Mimicking opioid analgesia in cortical pain circuits
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Abstract
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Thus, we infer that the decades’ prior use of translationally non-relevant, high-doses of morphine in rodents was likely selected and optimized to modify reflexive detection metrics that are not reflective of the human pain experience and do not assess the effect of morphine on pain affective-evaluative dimensions
Interesting and important inference! Have you considered using your setup to do dose response tests for morphine?
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