Neuroscience

A gradual transition toward categorical representations along the visual hierarchy during working memory, but not perception

1. Chaipat Chunharas
2. Michael J Wolff
3. Meike D Hettwer
4. Rosanne L Rademaker

• Curated by eLife

  eLife Assessment

  This important study examined orientation representations along the visual hierarchy during perception and working memory. The authors provide results suggesting that during working memory there is a gradient where representations are more categorical in nature later in the visual hierarchy. The evidence presented is solid, most notably a match between behavioral data, though minor weakness can be attributed to the tasks and behaviors not being designed to address this question. The findings should be of interest to a relatively broad audience, namely those interested in the relationship between sensory coding and memory.

Reviewed by eLife

Plasma Membrane Remodelling in GM2 Gangliosidoses Drives Synaptic Dysfunction

1. Alex S. Nicholson
2. David A. Priestman
3. Robin Antrobus
4. James C. Williamson
5. Reuben Bush
6. Henry G. Barrow
7. Emily Smith
8. Kostantin Dobrenis
9. Nicholas A. Bright
10. Frances M. Platt
11. Janet E. Deane

Reviewed by Review Commons

Zebrafish live imaging reveals a surprisingly small percentage of spinal cord motor neurons die during early development

1. Hao Jia
2. Hongmei Yang
3. Kathy Qian Luo

• Curated by eLife

  eLife Assessment

  The authors have developed a biosensor for programmed cell death. They use this biosensor to provide cell death measurements in a specific early development time. The findings useful in a specific context; however, the application of this biosensor is incomplete as it does not take into account existing literature and is missing controls.

Reviewed by eLife