Neuroscience

Neurons in the medial prefrontal cortex are involved in spatial tuning and signaling upcoming choice independently from hippocampal sharp-wave ripples

1. Hanna den Bakker
2. Fabian Kloosterman

• Curated by eLife

  eLife Assessment

  This useful study reports analyses of Neuropixel recordings in the medial prefrontal cortex and hippocampus of rats in a spatial navigation trial, focusing on classifying prefrontal neurons based on SWR modulation and anatomical location. Reviewers were unconvinced by the presented evidence for the claim that distinct populations of mPFC neurons participate in non-local ensemble representations during SWR and non-SWR periods, and were unconvinced by the presented evidence for a previously unrecognized anatomical distinction between these populations. Further analyses might strengthen the incomplete evidence for some conclusions, and some of the strong claims of the paper should likely be moderated.

Reviewed by eLife

Responses to conflicting binocular stimuli in mouse primary visual cortex

1. Daniel P. Montgomery
2. Daniel A. Bowen
3. Jin Wu
4. Mark F. Bear
5. Eric D. Gaier

Reviewed by preLights

Asymmetric neural entrainment at resonance frequencies underlies unilateral spatial neglect

1. Yuka O Okazaki
2. Noriaki Hattori
3. Teiji Kawano
4. Megumi Hatakenaka
5. Ichiro Miyai
6. Keiichi Kitajo

• Curated by eLife

  eLife Assessment

  This valuable study uses EEG and computational modeling to investigate hemispheric oscillatory asymmetries in unilateral spatial neglect. The work benefits from rare patient data and a careful multimethod approach. However, the evidence is incomplete because key assumptions about alpha‑band entrainment and methodological confounds such as lesion variability and eye‑movement artifacts remain insufficiently addressed.

Reviewed by eLife

Where is the melody? Spontaneous attention orchestrates melody formation during polyphonic music listening

1. Martin M Winchester
2. Kevin Reynolds
3. Charbel Nebo
4. Ian Cecil Scott
5. Giovanni M Di Liberto

• Curated by eLife

  eLife Assessment

  This valuable work potentially advances our understanding of melody extraction in polyphonic music listening by identifying spontaneous attentional focus in uninstructed listening contexts. However, the evidence supporting the main conclusions is incomplete. The work will be of interest to psychologists and neuroscientists working on music listening, attention, and perception in ecological settings.

Reviewed by eLife

High-throughput single-cell CRISPRi screens stratify neurodevelopmental functions of schizophrenia-associated genes

1. Umut Yildiz
2. Annique Claringbould
3. Mikael Marttinen
4. Víctor Campos-Fornés
5. Mantha Lamprousi
6. Manu Saraswat
7. Mathias Saver
8. Daria Bunina
9. Michael W. Dorrity
10. Judith Zaugg
11. Kyung-Min Noh

Reviewed by preLights

Molecular and functional dissection using CaMPARI-seq reveals the neuronal organization for dissociating optic flow-dependent behaviors

1. Koji Matsuda
2. Chung-Han Wang
3. Hisaya Kakinuma
4. Atsushi Toyoda
5. Tomoya Shiraki
6. Koichi Kawakami
7. Fumi Kubo

Reviewed by preLights