Pharmacology and Toxicology

  1. Discovery of Highly Potent Fusion Inhibitors with Potential Pan-Coronavirus Activity That Effectively Inhibit Major COVID-19 Variants of Concern (VOCs) in Pseudovirus-Based Assays

    1. Francesca Curreli
    2. Shahad Ahmed
    3. Sofia M. B. Victor
    4. Aleksandra Drelich
    5. Siva S. Panda
    6. Andrea Altieri
    7. Alexander V. Kurkin
    8. Chien-Te K. Tseng
    9. Christopher D. Hillyer
    10. Asim K. Debnath

    Reviewed by ScreenIT

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  2. Woodsmoke particulates alter expression of antiviral host response genes in human nasal epithelial cells infected with SARS-CoV-2 in a sex-dependent manner

    1. Stephanie A. Brocke
    2. Grant T. Billings
    3. Sharon Taft-Benz
    4. Neil E. Alexis
    5. Mark T. Heise
    6. Ilona Jaspers

    Reviewed by ScreenIT

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  3. A Vimentin-Targeting Oral Compound with Host-Directed Antiviral and Anti-Inflammatory Actions Addresses Multiple Features of COVID-19 and Related Diseases

    1. Zhizhen Li
    2. Jianping Wu
    3. Ji Zhou
    4. Baoshi Yuan
    5. Jiqiao Chen
    6. Wanchen Wu
    7. Lian Mo
    8. Zhipeng Qu
    9. Fei Zhou
    10. Yingying Dong
    11. Kai Huang
    12. Zhiwei Liu
    13. Tao Wang
    14. Deebie Symmes
    15. Jingliang Gu
    16. Eiketsu Sho
    17. Jingping Zhang
    18. Ruihuan Chen
    19. Ying Xu

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  4. Effects of Hydroxychloroquine and Azithromycin on iPSC-derived Cardiomyocytes: Considerations for the Treatment of COVID-19 Patients

    1. Wener Li
    2. Xiaojing Luo
    3. Mareike S. Poetsch
    4. Reinhard Oertel
    5. Kapil Nichani
    6. Martin Schneider
    7. Anna Strano
    8. Marcel Hasse
    9. Robert-Patrick Steiner
    10. Lukas Cyganek
    11. Karina Hettwer
    12. Steffen Uhlig
    13. Kirsten Simon
    14. Kaomei Guan
    15. Mario Schubert

    Reviewed by ScreenIT

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  5. Broad-Spectrum In Vitro Antiviral Activity of ODBG-P-RVn: An Orally-Available, Lipid-Modified Monophosphate Prodrug of Remdesivir Parent Nucleoside (GS-441524)

    1. Michael K. Lo
    2. Punya Shrivastava-Ranjan
    3. Payel Chatterjee
    4. Mike Flint
    5. James R. Beadle
    6. Nadejda Valiaeva
    7. Joyce Murphy
    8. Robert T. Schooley
    9. Karl Y. Hostetler
    10. Joel M. Montgomery
    11. Christina F. Spiropoulou

    Reviewed by ScreenIT

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  6. The pH Dependence of Niclosamide Solubility, Dissolution, and Morphology: Motivation for Potentially Universal Mucin-Penetrating Nasal and Throat Sprays for COVID19, its Variants and other Viral Infections

    1. David Needham

    Reviewed by ScreenIT

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  7. Standardized Extract of Asparagus officinalis Stem Attenuates SARS-CoV-2 Spike Protein-Induced IL-6 and IL-1β Production by Suppressing p44/42 MAPK and Akt Phosphorylation in Murine Primary Macrophages

    1. Ken Shirato
    2. Jun Takanari
    3. Takako Kizaki

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  8. Doxycycline Inhibition of a Pseudotyped Virus Transduction Does Not Translate to Inhibition of SARS-CoV-2 Infectivity

    1. Luisa Diomede
    2. Sara Baroni
    3. Ada De Luigi
    4. Arianna Piotti
    5. Jacopo Lucchetti
    6. Claudia Fracasso
    7. Luca Russo
    8. Valerio Bonaldo
    9. Nicolò Panini
    10. Federica Filippini
    11. Fabio Fiordaliso
    12. Alessandro Corbelli
    13. Marten Beeg
    14. Massimo Pizzato
    15. Francesca Caccuri
    16. Marco Gobbi
    17. Emiliano Biasini
    18. Arnaldo Caruso
    19. Mario Salmona

    Reviewed by ScreenIT

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  9. Combination of Antiviral Drugs to Inhibit SARS-CoV-2 Polymerase and Exonuclease as Potential COVID-19 Therapeutics

    1. Xuanting Wang
    2. Carolina Q. Sacramento
    3. Steffen Jockusch
    4. Otávio Augusto Chaves
    5. Chuanjuan Tao
    6. Natalia Fintelman-Rodrigues
    7. Minchen Chien
    8. Jairo R. Temerozo
    9. Xiaoxu Li
    10. Shiv Kumar
    11. Wei Xie
    12. Dinshaw J. Patel
    13. Cindy Meyer
    14. Aitor Garzia
    15. Thomas Tuschl
    16. Patrícia T. Bozza
    17. James J. Russo
    18. Thiago Moreno L. Souza
    19. Jingyue Ju

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  10. Drug-free nasal spray as a barrier against SARS-CoV-2 infection: safety and efficacy in human nasal airway epithelia

    1. Fabio Fais
    2. Reda Juskeviciene
    3. Veronica Francardo
    4. Stéphanie Mateos
    5. Samuel Constant
    6. Massimo Borelli
    7. Ilja P. Hohenfeld
    8. Thomas Meyer

    Reviewed by ScreenIT

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