Neurology

Hospitalisation for COVID-19 predicts long lasting cerebrovascular impairment: A prospective observational cohort study

1. Kamen A Tsvetanov
2. Lennart R B Spindler
3. Emmanuel A Stamatakis
4. Virginia FJ Newcombe
5. Victoria C Lupson
6. Doris A Chatfield
7. Anne E Manktelow
8. Joanne G Outtrim
9. Anne Elmer
10. Nathalie Kingston
11. John R Bradley
12. Edward T Bullmore
13. James B Rowe
14. David K Menon
15. The Cambridge NeuroCOVID Group
16. The NIHR COVID-19 BioResource
17. The Cambridge NIHR Clinical Research Facility
18. The CITIID-NIHR BioResource COVID-19 Collaboration

Reviewed by ScreenIT

Breakthrough SARS-CoV-2 infections in MS patients on disease-modifying therapies

1. Irene Schiavetti
2. Cinzia Cordioli
3. Maria Laura Stromillo
4. Maria Teresa Ferrò
5. Alice Laroni
6. Eleonora Cocco
7. Gaia Cola
8. Livia Pasquali
9. Maria Teresa Rilla
10. Elisabetta Signoriello
11. Rosa Iodice
12. Alessia Di Sapio
13. Roberta Lanzillo
14. Francesca Caleri
15. Pietro Annovazzi
16. Antonella Conte
17. Giuseppe Liberatore
18. Francesca Ruscica
19. Renato Docimo
20. Simona Bonavita
21. Monica Ulivelli
22. Paola Cavalla
23. Francesco Patti
24. Diana Ferraro
25. Marinella Clerico
26. Paolo Immovilli
27. Massimiliano Di Filippo
28. Marco Salvetti
29. Maria Pia Sormani

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Correlation between leukocyte phenotypes and prognosis of amyotrophic lateral sclerosis

1. Can Cui
2. Caroline Ingre
3. Li Yin
4. Xia Li
5. John Andersson
6. Christina Seitz
7. Nicolas Ruffin
8. Yudi Pawitan
9. Fredrik Piehl
10. Fang Fang

• Curated by eLife

  Evaluation Summary:

  Cui et al. colleagues carried out a longitudinal analysis of blood cell counts in a cohort of patients with ALS patients. They found increased numbers of neutrophils and monocytes that negatively correlated with ALSFRS-R score, but not with rate of disease progression. In addition, increased levels in NK and central memory TH2 T cells correlated with a lower risk of death, while increased levels of CD4 CD45RA effector memory and CD8 T cells were correlated with a higher risk of death. These findings have broad implications for ALS pathogenesis and the development of immune-based ALS therapies tailored to specific immune cell populations.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. The reviewers remained anonymous to the authors.)

Reviewed by eLife

Persistently reduced humoral and sustained cellular immune response from first to third SARS-CoV-2 mRNA vaccination in anti-CD20-treated multiple sclerosis patients

1. Hamza Mahmood Bajwa
2. Frederik Novak
3. Anna Christine Nilsson
4. Christian Nielsen
5. Dorte K. Holm
6. Kamilla Østergaard
7. Agnes Hauschultz Witt
8. Keld-Erik Byg
9. Isik S. Johansen
10. Kristen Mittl
11. William Rowles
12. Scott S. Zamvil
13. Riley Bove
14. Joseph J. Sabatino
15. Tobias Sejbaek

Reviewed by ScreenIT

Severe Acute Respiratory Syndrome Coronavirus 2 Third Vaccine Immune Response in Multiple Sclerosis Patients Treated with Ocrelizumab

1. Livnat Brill
2. Catarina Raposo
3. Ariel Rechtman
4. Omri Zveik
5. Netta Levin
6. Esther Oiknine‐Djian
7. Dana G. Wolf
8. Adi Vaknin‐Dembinsky

Reviewed by ScreenIT

Post-COVID-19 memory complaints: Prevalence and associated factors

1. M. Ahmed
2. S. Roy
3. M.A. Iktidar
4. S. Chowdhury
5. S. Akter
6. A.M.K. Islam
7. M.D.H. Hawlader

Reviewed by ScreenIT

Mapping dopaminergic projections in the human brain with resting-state fMRI

1. Marianne Oldehinkel
2. Alberto Llera
3. Myrthe Faber
4. Ismael Huertas
5. Jan K Buitelaar
6. Bastiaan R Bloem
7. Andre F Marquand
8. Rick C Helmich
9. Koen V Haak
10. Christian F Beckmann

• Curated by eLife

  Evaluation Summary:

  This paper provides a novel method for characterizing the functional topography of the striatum based on functional connectivity profiles. Importantly, a series of ambitious analyses provide compelling (if somewhat indirect) evidence via associations to SPECT imaging, in patient populations (Parkinson's Disease), and under drug manipulation (L-DOPA), that this organization is strongly associated with the distribution of dopamine transporter concentrations. Markers of dopamine neurophysiology and signaling, especially those available in standard, non-invasive imaging acquisitions, are of great interest across a wide number of research domains.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #1, Reviewer # 2 and Reviewer #3 agreed to share their name with the authors.)

Reviewed by eLife

Longitudinal prediction of motor dysfunction after stroke: a disconnectome study

1. Lilit Dulyan
2. Lia Talozzi
3. Valentina Pacella
4. Maurizio Corbetta
5. Stephanie J. Forkel
6. Michel Thiebaut de Schotten

Reviewed by PeerRef

Prognostic value of serum/plasma neurofilament light chain for COVID ‐19‐associated mortality

1. Ruturaj R. Masvekar
2. Peter Kosa
3. Kimberly Jin
4. Kerry Dobbs
5. Michael A. Stack
6. Riccardo Castagnoli
7. Virginia Quaresima
8. Helen C. Su
9. Luisa Imberti
10. Luigi D. Notarangelo
11. Bibiana Bielekova

Reviewed by ScreenIT

Cellular and Humoral Immunity to SARS‐CoV‐2 Infection in Multiple Sclerosis Patients on Ocrelizumab and Other Disease‐Modifying Therapies: A Multi‐Ethnic Observational Study

1. Ilya Kister
2. Yury Patskovsky
3. Ryan Curtin
4. Jinglan Pei
5. Katherine Perdomo
6. Zoe Rimler
7. Iryna Voloshyna
8. Marie I. Samanovic
9. Amber R. Cornelius
10. Yogambigai Velmurugu
11. Samantha Nyovanie
12. Joseph J. Kim
13. Ethan Tardio
14. Tamar E. Bacon
15. Lana Zhovtis Ryerson
16. Pranil Raut
17. Rosetta Pedotti
18. Kathleen Hawker
19. Catarina Raposo
20. Jessica Priest
21. Mark Cabatingan
22. Ryan C. Winger
23. Mark J. Mulligan
24. Michelle Krogsgaard
25. Gregg J. Silverman

Reviewed by ScreenIT