Immunology

  1. T Cell Response following Anti-COVID-19 BNT162b2 Vaccination Is Maintained against the SARS-CoV-2 Omicron B.1.1.529 Variant of Concern

    1. Hila Cohen
    2. Shahar Rotem
    3. Uri Elia
    4. Gal Bilinsky
    5. Itzchak Levy
    6. Theodor Chitlaru
    7. Erez Bar-Haim

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  2. A potent alpaca-derived nanobody that neutralizes SARS-CoV-2 variants

    1. Jules B. Weinstein
    2. Timothy A. Bates
    3. Hans C. Leier
    4. Savannah K. McBride
    5. Eric Barklis
    6. Fikadu G. Tafesse

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  3. Molecular basis of broad neutralization against SARS-CoV-2 variants including Omicron by a human antibody

    1. Bin Ju
    2. Qingbing Zheng
    3. Huimin Guo
    4. Qing Fan
    5. Tingting Li
    6. Shuo Song
    7. Hui Sun
    8. Senlin Shen
    9. Xinrong Zhou
    10. Lin Cheng
    11. Wenhui Xue
    12. Lingyan Cui
    13. Bing Zhou
    14. Xiangyang Ge
    15. Haiyan Wang
    16. Miao Wang
    17. Shaowei Li
    18. Ningshao Xia
    19. Zheng Zhang

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  4. SARS-CoV-2 Delta variant induces enhanced pathology and inflammatory responses in K18-hACE2 mice

    1. Katherine S. Lee
    2. Ting Y. Wong
    3. Brynnan P. Russ
    4. Alexander M. Horspool
    5. Olivia A. Miller
    6. Nathaniel A. Rader
    7. Jerome P. Givi
    8. Michael T. Winters
    9. Zeriel Y. A. Wong
    10. Holly A. Cyphert
    11. James Denvir
    12. Peter Stoilov
    13. Mariette Barbier
    14. Nadia R. Roan
    15. Md. Shahrier Amin
    16. Ivan Martinez
    17. Justin R. Bevere
    18. F. Heath Damron

    Reviewed by ScreenIT

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  5. Progressive enhancement of kinetic proofreading in T cell antigen discrimination from receptor activation to DAG generation

    1. Derek M Britain
    2. Jason P Town
    3. Orion David Weiner

    • Curated by eLife

      Evaluation Summary:

      In this manuscript, a light-gated receptor system (LOV2) linked to T cell receptor signaling machinery is enhanced by addition of an adhesion system enabling robust operation over a larger range of kinetic parameters. This system enables an exploration of how kinetic proofreading processes executed in seconds relate to T cell activation program involving reactions taking minutes to hours.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. The reviewers remained anonymous to the authors.)

    Reviewed by eLife

    4 evaluationsAppears in 1 listLatest version Latest activity

  6. Obesity associated with attenuated tissue immune cell responses in COVID-19

    1. Shuang A. Guo
    2. Georgina S. Bowyer
    3. John R. Ferdinand
    4. Mailis Maes
    5. Zewen K. Tuong
    6. Eleanor Gilman
    7. Mingfeng Liao
    8. Rik G. H. Lindeboom
    9. Masahiro Yoshida
    10. Kaylee Worlock
    11. Huda Gopee
    12. Emily Stephenson
    13. Paul A. Lyons
    14. Kenneth G.C. Smith
    15. Muzlifah Haniffa
    16. Kerstin B. Meyer
    17. Marko Z. Nikolić
    18. Zheng Zhang
    19. Richard G. Wunderink
    20. Alexander V. Misharin
    21. Gordon Dougan
    22. Vilas Navapurkar
    23. Sarah A. Teichmann
    24. Andrew Conway-Morris
    25. Menna R. Clatworthy

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  7. Tuftsin: A Natural Molecule Against SARS-CoV-2 Infection

    1. Jiahao Huang
    2. Jing Wang
    3. Yan Li
    4. Ziyuan Wang
    5. Ming Chu
    6. Yuedan Wang

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  8. Immunogenicity of convalescent and vaccinated sera against clinical isolates of ancestral SARS-CoV-2, Beta, Delta, and Omicron variants

    1. Arinjay Banerjee
    2. Jocelyne Lew
    3. Andrea Kroeker
    4. Kaushal Baid
    5. Patryk Aftanas
    6. Kuganya Nirmalarajah
    7. Finlay Maguire
    8. Robert Kozak
    9. Ryan McDonald
    10. Amanda Lang
    11. Volker Gerdts
    12. Sharon E. Straus
    13. Lois Gilbert
    14. Angel Xinliu Li
    15. Mohammad Mozafarihashjin
    16. Sharon Walmsley
    17. Anne-Claude Gingras
    18. Jeffrey L. Wrana
    19. Tony Mazzulli
    20. Karen Colwill
    21. Allison J. McGeer
    22. Samira Mubareka
    23. Darryl Falzarano

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  9. An antibody targeting the N-terminal domain of SARS-CoV-2 disrupts the spike trimer

    1. Naveenchandra Suryadevara
    2. Andrea R. Shiakolas
    3. Laura A. VanBlargan
    4. Elad Binshtein
    5. Rita E. Chen
    6. James Brett Case
    7. Kevin J. Kramer
    8. Erica C. Armstrong
    9. Luke Myers
    10. Andrew Trivette
    11. Christopher Gainza
    12. Rachel S. Nargi
    13. Christopher N. Selverian
    14. Edgar Davidson
    15. Benjamin J. Doranz
    16. Summer M. Diaz
    17. Laura S. Handal
    18. Robert H. Carnahan
    19. Michael S. Diamond
    20. Ivelin S. Georgiev
    21. James E. Crowe

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  10. COVID-19 vaccine booster induces a strong CD8 + T cell response against Omicron variant epitopes in HLA-A*02:01 + individuals

    1. Andrea T. Nguyen
    2. Christopher Szeto
    3. Demetra S.M. Chatzileontiadou
    4. Zhen Wei Marcus Tong
    5. Michael J. Dewar-Oldis
    6. Lucy Cooper
    7. Lawton D. Murdolo
    8. Keng Yih Chew
    9. Katie E. Lineburg
    10. Alan Riboldi-Tunicliffe
    11. Rachel Williamson
    12. Bradley J. Gardiner
    13. Dhilshan Jayasinghe
    14. Christian A. Lobos
    15. You Min Ahn
    16. Emma J. Grant
    17. Corey Smith
    18. James McMahon
    19. Kim L. Good-Jacobson
    20. Peter J. Barnard
    21. Kirsty R. Short
    22. Stephanie Gras

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity
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