Neuroscience | Sciety

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Input-specific gating of NMDA amplification via HCN channels in mouse L2/3 pyramidal neurons

This article has 4 authors:
1. Viktor János Oláh
2. Jing Wu
3. Leonard K Kaczmarek
4. Matthew JM Rowan
This article has been curated by 1 group:
- Curated by eLife
  
  eLife Assessment
  
  In this valuable study the authors use electrophysiology in brain slices and computer modeling and suggest that layer 2/3 pyramidal neurons of the mouse cortex have functional HCN channels on the proximal apical dendrite which allows distinct processing of input at that location from the input to distal apical dendrites. The revisions improved the solid paper but some of the concerns were not addressed sufficiently and many of these concerns could be addressed by further revision.
Reviewed by eLife

This article has 9 evaluationsAppears in 1 listLatest version Jan 15, 2025Latest activity Jan 13, 2025

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