Immunology

  1. Targeting the chemokine receptor CXCR4 with histamine analogue to reduce inflammation in juvenile arthritis: a proof of concept for COVID-19 therapeutic approach

    1. Nassima Bekaddour
    2. Nikaïa Smith
    3. Benoit Beitz
    4. Alba Llibre
    5. Tom Dott
    6. Anne Baudry
    7. Anne-Sophie Korganow
    8. Sébastien Nisole
    9. Richard Mouy
    10. Sylvain Breton
    11. Brigitte Bader-Meunier
    12. Darragh Duffy
    13. Benjamin Terrier
    14. Benoit Schneider
    15. Pierre Quartier
    16. Mathieu P Rodero
    17. Jean-Philippe Herbeuval

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  2. Mutagenic Distinction between the Receptor-Binding and Fusion Subunits of the SARS-CoV-2 Spike Glycoprotein and Its Upshot

    1. Robert Clark Penner

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  3. Dromedary camel nanobodies broadly neutralize SARS-CoV-2 variants

    1. Jessica Hong
    2. Hyung Joon Kwon
    3. Raul Cachau
    4. Catherine Z. Chen
    5. Kevin John Butay
    6. Zhijian Duan
    7. Dan Li
    8. Hua Ren
    9. Tianyuzhou Liang
    10. Jianghai Zhu
    11. Venkata P. Dandey
    12. Negin P. Martin
    13. Dominic Esposito
    14. Uriel Ortega-Rodriguez
    15. Miao Xu
    16. Mario J. Borgnia
    17. Hang Xie
    18. Mitchell Ho

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  4. A self-amplifying mRNA COVID-19 vaccine drives potent and broad immune responses at low doses that protects non-human primates against SARS-CoV-2

    1. Amy R. Rappaport
    2. Sue-Jean Hong
    3. Ciaran D. Scallan
    4. Leonid Gitlin
    5. Arvin Akoopie
    6. Gregory R. Boucher
    7. Milana Egorova
    8. J. Aaron Espinosa
    9. Mario Fidanza
    10. Melissa A. Kachura
    11. Annie Shen
    12. Gloria Sivko
    13. Anne Van Abbema
    14. Robert L. Veres
    15. Karin Jooss

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  5. Prime-boost vaccination regimens with INO-4800 and INO-4802 augment and broaden immune responses against SARS-CoV-2 in nonhuman primates

    1. Jewell N. Walters
    2. Blake Schouest
    3. Ami Patel
    4. Emma L. Reuschel
    5. Katherine Schultheis
    6. Elizabeth Parzych
    7. Igor Maricic
    8. Ebony N. Gary
    9. Mansi Purwar
    10. Viviane M. Andrade
    11. Arthur Doan
    12. Dustin Elwood
    13. Zeena Eblimit
    14. Brian Nguyen
    15. Drew Frase
    16. Faraz I. Zaidi
    17. Abhijeet Kulkarni
    18. Alison Generotti
    19. J Joseph Kim
    20. Laurent M. Humeau
    21. Stephanie J. Ramos
    22. Trevor R.F. Smith
    23. David B. Weiner
    24. Kate E. Broderick

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  6. Statistics of antibody binding to the spike protein explain the dependence of COVID 19 infection risk on antibody concentration and affinity

    1. David E. Williams

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  7. Phage-like particle vaccines are highly immunogenic and protect against pathogenic coronavirus infection and disease

    1. Bennett J. Davenport
    2. Alexis Catala
    3. Stuart M. Weston
    4. Robert M. Johnson
    5. Jeremy Ardanuy
    6. Holly L. Hammond
    7. Carly Dillen
    8. Matthew B. Frieman
    9. Carlos E. Catalano
    10. Thomas E. Morrison

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  8. SARS-CoV-2 Envelope protein (E) binds and activates TLR2: A novel target for COVID-19 interventions

    1. Rémi Planès
    2. Jean-Baptiste Bert
    3. Sofiane Tairi
    4. Lbachir Benmohamed
    5. Elmostafa Bahraoui

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  9. Scrutiny of human lung infection by SARS-CoV-2 and associated human immune responses in humanized mice

    1. Renren Sun
    2. Zongzheng Zhao
    3. Cong Fu
    4. Yixin Wang
    5. Zhendong Guo
    6. Chunmao Zhang
    7. Lina Liu
    8. Cheng Zhang
    9. Chang Shu
    10. Jin He
    11. Shucheng Hua
    12. Yuwei Gao
    13. Zheng Hu

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  10. Modelling the response to vaccine in non-human primates to define SARS-CoV-2 mechanistic correlates of protection

    1. Marie Alexandre
    2. Romain Marlin
    3. Mélanie Prague
    4. Severin Coleon
    5. Nidhal Kahlaoui
    6. Sylvain Cardinaud
    7. Thibaut Naninck
    8. Benoit Delache
    9. Mathieu Surenaud
    10. Mathilde Galhaut
    11. Nathalie Dereuddre-Bosquet
    12. Mariangela Cavarelli
    13. Pauline Maisonnasse
    14. Mireille Centlivre
    15. Christine Lacabaratz
    16. Aurelie Wiedemann
    17. Sandra Zurawski
    18. Gerard Zurawski
    19. Olivier Schwartz
    20. Rogier W Sanders
    21. Roger Le Grand
    22. Yves Levy
    23. Rodolphe Thiébaut

    • Curated by eLife

      Evaluation Summary:

      This work should be of interest to a broad readership in infectious diseases, especially those people interested in modeling of infections. It combines statistical and mechanistic modeling to find assayable correlates of immunity for vaccines. This method could be relevant to many diseases or vaccines, although the particular markers identified here likely will be limited in their generalizability.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. The reviewers remained anonymous to the authors.)

    Reviewed by eLife, ScreenIT

    6 evaluationsAppears in 2 listsLatest version Latest activity
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