Microbiology

  1. SARS-CoV-2 Evolution and Patient Immunological History Shape the Breadth and Potency of Antibody-Mediated Immunity

    1. Maria Manali
    2. Laura A Bissett
    3. Julien A R Amat
    4. Nicola Logan
    5. Sam Scott
    6. Ellen C Hughes
    7. William T Harvey
    8. Richard Orton
    9. Emma C Thomson
    10. Rory N Gunson
    11. Mafalda Viana
    12. Brian Willett
    13. Pablo R Murcia

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  2. Reaction Conditions Promoting the Specific Detection of SARS-CoV-2 NendoU Enzymatic Activity

    1. Nodar Makharashvili
    2. James O. McNamara

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  3. SARS-CoV-2 Omicron subvariants evolved to promote further escape from MHC-I recognition

    1. Miyu Moriyama
    2. Carolina Lucas
    3. Valter Silva Monteiro
    4. Yale SARS-CoV-2 Genomic Surveillance Initiative
    5. Akiko Iwasaki

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  4. Neutralisation sensitivity of SARS-CoV-2 omicron subvariants to therapeutic monoclonal antibodies

    1. Daichi Yamasoba
    2. Yusuke Kosugi
    3. Izumi Kimura
    4. Shigeru Fujita
    5. Keiya Uriu
    6. Jumpei Ito
    7. Kei Sato

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  5. Soluble MAC is primarily released from MAC-resistant bacteria that potently convert complement component C5

    1. Dennis J Doorduijn
    2. Marie V Lukassen
    3. Marije FL van 't Wout
    4. Vojtech Franc
    5. Maartje Ruyken
    6. Bart W Bardoel
    7. Albert JR Heck
    8. Suzan HM Rooijakkers

    • Curated by eLife

      Evaluation Summary:

      The soluble membrane attack complex (sMAC) is generated from complement activation and contains the complement proteins C5b, C6, C7, C8, C9 together with the regulatory proteins clusterin and vitronectin. Despite intense interest in sMAC, the mechanisms regulating its formation remain poorly understood. In this manuscript the authors demonstrate that sMAC is formed when complement is activated on bacteria that are resistant to killing by MAC pores.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #2 agreed to share their name with the authors.)

    Reviewed by eLife

    3 evaluationsAppears in 1 listLatest version Latest activity

  6. Gas6 drives Zika virus-induced neurological complications in humans and congenital syndrome in immunocompetent mice

    1. Joao Luiz Silva-Filho
    2. Lilian Gomes de Oliveira
    3. Leticia Monteiro
    4. Pierina L. Parise
    5. Nagela G. Zanluqui
    6. Carolina M. Polonio
    7. Carla Longo de Freitas
    8. Daniel A. Toledo-Teixeira
    9. William M. Souza
    10. Najara Bittencourt
    11. Mariene R. Amorim
    12. Julia Forato
    13. Stéfanie Primon Muraro
    14. Gabriela Fabiano de Souza
    15. Matheus Cavalheiro Martini
    16. Karina Bispos-dos-Santos
    17. Carla C. Judice
    18. Maria Laura Costa
    19. Rodrigo N. Angerami
    20. André R. R. Freitas
    21. Mariangela R. Resende
    22. Márcia T. Garcia
    23. Maria Luiza Moretti
    24. The Zika-Unicamp Network
    25. Laurent Renia
    26. Lisa F. P. Ng
    27. Carla V. Rothlin
    28. Fabio TM Costa
    29. Jean Pierre Schatzmann Peron
    30. José Luiz Proença-Modena

    • Curated by eLife

      Evaluation Summary:

      The pathophysiology of Zika virus infection remains an area of high research interest. In this study, the authors use diverse experimental models to examine the potential role of Gas6 in Zika virus infection and associated neurological sequelae.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. The reviewers remained anonymous to the authors.)

    Reviewed by eLife

    4 evaluationsAppears in 1 listLatest version Latest activity

  7. Nsp1 proteins of human coronaviruses HCoV-OC43 and SARS-CoV2 inhibit stress granule formation

    1. Stacia M. Dolliver
    2. Mariel Kleer
    3. Maxwell P. Bui-Marinos
    4. Shan Ying
    5. Jennifer A. Corcoran
    6. Denys A. Khaperskyy

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  8. The highly conserved stem-loop II motif is important for the lifecycle of astroviruses but dispensable for SARS-CoV-2

    1. Andrew B Janowski
    2. Hongbing Jiang
    3. Chika Fujii
    4. Macee C Owen
    5. Traci L Bricker
    6. Tamarand L Darling
    7. Houda H. Harastani
    8. Kuljeet Seehra
    9. Stephen Tahan
    10. Ana Jung
    11. Binita Febles
    12. Joshua A Blatter
    13. Scott A Handley
    14. Bijal A Parikh
    15. Valeria Lulla
    16. Adrianus CM Boon
    17. David Wang

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  9. A Bacteriophage-Based, Highly Efficacious, Needle- and Adjuvant-Free, Mucosal COVID-19 Vaccine

    1. Jingen Zhu
    2. Swati Jain
    3. Jian Sha
    4. Himanshu Batra
    5. Neeti Ananthaswamy
    6. Paul B. Kilgore
    7. Emily K. Hendrix
    8. Yashoda M. Hosakote
    9. Xiaorong Wu
    10. Juan P. Olano
    11. Adeyemi Kayode
    12. Cristi L. Galindo
    13. Simran Banga
    14. Aleksandra Drelich
    15. Vivian Tat
    16. Chien-Te K. Tseng
    17. Ashok K. Chopra
    18. Venigalla B. Rao

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  10. Removal of clinically relevant SARS-CoV-2 variants by an affinity resin containing Galanthus nivalis agglutinin

    1. Melanie Gooldy
    2. Christelle M. Roux
    3. Steven P. LaRosa
    4. Nicole Spaulding
    5. Charles J. Fisher

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity
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