Immunology

Resistance of SARS-CoV-2 Omicron BA.1 and BA.2 Variants to Vaccine-Elicited Sera and Therapeutic Monoclonal Antibodies

1. Hao Zhou
2. Belinda M. Dcosta
3. Nathaniel R. Landau
4. Takuya Tada

Reviewed by ScreenIT

Mathematical model of a cytokine storm

1. Irina Kareva
2. Faina Berezovskaya
3. Georgy Karev

Reviewed by ScreenIT

Non-productive exposure of PBMCs to SARS-CoV-2 induces cell-intrinsic innate immunity responses

1. Julia Kazmierski
2. Kirstin Friedmann
3. Dylan Postmus
4. Cornelius Fischer
5. Jenny Jansen
6. Anja Richter
7. Laure Bosquillon de Jarcy
8. Christiane Schüler
9. Madlen Sohn
10. Sascha Sauer
11. Christian Drosten
12. Antoine-Emmanuel Saliba
13. Leif Erik Sander
14. Daniela Niemeyer
15. Christine Goffinet

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Reduced antigenicity of Omicron lowers host serologic response

1. Jérôme Tubiana
2. Yufei Xiang
3. Li Fan
4. Haim J. Wolfson
5. Kong Chen
6. Dina Schneidman-Duhovny
7. Yi Shi

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Increased Potency and Breadth of SARS-CoV-2 Neutralizing Antibodies After a Third mRNA Vaccine Dose

1. Frauke Muecksch
2. Zijun Wang
3. Alice Cho
4. Christian Gaebler
5. Tarek Ben Tanfous
6. Justin DaSilva
7. Eva Bednarski
8. Victor Ramos
9. Shuai Zong
10. Brianna Johnson
11. Raphael Raspe
12. Dennis Schaefer-Babajew
13. Irina Shimeliovich
14. Mridushi Daga
15. Kai-Hui Yao
16. Fabian Schmidt
17. Katrina G. Millard
18. Martina Turroja
19. Mila Jankovic
20. Thiago Y. Oliveria
21. Anna Gazumyan
22. Marina Caskey
23. Theodora Hatziioannou
24. Paul D. Bieniasz
25. Michel C. Nussenzweig

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The BNT162b2 mRNA SARS-CoV-2 vaccine induces transient afucosylated IgG1 in naive but not in antigen-experienced vaccinees

1. Julie Van Coillie
2. Tamas Pongracz
3. Johann Rahmöller
4. Hung-Jen Chen
5. Chiara Elisabeth Geyer
6. Lonneke A. van Vught
7. Jana Sophia Buhre
8. Tonći Šuštić
9. Thijs Luc Junior van Osch
10. Maurice Steenhuis
11. Willianne Hoepel
12. Wenjun Wang
13. Anne Sophie Lixenfeld
14. Jan Nouta
15. Sofie Keijzer
16. Federica Linty
17. Remco Visser
18. Mads Delbo Larsen
19. Emily Lara Martin
20. Inga Künsting
21. Selina Lehrian
22. Vera von Kopylow
23. Carsten Kern
24. Hanna Bele Lunding
25. Menno de Winther
26. Niels van Mourik
27. Theo Rispens
28. Tobias Graf
29. Marleen Adriana Slim
30. René Peter Minnaar
31. Marije Kristianne Bomers
32. Jonne Jochum Sikkens
33. Alexander P.J. Vlaar
34. C. Ellen van der Schoot
35. Jeroen den Dunnen
36. Manfred Wuhrer
37. Marc Ehlers
38. Gestur Vidarsson
39. Spinello Antinori
40. Cinzia Bassoli
41. Giovanna Bestetti
42. Mario Corbellino
43. Alice Covizzi
44. Angelica Lupo
45. Laura Milazzo
46. Marco Schiuma
47. Alessandro Torre
48. Brent Appelman
49. Diederik van de Beek
50. Marije K. Bomers
51. Justin de Brabander
52. Matthijs C. Brouwer
53. David T.P. Buis
54. Nora Chekrouni
55. Marit J. van Gils
56. Menno D. de Jong
57. Ayesha H.A. Lavell
58. Niels van Mourik
59. Sabine E. Olie
60. Edgar J.G. Peters
61. Tom D.Y. Reijnders
62. Michiel Schinkel
63. Alex R. Schuurman
64. Jonne J. Sikkens
65. Marleen A. Slim
66. Yvo M. Smulders
67. Alexander P.J. Vlaar
68. Lonneke A. van Vught
69. Joost W. Wiersinga

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Omicron-specific and bivalent omicron-containing vaccine candidates elicit potent virus neutralisation in the animal model

1. Asghar Abdoli
2. Hamidreza Jamshidi
3. Mohammad Taqavian
4. Mehdi Lari Baghal
5. Hasan Jalili

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Redox regulation of PTPN22 affects the severity of T-cell-dependent autoimmune inflammation

1. Jaime James
2. Yifei Chen
3. Clara M Hernandez
4. Florian Forster
5. Markus Dagnell
6. Qing Cheng
7. Amir A Saei
8. Hassan Gharibi
9. Gonzalo Fernandez Lahore
10. Annika Åstrand
11. Rajneesh Malhotra
12. Bernard Malissen
13. Roman A Zubarev
14. Elias SJ Arnér
15. Rikard Holmdahl

• Curated by eLife

  Evaluation summary:

  This paper documents a novel aspect of how T cell activation is regulated by the PTPN22 phosphatase, namely reversible oxidation which transiently reduces the activity of PTPN22 to allow the T cell antigen receptor to drive a strong activation signal. This compelling work adds to our understanding of how an immune response is initiated and provides new insights that could be exploited for the development of new drugs to treat immune-mediated diseases.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #2 agreed to share their name with the authors.)

Reviewed by eLife

Milk of Cow and Goat, Immunized by Recombinant Protein Vaccine ZF-UZ-VAC2001(Zifivax), Contains Neutralizing Antibodies Against SARS-CoV-2 and Remains Active After Standard Milk Pasteurization

1. Victoria Garib
2. Stefani Katsamaki
3. Shahlo Turdikulova
4. Yuliya Levitskaya
5. Nodira Zahidova
6. Galina Bus
7. Kristina Karamova
8. Manona Rakhmedova
9. Nigora Magbulova
10. Alexander Bruhov
11. Firuz Y. Garib
12. Ibrokhim Y. Abdurakhmonov

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Omicron-specific mRNA vaccination alone and as a heterologous booster against SARS-CoV-2

1. Zhenhao Fang
2. Lei Peng
3. Renata Filler
4. Kazushi Suzuki
5. Andrew McNamara
6. Qianqian Lin
7. Paul A. Renauer
8. Luojia Yang
9. Bridget Menasche
10. Angie Sanchez
11. Ping Ren
12. Qiancheng Xiong
13. Madison Strine
14. Paul Clark
15. Chenxiang Lin
16. Albert I. Ko
17. Nathan D. Grubaugh
18. Craig B. Wilen
19. Sidi Chen

Reviewed by ScreenIT