1. Distinct adaptation and epidemiological success of different genotypes within Salmonella enterica serovar Dublin

    This article has 9 authors:
    1. Cheryll M Sia
    2. Rebecca L Ambrose
    3. Mary Valcanis
    4. Patiyan Andersson
    5. Susan A Ballard
    6. Benjamin P Howden
    7. Deborah A Williamson
    8. Jaclyn S Pearson
    9. Danielle J Ingle
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This study provides valuable insights into the evolutionary histories and cellular infection responses of two Salmonella Dublin genotypes. While the evidence is compelling, a more phylogenetically diverse bacterial collection would enhance the findings. This research is relevant to scientists studying Salmonella and gastroenteritis-related pathogens.

    Reviewed by eLife

    This article has 7 evaluationsAppears in 1 listLatest version Latest activity
  2. Characterisation and comparison of semen microbiota and bacterial load in men with infertility, recurrent miscarriage, or proven fertility

    This article has 19 authors:
    1. Shahriar Mowla
    2. Linda Farahani
    3. Tharu Tharakan
    4. Rhianna Davies
    5. Gonçalo DS Correia
    6. Yun S Lee
    7. Samit Kundu
    8. Shirin Khanjani
    9. Emad Sindi
    10. Raj Rai
    11. Lesley Regan
    12. Dalia Khalifa
    13. Ralf Henkel
    14. Suks Minhas
    15. Waljit S Dhillo
    16. Jara Ben Nagi
    17. Phillip R Bennett
    18. David A MacIntyre
    19. Channa N Jayasena
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This valuable study reports a potential connection between the seminal microbiome and sperm quality/male fertility. The data are generally convincing. This study will be of interest to clinicians and biomedical researchers who work on microbiome and male fertility.

    Reviewed by eLife

    This article has 9 evaluationsAppears in 3 listsLatest version Latest activity
  3. Structural basis for collagen recognition by the Streptococcus pyogenes M3 protein and its involvement in biofilm

    This article has 19 authors:
    1. Marta Wojnowska
    2. Takeaki Wajima
    3. Tamas Yelland
    4. Hannes Ludewig
    5. Robert M Hagan
    6. Grant Watt
    7. Samir W Hamaia
    8. Dominique Bihan
    9. Jean-Daniel Malcor
    10. Arkadiusz Bonna
    11. Helena Bergsten
    12. Mattias Svensson
    13. Oddvar Oppegaard
    14. Steinar Skrede
    15. Per Arnell
    16. Ole Hyldegaard
    17. Richard W Farndale
    18. Anna Norrby-Teglund
    19. Ulrich Schwarz-Linek
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      In this paper, the authors report important structural and functional findings on the interaction of how the group A streptococci (GAS) M3 protein (expressed on GAS strains emm3, which are associated with invasive disease) binds to human collagens. They demonstrate an unusual T-shaped structure within the N-terminal hypervariable region of M3 protein that can bind two copies of collagen triple helix in parallel. These solid data advance understanding of how GAS M3 interacts with human collagen, information relevant to understanding and developing treatments for GAS infection. A major limitation of the work is the lack of mutational work to test if the T-shaped structure is necessary for binding collagen.

    Reviewed by eLife

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
  4. Whole Genome Sequencing Reveals Enterobacter hormaechei as a Key Bloodstream Pathogen in Six Tertiary Care Hospitals in Southwestern Nigeria

    This article has 26 authors:
    1. Faith I. Oni
    2. Ayorinde O. Afolayan
    3. Anderson O. Oaikhena
    4. Erkison Ewomazino Odih
    5. Odion O. Ikhimiukor
    6. Veronica O. Ogunleye
    7. Aaron O. Aboderin
    8. Olatunde F. Olabisi
    9. Adewale A. Amupitan
    10. Abayomi Fadeyi
    11. Rasaki A. Raheem
    12. Bashirat A. Olanipekun
    13. Charles J. Elikwu
    14. Oluwadamilola A. Sadare
    15. Phillip O. Oshun
    16. Oyinlola O. Oduyebo
    17. Folashade Ojo
    18. Abolaji T. Adeyemo
    19. Ifeanyi E Mba
    20. Abiodun Egwuenu
    21. Tochi Okwor
    22. Anthony Underwood
    23. Silvia Argimón
    24. Chikwe Ihekweazu
    25. David M. Aanensen
    26. Iruka N. Okeke

    Reviewed by Rapid Reviews Infectious Diseases

    This article has 3 evaluationsAppears in 1 listLatest version Latest activity
  5. Discovery of antibiotics in the archaeome using deep learning

