Neuroscience

Systematic annotation of a complete adult male Drosophila nerve cord connectome reveals principles of functional organisation

1. Elizabeth C Marin
2. Billy J Morris
3. Tomke Stürner
4. Andrew S Champion
5. Dominik Krzeminski
6. Griffin Badalamente
7. Marina Gkantia
8. Christopher R Dunne
9. Katharina Eichler
10. Shin-ya Takemura
11. Imaan FM Tamimi
12. Siqi Fang
13. Sung Soo Moon
14. Han SJ Cheong
15. Feng Li
16. Philipp Schlegel
17. Sebastian E Ahnert
18. Stuart Berg
19. Janelia FlyEM Project Team
20. Gwyneth M Card
21. Marta Costa
22. David Shepherd
23. Gregory SXE Jefferis

• Curated by eLife

  eLife assessment

  This fundamental study provides a near-comprehensive anatomical description and annotation of neurons in a male Drosophila ventral nerve cord, based on large-scale circuit reconstruction from electron microscopy. This connectome resource will be of substantial interest to neuroscientists interested in sensorimotor control, neural development, and analysis of brain connectivity. However, although the evidence is extensive and compelling, the presentation of results in this very large manuscript lacks clarity and concision.

Reviewed by eLife

Effects of early life adversity and adolescent basolateral amygdala activity on corticolimbic connectivity and anxiety behaviors

1. Caitlyn R. Cody
2. Emilce Artur de la Villarmois
3. Anabel Miguelez Fernandez
4. Janelle Lardizabal
5. Chaney McKnight
6. Kuei Tseng
7. Heather C. Brenhouse

Reviewed by preLights

Nonlinear sensitivity to acoustic context is a stable feature of neuronal responses to complex sounds in auditory cortex of awake mice

1. Marios Akritas
2. Alex G Armstrong
3. Jules M Lebert
4. Arne F Meyer
5. Maneesh Sahani
6. Jennifer F Linden

• Curated by eLife

  eLife assessment

  This study provides important findings regarding the stability over time of the response properties of neurons in the auditory cortex, including their nonlinear sensitivity to sound context. The data obtained from chronic recordings combined with nonlinear stimulus-response estimation provide convincing evidence that auditory cortical representations are stable over a period of days to weeks. While this study should be of widespread interest to sensory neuroscientists, the paper would be strengthened by a more thorough assessment and discussion of the effects of context and of the stability of the responses, as well as by the inclusion of more information about the location and types of neurons that were sampled.

Reviewed by eLife