Latest preprint reviews

1. BioLLMBench: A Comprehensive Benchmarking of Large Language Models in Bioinformatics

   This article has 7 authors:

   1. Varuni Sarwal
   2. Viorel Munteanu
   3. Timur Suhodolschi
   4. Dumitru Ciorba
   5. Eleazar Eskin
   6. Wei Wang
   7. Serghei Mangul

   Reviewed by Arcadia Science

2. Development of a sensor for disulfide bond formation in diverse bacteria

   This article has 4 authors:

   1. Jocelyne Mendoza
   2. Dyotima
   3. Sally Abulaila
   4. Cristina Landeta

   Reviewed by Arcadia Science

3. Single-cell eQTL mapping in yeast reveals a tradeoff between growth and reproduction

   This article has 8 authors:

   1. James Boocock
   2. Noah Alexander
   3. Leslie Alamo Tapia
   4. Laura Walter-McNeill
   5. Shivani Prashant Patel
   6. Chetan Munugala
   7. Joshua S Bloom
   8. Leonid Kruglyak

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     This manuscript describes the mapping of natural DNA sequence variants that affect gene expression and its noise, as well as cell cycle timing, using as input single-cell RNA-sequencing of progeny from crosses between wild yeast strains. The method represents an important advance in the study of natural genetic variation. The findings, especially given the follow-up validation of the phenotypic impact of a mapped locus of major effect, provide convincing support for the rigor and utility of the method.

   Reviewed by eLife, Arcadia Science

4. RamanSPy : An open-source Python package for integrative Raman spectroscopy data analysis

   This article has 6 authors:

   1. Dimitar Georgiev
   2. Simon Vilms Pedersen
   3. Ruoxiao Xie
   4. Álvaro Fernández-Galiana
   5. Molly M. Stevens
   6. Mauricio Barahona

   Reviewed by Arcadia Science

5. Technical upgrade of an open-source liquid handler to support bacterial colony screening

   This article has 5 authors:

   1. Irene del Olmo
   2. Pablo Yubero
   3. Álvaro Gómez-Luengo
   4. Juan Nogales
   5. David R. Espeso

   Reviewed by Arcadia Science

6. Functional annotation hypothetical proteins: a world to be explored in drug development in Trypanosomatids

   This article has 3 authors:

   1. Raissa Santos de Lima
   2. Ana Carolina Silva Bulla
   3. Manuela Leal da Silva

   Reviewed by Arcadia Science

7. Nanos2+ cells give rise to germline and somatic lineages in the sea anemone Nematostella vectensis

   This article has 8 authors:

   1. Andreas Denner
   2. Julia Steger
   3. Alexander Ries
   4. Elizaveta Morozova-Link
   5. Josefine Ritter
   6. Franziska Haas
   7. Alison G. Cole
   8. Ulrich Technau

   Reviewed by Arcadia Science

8. Beyond blast: enabling microbiologists to better extract literature, taxonomic distributions and gene neighbourhood information for protein families

   This article has 8 authors:

   1. Colbie J. Reed
   2. Rémi Denise
   3. Jacob Hourihan
   4. Jill Babor
   5. Marshall Jaroch
   6. Maria Martinelli
   7. Geoffrey Hutinet
   8. Valérie de Crécy-Lagard

   Reviewed by Arcadia Science

9. Novel Association of Lyme disease, Age, and Atopic Dermatitis

   This article has 17 authors:

   1. Brandon T. Lee
   2. Sarah D. Galloway
   3. Qingying Feng
   4. Satu Strausz
   5. Maia Shoham
   6. Paige Hansen
   7. Laughing Bear Torrez Dulgeroff
   8. Grace Blacker
   9. Ying Y. Yiu
   10. Paul Mansfield
   11. FinnGen
   12. Atif Saleem
   13. Eric Gars
   14. Erin C. Sanders
   15. Irving L. Weissman
   16. Hanna M. Ollila
   17. Michal Caspi Tal

   Reviewed by Arcadia Science

10. Evolutionary trends of alternative splicing

    This article has 4 authors:

    1. Rebeca de la Fuente
    2. Wladimiro Díaz-Villanueva
    3. Vicente Arnau
    4. Andrés Moya

    This article has been curated by 1 group:

    • Curated by eLife

      eLife assessment

      The authors examined whether the frequency of alternative splicing across entire genomes correlates with measures of complexities across prokaryotes and eukaryotes. Although the question is very interesting and important for our general understanding of the evolution of life forms, the work is inadequate: the methods, data, and analyses do not support the primary claims. The measure of alternative splicing frequency used by the authors is problematic; the method is inappropriate; the observed correlations may also be explained by known population genetics principles; and parts of the manuscript are difficult to understand.

    Reviewed by Arcadia Science, eLife