Neuroscience

Pallium-encoded valence-specific chemosensory amplification of eye-body coordination in larval zebrafish

1. Samuel KH Sy
2. Danny CW Chan
3. Jenny J Zhang
4. Jing Lyu
5. Crystal Feng
6. Kui Wang
7. Vincent CT Mok
8. Kenneth KY Wong
9. Yu Mu
10. Yu Hu
11. Ho Ko

• Curated by eLife

  eLife Assessment

  Using their unique Fish-On-Chips optofluidics platform, the authors make three important findings: the presence of precise coupling between saccades and tail flips can be used to discriminate between turning or gliding behaviours; aversive and appetitive chemosensory cues differentially modulate these behaviours; transformation from cue valence to behaviour is encoded by the pallium. The evidence supporting these findings is solid. The work advances our understanding of the ancient interplay between chemosensation and motor output through the modulation of eye-body coordination.

Reviewed by eLife

Goal-directed visual information processing with GABAergic inhibition in parietal cortex

1. Zhiyan Wang
2. Sinah Wiborg
3. Antonia Wittmann
4. Nina Beck
5. Susanna Hirschle
6. Dominik Aschenbrenner
7. Markus Becker
8. Sebastian M Frank

• Curated by eLife

  eLife Assessment

  This important study employs functional magnetic resonance spectroscopy (fMRS) to demonstrate that GABAergic inhibition in the parietal cortex actively suppresses goal-irrelevant distractors, thereby facilitating goal-directed visual tracking. The data and analyses are solid, and the methodology is validated. However, the link between the metabolic changes and the purported functional mechanisms is incomplete due to concerns with experimental design and interpretations. The study will be of interest to researchers studying goal-directed behavior and neurochemical dynamics in cognitive processing.

Reviewed by eLife

The Good, the Bad, and the Ugly: Segmentation-Based Quality Control of Structural Magnetic Resonance Images

1. Robert Dahnke
2. Polona Kalc
3. Gabriel Ziegler
4. Julian Grosskreutz
5. Christian Gaser

Reviewed by GigaScience

Distributed neural computation and the evolution of the first brains

1. Vikram Chandra
2. Mehrana R. Nejad
3. Allison P. Kann
4. Ananya Salem
5. Karl A.P. Hill
6. Richard Schalek
7. Jeff Lichtman
8. L. Mahadevan
9. Mansi Srivastava

Reviewed by PREreview