome-scale metric that enables cross-species comparisons and that quantifies the extent to which coding sequences generate multiple mRNA transcripts via alternative splicing. This timely study provides an important basis for improving our general understanding of genome architecture and the evolution of life forms.

    Reviewed by eLife, Arcadia Science