Systems Biology

Stool Dynamics and the Developing Gut Microbiome During Infancy

1. Mohammed Al-Andoli
2. Sarah Schoch
3. Andjela Markovic
4. Christophe Mühlematter
5. Matthieu Beaugrand
6. Oskar G. Jenni
7. Rabia Liamlahi
8. Jean-Claude Walser
9. Dennis Nielsen
10. Salome Kurth

Reviewed by Arcadia Science

Single-Cell Network Analysis Identifies CLEC4E as a Key Mediator of Proinflammatory mDC Responses in Influenza Infection

1. Subin Cho
2. Gabriel Laghlali
3. Arturo Marin
4. Adolfo García-Sastre
5. Gagandeep Singh
6. Michael Schotsaert
7. Won-Min Song
8. Christian V. Forst

Reviewed by preLights

Regulation of Transcriptional Bursting and Spatial Patterning in Early Drosophila Embryo Development

1. César Nieto
2. Zahra Vahdat
3. Bomyi Lim
4. Abhyudai Singh

• Curated by eLife

  eLife Assessment

  This study presents a valuable quantitative framework for analyzing transcription dynamics data for enhancers and genes expressed in the early Drosophila embryo. By analyzing existing data across both synthetic reporters and an endogenous gene (eve), this work provides evidence that spatial gene expression patterns within the embryo are largely determined by "activity time" - the time during which a gene is bursting. The methods and evidence are solid and should be of broad interest to researchers in developmental biology and quantitative gene regulation, but the study would be significantly enhanced by clarifying the novelty of the findings relative to prior work and presenting a rigorous benchmarking of their algorithm against previously used algorithms.

Reviewed by eLife

Multi-omics analysis of endothelial cells reveals the metabolic diversity that underlies endothelial cell functions

1. Stephan Durot
2. Peter F. Doubleday
3. Lydia Schulla
4. Amélie Sabine
5. Tatiana V. Petrova
6. Nicola Zamboni

Reviewed by Review Commons

Raman spectra identify vancomycin-resistant phenotypes and their transcriptomic features in Staphylococcus aureus

1. Ken-ichiro F. Kamei
2. Reiko Okura
3. Koseki J. Kobayashi-Kirschvink
4. Yuki Katayama
5. Yuichi Wakamoto

Reviewed by Arcadia Science

A push-pull system of repressors matches levels of glucose transporters to extracellular glucose in budding yeast

1. Luis Fernando Montaño-Gutierrez
2. Marc Sturrock
3. Iseabail Farquhar
4. Kevin Correia
5. Vahid Shahrezaei
6. Peter S. Swain

Reviewed by Review Commons