Microbiology

A Blueprint for Broadly Effective Bacteriophage Therapy Against Bacterial Infections

1. Minyoung Kevin Kim
2. Qingquan Chen
3. Arne Echterhof
4. Robert C. McBride
5. Nina Pennetzdorfer
6. Niaz Banaei
7. Elizabeth B. Burgener
8. Carlos E. Milla
9. Paul L. Bollyky

Reviewed by Rapid Reviews Infectious Diseases, Arcadia Science, PREreview

Modulation of host signalling pathways reveal a major role for Wnt signalling in the maturation of Plasmodium falciparum liver schizonts

1. Abhishek Kanyal
2. Geert-Jan van Gemert
3. Haoyu Wu
4. Alex van der Starre
5. Johannes HW de Wilt
6. Teun Bousema
7. Robert W. Sauerwein
8. Richard Bartfai
9. Annie SP Yang

Reviewed by Rapid Reviews Infectious Diseases

Mosquito immune cells enhance dengue and Zika virus dissemination in Aedes aegypti

1. David R. Hall
2. Rebecca M. Johnson
3. Hyeogsun Kwon
4. Zannatul Ferdous
5. S. Viridiana Laredo-Tiscareño
6. Bradley J. Blitvich
7. Doug E. Brackney
8. Ryan C. Smith

Reviewed by Rapid Reviews Infectious Diseases

Interleukin-27 is antiviral at the maternal-fetal interface

1. Madeline S. Merlino
2. Briah Barksdale
3. Seble G. Negatu
4. Rebecca L. Clements
5. Taylor Miller-Ensminger
6. Alexandra H. Lopez
7. Sneha Mani
8. Monica N. Mainigi
9. Christopher A. Hunter
10. Kellie A. Jurado

Reviewed by Arcadia Science

An infection and pathogenesis mouse model of SARS-CoV-2-related pangolin coronavirus GX_P2V(short_3UTR)

1. Lai Wei
2. Shuiqing Liu
3. Shanshan Lu
4. Shengdong Luo
5. Xiaoping An
6. Huahao Fan
7. Weiwei Chen
8. Erguang Li
9. Yigang Tong
10. Lihua Song

Reviewed by Rapid Reviews Infectious Diseases

Scrutinized lipid utilization disrupts Amphotericin-B responsiveness in clinical isolates of Leishmania donovani

1. Supratim Pradhan
2. Dhruba Dhar
3. Debolina Manna
4. Shubhangi Chakraborty
5. Arkapriya Bhattacharyya
6. Khushi Chauhan
7. Rimi Mukherjee
8. Abhik Sen
9. Krishna Pandey
10. Soumen Das
11. Budhaditya Mukherjee

• Curated by eLife

  eLife Assessment

  This important study investigates the propensity of the intravacuolar pathogen, Leishmania, to scavenge lipids which it utilizes for its accelerated growth within macrophages. The authors present compelling evidence that supports this hypothesis, although the genetic basis for the parasite's requirement for lipids remains unresolved. The study adds to other work that has implicated pathogen-derived processes in the selective recruitment of vesicles to the pathogen-containing vacuole, based on the content of the cargo.

Reviewed by eLife

Single-dose VSV-Sudan virus vaccine protects from lethal Sudan virus infection within one week: a challenge study in macaques

1. Paige Fletcher
2. Kyle L. O’Donnell
3. Friederike Feldmann
4. Joseph F. Rhoderick
5. Chad S. Clancy
6. Cecilia A. Prator
7. Brian J. Smith
8. Bronwyn M. Gunn
9. Heinz Feldmann
10. Andrea Marzi

Reviewed by Rapid Reviews Infectious Diseases

The antifungal and other bioactive properties of the volatilome of Streptomyces scabiei

1. Nudzejma Stulanovic
2. Djulia Bensaada
3. Loïc Belde
4. Delphine Adam
5. Marc Hanikenne
6. Jean-François Focant
7. Pierre-Hugues Stefanuto
8. Sébastien Rigali

Reviewed by Arcadia Science

Secretory leukocyte protease inhibitor influences periarticular joint inflammation in Borrelia burgdorferi-infected mice

1. Qian Yu
2. Xiaotian Tang
3. Thomas Hart
4. Robert Homer
5. Alexia A Belperron
6. Linda K Bockenstedt
7. Aaron Ring
8. Akira Nakamura
9. Erol Fikrig

• Curated by eLife

  eLife Assessment

  This study presents a valuable finding on the role of secretory leukocyte protease inhibitors (SLPI) in developing Lyme disease in mice infected with Borrelia burgdorferi. The evidence supporting the authors' claims is solid. However, several concerns raised by the reviewers remain unaddressed. This paper would be of interest to scientists in the infectious inflammatory disease field.

Reviewed by eLife

Implementation of a multiplex PCR amplfication system combined with next-generation genome sequencing to decipher the circulation of Human coronavirus 229E lineages in Southern France

1. Houmadi HIKMAT
2. Justine PY
3. Celine BOSCHI
4. Emilie BUREL
5. Lorlane LE TARGA
6. Matthieu MILLION
7. Lucile LESAGE
8. Aurelie MORAND
9. Bernard LA SCOLA
10. Philippe COLSON

Reviewed by PREreview