Pharmacology and Toxicology

  1. Effects of Hydroxychloroquine and Azithromycin on iPSC-derived Cardiomyocytes: Considerations for the Treatment of COVID-19 Patients

    1. Wener Li
    2. Xiaojing Luo
    3. Mareike S. Poetsch
    4. Reinhard Oertel
    5. Kapil Nichani
    6. Martin Schneider
    7. Anna Strano
    8. Marcel Hasse
    9. Robert-Patrick Steiner
    10. Lukas Cyganek
    11. Karina Hettwer
    12. Steffen Uhlig
    13. Kirsten Simon
    14. Kaomei Guan
    15. Mario Schubert

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  2. Broad-Spectrum In Vitro Antiviral Activity of ODBG-P-RVn: An Orally-Available, Lipid-Modified Monophosphate Prodrug of Remdesivir Parent Nucleoside (GS-441524)

    1. Michael K. Lo
    2. Punya Shrivastava-Ranjan
    3. Payel Chatterjee
    4. Mike Flint
    5. James R. Beadle
    6. Nadejda Valiaeva
    7. Joyce Murphy
    8. Robert T. Schooley
    9. Karl Y. Hostetler
    10. Joel M. Montgomery
    11. Christina F. Spiropoulou

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  3. The pH Dependence of Niclosamide Solubility, Dissolution, and Morphology: Motivation for Potentially Universal Mucin-Penetrating Nasal and Throat Sprays for COVID19, its Variants and other Viral Infections

    1. David Needham

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  4. Standardized Extract of Asparagus officinalis Stem Attenuates SARS-CoV-2 Spike Protein-Induced IL-6 and IL-1β Production by Suppressing p44/42 MAPK and Akt Phosphorylation in Murine Primary Macrophages

    1. Ken Shirato
    2. Jun Takanari
    3. Takako Kizaki

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  5. Doxycycline Inhibition of a Pseudotyped Virus Transduction Does Not Translate to Inhibition of SARS-CoV-2 Infectivity

    1. Luisa Diomede
    2. Sara Baroni
    3. Ada De Luigi
    4. Arianna Piotti
    5. Jacopo Lucchetti
    6. Claudia Fracasso
    7. Luca Russo
    8. Valerio Bonaldo
    9. Nicolò Panini
    10. Federica Filippini
    11. Fabio Fiordaliso
    12. Alessandro Corbelli
    13. Marten Beeg
    14. Massimo Pizzato
    15. Francesca Caccuri
    16. Marco Gobbi
    17. Emiliano Biasini
    18. Arnaldo Caruso
    19. Mario Salmona

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  6. Combination of Antiviral Drugs to Inhibit SARS-CoV-2 Polymerase and Exonuclease as Potential COVID-19 Therapeutics

    1. Xuanting Wang
    2. Carolina Q. Sacramento
    3. Steffen Jockusch
    4. Otávio Augusto Chaves
    5. Chuanjuan Tao
    6. Natalia Fintelman-Rodrigues
    7. Minchen Chien
    8. Jairo R. Temerozo
    9. Xiaoxu Li
    10. Shiv Kumar
    11. Wei Xie
    12. Dinshaw J. Patel
    13. Cindy Meyer
    14. Aitor Garzia
    15. Thomas Tuschl
    16. Patrícia T. Bozza
    17. James J. Russo
    18. Thiago Moreno L. Souza
    19. Jingyue Ju

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  7. Drug-free nasal spray as a barrier against SARS-CoV-2 infection: safety and efficacy in human nasal airway epithelia

    1. Fabio Fais
    2. Reda Juskeviciene
    3. Veronica Francardo
    4. Stéphanie Mateos
    5. Samuel Constant
    6. Massimo Borelli
    7. Ilja P. Hohenfeld
    8. Thomas Meyer

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  8. Evaluation of intranasal nafamostat or camostat for SARS-CoV-2 chemoprophylaxis in Syrian golden hamsters

    1. M Neary
    2. H Box
    3. J Sharp
    4. L Tatham
    5. P Curley
    6. J Herriott
    7. E Kijak
    8. U Arshad
    9. JJ Hobson
    10. RKR Rajoli
    11. H Pertinez
    12. A Valentijn
    13. K Dhaliwal
    14. F McCaughan
    15. SP Rannard
    16. A Kipar
    17. JP Stewart
    18. A Owen

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  9. Preliminary nonclinical safety and immunogenicity of an rVSV-ΔG-SARS-CoV-2-S vaccine in mice, hamsters, rabbits and pigs

    1. Noa Madar-Balakirski
    2. Amir Rosner
    3. Sharon Melamed
    4. Boaz Politi
    5. Michal Steiner
    6. Hadas Tamir
    7. Yfat Yahalom-Ronen
    8. Elad Bar-David
    9. Amir Ben-Shmuel
    10. Assa Sittner
    11. Itai Glinert
    12. Shay Weiss
    13. Erez Bar-Haim
    14. Hila Cohen
    15. Uri Elia
    16. Hagit Achdout
    17. Noam Erez
    18. Shahar Rotem
    19. Shlomi Lazar
    20. Abraham Nyska
    21. Shmuel Yitzhaki
    22. Adi Beth-Din
    23. Haim Levy
    24. Nir Paran
    25. Tomer Israely
    26. Hadar Marcus

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  10. SARS-CoV-2 Nucleocapsid Protein TR-FRET Assay Amenable to High Throughput Screening

    1. Kirill Gorshkov
    2. Desarey Morales Vasquez
    3. Kevin Chiem
    4. Chengjin Ye
    5. Bruce Nguyen Tran
    6. Juan Carlos de la Torre
    7. Thomas Moran
    8. Catherine Z. Chen
    9. Luis Martinez-Sobrido
    10. Wei Zheng

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity
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