Neuroscience

  1. Synaptic Organization of Surface AMPARs Changes by Brain Region and Tauopathy

    1. Rohit M. Vaidya
    2. Jiahao Zhang
    3. Duncan Nall
    4. Rujuta Pendharkar
    5. Yongjae Lee
    6. Eung Chang Kim
    7. Donghan Ma
    8. Fang Huang
    9. Hiroshi Nonaka
    10. Shigeki Kiyonaka
    11. Itaru Hamachi
    12. Hee Jung Chung
    13. Paul R. Selvin

    • Curated by eLife

      eLife Assessment

      This is an important study that establishes a novel and enabling 3D super-resolution imaging approach for visualizing the nanoscale organization of AMPA receptors in thick mouse brain tissue. The biological findings are of importance and interest to the neuroscience field, with potential implications for neurodegenerative disease research. Some of the biological conclusions would benefit from strengthened quantitative analysis and revisions to the manuscript to ensure that the interpretations are appropriately aligned with what is supported by the analysis.

    Reviewed by eLife

    4 evaluationsAppears in 1 listLatest version Latest activity
Page 1 of 302 Next