Immunology

  1. Diet induced obesity and type 2 diabetes drives exacerbated sex-associated disease profiles in K18-hACE2-mice challenged with SARS-CoV-2

    1. Katherine S. Lee
    2. Brynnan P. Russ
    3. Ting Y. Wong
    4. Alexander M. Horspool
    5. Michael T. Winters
    6. Mariette Barbier
    7. Justin R. Bevere
    8. Ivan Martinez
    9. F. Heath Damron
    10. Holly A. Cyphert

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  2. GM-CSF-activated human dendritic cells promote type1 T follicular helper cells (Tfh1) polarization in a CD40-dependent manner

    1. Sarantis Korniotis
    2. Melissa Saichi
    3. Coline Trichot
    4. Caroline Hoffmann
    5. Elise Amblard
    6. Annick Viguier
    7. Sophie Grondin
    8. Floriane Noel
    9. Hamid Mattoo
    10. Vassili Soumelis

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  3. Two types of human TCR differentially regulate reactivity to self and non-self antigens

    1. Assya Trofimov
    2. Philippe Brouillard
    3. Jean-David Larouche
    4. Jonathan Séguin
    5. Jean-Philippe Laverdure
    6. Ann Brasey
    7. Gregory Ehx
    8. Denis-Claude Roy
    9. Lambert Busque
    10. Silvy Lachance
    11. Sébastien Lemieux
    12. Claude Perreault

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  4. Induction of neutralizing antibodies against SARS-CoV-2 variants by a multivalent mRNA-lipid nanoparticle vaccine encoding SARS-CoV-2/SARS-CoV Spike protein receptor-binding domains in mice

    1. Qiong Zhang
    2. Shashi Tiwari
    3. Jing Wen
    4. Shaobo Wang
    5. Lingling Wang
    6. Wanyu Li
    7. Lingzhi Zhang
    8. Stephen Rawling
    9. Yong Cheng
    10. Jesse Jokerst
    11. Tariq M. Rana

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  5. Anti-SARS-Cov-2 S-RBD IgG Formed after BNT162b2 Vaccination Can Bind C1q and Activate Complement

    1. Anas H. A. Abu-Humaidan
    2. Fatima M. Ahmad
    3. Dima Awajan
    4. Raba’a F. Jarrar
    5. Nader Alaridah

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  6. A cocktail containing two synergetic antibodies broadly neutralizes SARS-CoV-2 and its variants including Omicron BA.1 and BA.2

    1. Xinghai Zhang
    2. Feiyang Luo
    3. huajun Zhang
    4. Hangtian Guo
    5. Junhui Zhou
    6. Tingting Li
    7. Shaohong Chen
    8. Shuyi Song
    9. Meiying Shen
    10. Yan Wu
    11. Yan Gao
    12. Xiaojian Han
    13. Yingming Wang
    14. Chao Hu
    15. Yuchi Lu
    16. Wei Wang
    17. Kai Wang
    18. Ni Tang
    19. Tengchuan Jin
    20. Chengyong Yang
    21. Guofeng Cheng
    22. Haitao Yang
    23. Aishun Jin
    24. Xiaoyun Ji
    25. Rui Gong
    26. Sandra Chiu
    27. Ailong Huang

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  7. Macrophages regulate gastrointestinal motility through complement component 1q

    1. Mihir Pendse
    2. Haley De Selle
    3. Nguyen Vo
    4. Gabriella Quinn
    5. Chaitanya Dende
    6. Yun Li
    7. Cristine N Salinas
    8. Tarun Srinivasan
    9. Daniel C Propheter
    10. Alexander A Crofts
    11. Eugene Koo
    12. Brian Hassell
    13. Kelly A Ruhn
    14. Prithvi Raj
    15. Yuuki Obata
    16. Lora V Hooper

    • Curated by eLife

      Evaluation Summary:

      This study will be of broad interest to neuroscientists, immunologists, and gastroenterologists, revealing a novel role of complement C1q in intestinal macrophages and the regulation of gut motility. The manuscript is well written and key datasets are convincing, but the lack of mechanistic details that lead to dysmotility require additional supportive datasets at this time.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #3 agreed to share their name with the authors.)

    Reviewed by eLife

    5 evaluationsAppears in 1 listLatest version Latest activity

  8. Cryo-electron tomography of Birbeck granules reveals the molecular mechanism of langerin lattice formation

    1. Toshiyuki Oda
    2. Haruaki Yanagisawa
    3. Hideyuki Shinmori
    4. Youichi Ogawa
    5. Tatsuyoshi Kawamura

    Reviewed by Review Commons

    3 evaluationsAppears in 1 listLatest version Latest activity

  9. An efficient approach for SARS-CoV-2 monoclonal antibody production via modified mRNA-LNP immunization

    1. Fu-Fei Hsu
    2. Kang-Hao Liang
    3. Monika Kumari
    4. Wan-Yu Chen
    5. Hsiu-Ting Lin
    6. Chao-Min Cheng
    7. Mi-Hua Tao
    8. Han-Chung Wu

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  10. Impaired immune response drives age-dependent severity of COVID-19

    1. Julius Beer
    2. Stefania Crotta
    3. Angele Breithaupt
    4. Annette Ohnemus
    5. Jan Becker
    6. Benedikt Sachs
    7. Lisa Kern
    8. Miriam Llorian
    9. Nadine Ebert
    10. Fabien Labroussaa
    11. Tran Thi Nhu Thao
    12. Bettina Salome Trueeb
    13. Joerg Jores
    14. Volker Thiel
    15. Martin Beer
    16. Jonas Fuchs
    17. Georg Kochs
    18. Andreas Wack
    19. Martin Schwemmle
    20. Daniel Schnepf

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity
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