    This article has 3 authors:
    1. Marcelo D. T. Torres
    2. Fangping Wan
    3. Cesar de la Fuente-Nunez

    Reviewed by Arcadia Science

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  6. A functional interleukin-4 homolog is encoded in the genome of infectious laryngotracheitis virus: unveiling a novel virulence factor

    This article has 10 authors:
    1. Jeremy D. Volkening
    2. Stephen J. Spatz
    3. Maricarmen García
    4. Teresa A. Ross
    5. Daniel A. Maekawa
    6. Kenneth S. Rosenthal
    7. Ana C. Zamora
    8. April Skipper
    9. Julia Blakey
    10. Roshan Paudel

    Reviewed by Arcadia Science

    This article has 5 evaluationsAppears in 1 listLatest version Latest activity
  7. Morphology-dependent entry kinetics and spread of influenza A virus

    This article has 15 authors:
    1. Sarah Peterl
    2. Carmen M. Lahr
    3. Carl N. Schneider
    4. Janis Meyer
    5. Xenia Podlipensky
    6. Vera Lechner
    7. Maria Villiou
    8. Larissa Eis
    9. Steffen Klein
    10. Charlotta Funaya
    11. Elisabetta Ada Cavalcanti-Adam
    12. Frederik Graw
    13. Christine Selhuber-Unkel
    14. Karl Rohr
    15. Petr Chlanda

    Reviewed by Review Commons, PREreview

    This article has 5 evaluationsAppears in 2 listsLatest version Latest activity
  8. Effects of parental care on skin microbial community composition in poison frogs

    This article has 9 authors:
    1. Marie-Therese Fischer
    2. Katherine S Xue
    3. Elizabeth K Costello
    4. Mai Dvorak
    5. Gaëlle Raboisson
    6. Anna Robaczewska
    7. Stephanie N Caty
    8. David A Relman
    9. Lauren A O’Connell
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This study provides an important first look at the influence of vertical transmission in the establishment of the amphibian microbiome, with a specific focus on the potential role of parental care. Through a combination of cross-fostering experimental work, comparative analysis across species that show variable levels of care, and developmental time series, the authors provide convincing evidence that vertical transmission through care is possible, but incomplete evidence that it plays a significant role in shaping frog skin microbiomes in nature or across time. This work will be of interest to researchers studying the evolution of parental care and microbiomes in vertebrates.

    Reviewed by eLife

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
  9. Neutralizing human monoclonal antibodies that target the PcrV component of the Type III Secretion System of Pseudomonas aeruginosa act through distinct mechanisms

    This article has 14 authors:
    1. Jean-Mathieu Desveaux
    2. Eric Faudry
    3. Carlos Contreras-Martel
    4. François Cretin
    5. Leonardo Sebastian Dergan-Dylon
    6. Axelle Amen
    7. Isabelle Bally
    8. Victor Tardivy-Casemajor
    9. Fabien Chenavier
    10. Delphine Fouquenet
    11. Yvan Caspar
    12. Ina Attrée
    13. Andréa Dessen
    14. Pascal Poignard
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This useful study identifies new monoclonal antibodies produced by cystic fibrosis patients against the Pseudomonas aeruginosa type three secretion system. The evidence supporting the authors' claim is solid. However, in the current version of the manuscript, it is unclear what the benefits of the newly isolated antibodies are with respect to antibodies previously identified using a similar approach. The study will be of interest to those working on developing mAbs against Pseudomonas aeruginosa and also against other pathogens that harbor the T3SS.

    Reviewed by eLife

    This article has 3 evaluationsAppears in 1 listLatest version Latest activity
  10. Alveolar metabolite availability facilitates secondary infection by Pseudomonas aeruginosa in acutely injured lungs

    This article has 18 authors:
    1. Jennifer M. Baker
    2. Thomas L. Flott
    3. Laura A. McLellan
    4. Ingrid G. Bustos
    5. Jose L. Guerrero
    6. Lina M. Mendez
    7. Annastasia M. Petouhoff
    8. Piyush Ranjan
    9. Joseph D. Metcalf
    10. Roderick A. McDonald
    11. Nicole R. Falkowski
    12. Ying He
    13. Mónica P. Cala
    14. Gary B. Huffnagle
    15. Michael W. Sjoding
    16. Luis F. Reyes
    17. Kathleen A. Stringer
    18. Robert P. Dickson

    Reviewed by PREreview

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
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