Infectious Diseases (except HIV/AIDS)

Stem-like CD8+ T cells preserve HBV-specific responses in HBV/HIV co-infection

1. Jay Preechanukul
2. Aljawharah Alrubayyi
3. Bo Sun
4. Edward Arbe-Barnes
5. Jonida Kokici
6. Frances Gorou
7. Sarun Prasitdumrong
8. Kelly A.S. da Costa
9. Natasha Fisher-Pearson
10. Noshin Hussain
11. Stephanie Kucykowicz
12. Indrajit Ghosh
13. Fiona Burns
14. Sabine Kinloch
15. Pedro Simoes
16. Sanjay Bhagani
17. Patrick T F Kennedy
18. Mala K Maini
19. Rachael Bashford-Rogers
20. Upkar S Gill
21. Dimitra Peppa

Reviewed by Rapid Reviews Infectious Diseases, PREreview

Age-specific immunity to rotavirus infection and the risk of disease before and after rotavirus vaccine introduction in the United Kingdom: an observational, seroepidemiological study

1. Daniel Hungerford
2. Virgina E. Pitzer
3. Khuzwayo C. Jere
4. Marc Y R Henrion
5. Jonathan Mandolo
6. Catherine Beavis
7. Karen Ryan
8. Jenna Lowe
9. Nigel A. Cunliffe
10. Neil French
11. Miren Iturriza-Gómara

Reviewed by Rapid Reviews Infectious Diseases

A multiplex Mtb-specific FluoroSpot assay measuring IFNγ, TNF, and IL2-secreting cells can improve accuracy and differentiation across the tuberculosis spectrum

1. Elin Folkesson
2. Fariba Foroogh
3. Vera Kjellgren
4. Mathilda Jakobsson
5. Lisann Grunewald
6. Jens Hellberg
7. Carolina Sousa Silva
8. Maia S. Gower
9. Linn Kleberg
10. Hans Grönlund
11. Margarida Correia-Neves
12. Bartek Makower
13. Gunilla Källenius
14. Judith Bruchfeld
15. Christopher Sundling

Reviewed by Rapid Reviews Infectious Diseases

The impact of different antimicrobial exposures on the gut microbiome in the ARMORD observational study

1. Leon Peto
2. Nicola Fawcett
3. Musaiwale M Kamfose
4. Claire Scarborough
5. Andy Peniket
6. Robert Danby
7. Tim EA Peto
8. Derrick W Crook
9. Martin J Llewelyn
10. A Sarah Walker

• Curated by eLife

  eLife Assessment

  This study offers a valuable assessment of the impact of antibiotics on the human gut microbiota across diverse observational cohorts. The findings presented are convincing, despite the observational design and residual confounding that may still contribute to discrepancies between the cross-sectional and longitudinal data. The work is relevant for researchers and clinicians interested in antimicrobial resistance and the impact of antibiotics on the host.

Reviewed by eLife

Single-cell immune profiling at time of M. tuberculosis exposure reveals antigen-reactive programs that predict progression to active disease

1. Jonathan Penã Avila
2. Joshua Simmons
3. Marina C. Figueiredo
4. Megan Turner
5. Marcelo Cordeiro-Santos
6. Valeria C. Rolla
7. Afranio L. Kristki
8. Rama Gangula
9. Cynthia Nochowicz
10. Ramesh Ram
11. Samuel Bailin
12. Simon Mallal
13. Silvana Gaudieri
14. Eric Alves
15. Beatriz Barreto Barreto-Duarte
16. Artur T. L. Queiroz
17. Helder I. Nakaya
18. Bruno B. Andrade
19. Timothy R. Sterling
20. Spyros A. Kalams
21. RePORT-Brazil Consortium

Reviewed by Rapid Reviews Infectious Diseases

An age-stratified mathematical model to inform optimal measles vaccination strategies

1. Samiran Ghosh
2. Indrajit Ghosh
3. Siuli Mukhopadhyay

Reviewed by Rapid Reviews Infectious Diseases

Uptake and feasibility of task-shifting of Xpert MTB/RIF Ultra testing from laboratory technicians to nurses to increase access and reduce time to results: a multi-country mixed method research

1. Eden Masama Ngu
2. Basant Joshi
3. Bandana Bhatta
4. Minh Huyen Ton Nu Nguyet
5. Manon Lounnas
6. Rodney Kaitano
7. Marcelle N’Guessan
8. Kunda Kasakwa
9. Emelva Manhiça
10. Song Yin
11. Jacob Mugisha
12. Timothée Ouassa
13. Jean-Voisin Taguebue
14. Raoul Moh
15. Guillaume Breton
16. Juliet Mwanga-Amumpere
17. Laurence Borand
18. Chishala Chabala
19. Celso Khosa
20. Eric Wobudeya
21. Olivier Marcy
22. Joanna Orne-Gliemann
23. Maryline Bonnet

Reviewed by Rapid Reviews Infectious Diseases, PREreview

Evaluation of person-centred outcome measures for use in clinical trials of tuberculosis therapeutics

1. Conor D Tweed
2. Annabelle South
3. Suzanne Staples
4. Bazarragchaa Tsogt
5. Nestani Tukvadze
6. Rebecca M Turner
7. Stephan Dressler
8. Adam T Gray
9. Blessina Kumar
10. Oxana Rucsineanu
11. Paul Sommerfeld
12. Rochelle Burgess
13. Hanif Esmail

Reviewed by Rapid Reviews Infectious Diseases

Projected ecological and disruptive impacts of climate change on malaria in Africa

1. Tasmin L. Symons
2. Alexander Moran
3. Ann Balzarolo
4. Camilo Vargas
5. Mairi Robertson
6. Jailos Lubinda
7. Adam Saddler
8. Michael McPhail
9. Joseph Harris
10. Jennifer Rozier
11. Annie Browne
12. Punam Amratia
13. Amelia Bertozzi-Villa
14. Samir Bhatt
15. Ewan Cameron
16. Nick Golding
17. David L. Smith
18. Abdisalan M. Noor
19. Susan F. Rumisha
20. Matthew D. Palmer
21. Daniel J. Weiss
22. Naomi Desai
23. David Potere
24. Nicholas Sukitsch
25. Wendy Woods
26. Peter W. Gething

Reviewed by Rapid Reviews Infectious Diseases

Type I interferon responses contribute to immune protection against mycobacterial infection

1. Andrea Szydlo-Shein
2. Blanca Sanz-Magallón Duque de Estrada
3. Joshua Rosenheim
4. Carolin T Turner
5. Aneesh Chandran
6. Evdokia Tsaliki
7. Marc CI Lipman
8. Heinke Kunst
9. Gabriele Pollara
10. Philip M Elks
11. Jean-Pierre Levraud
12. Elspeth M Payne
13. Mahdad Noursadeghi
14. Gillian S Tomlinson

• Curated by eLife

  eLife Assessment

  This useful study shows a protective role of type 1 IFN during Mycobacterium tuberculosis infection. It shows that the type 1 IFN response in human skin TST inversely correlates with TB severity, suggesting its protective role. Considering that type I IFN is usually shown to be pro-pathogenic, the higher vulnerability of zebrafish larvae lacking stat2 to M marinum infection is a strong result. However, the conclusion that IFN-I is protective during mycobacterial infection remains indirect and incomplete; the study requires additional mechanistic insights and validation.

Reviewed by eLife