Immunology

Three-dose vaccination-induced immune responses protect against SARS-CoV-2 Omicron BA.2

1. Runhong Zhou
2. Na Liu
3. Xin Li
4. Qiaoli Peng
5. Cheuk-Kwan Yiu
6. Haode Huang
7. Dawei Yang
8. Zhenglong Du
9. Hau-Yee Kwok
10. Ka-Kit Au
11. Jian-Piao Cai
12. Ivan Fan-Ngai Hung
13. Kelvin Kai-Wang To
14. Xiaoning Xu
15. Kwok-Yung Yuen
16. Zhiwei Chen

Reviewed by Rapid Reviews Infectious Diseases, ScreenIT

COVID-19 mRNA third dose induces a unique hybrid immunity-like antibody response

1. Emanuele Andreano
2. Ida Paciello
3. Giulio Pierleoni
4. Giulia Piccini
5. Valentina Abbiento
6. Giada Antonelli
7. Piero Pileri
8. Noemi Manganaro
9. Elisa Pantano
10. Giuseppe Maccari
11. Silvia Marchese
12. Lorena Donnici
13. Linda Benincasa
14. Ginevra Giglioli
15. Margherita Leonardi
16. Concetta De Santi
17. Massimiliano Fabbiani
18. Ilaria Rancan
19. Mario Tumbarello
20. Francesca Montagnani
21. Claudia Sala
22. Duccio Medini
23. Raffaele De Francesco
24. Emanuele Montomoli
25. Rino Rappuoli

Reviewed by ScreenIT

Preclinical evaluation of RQ3013, a broad-spectrum mRNA vaccine against SARS-CoV-2 variants

1. Shudan Tan
2. Jinghua Zhao
3. Xue Hu
4. Yufeng Li
5. Zihan Wu
6. Guoliang Lu
7. Zhaoli Yu
8. Binhe Du
9. Yan Liu
10. Li Li
11. Yuchen Chen
12. Ye Li
13. Yanfeng Yao
14. Xiaoyu Zhang
15. Juhong Rao
16. Ge Gao
17. Yun Peng
18. Hang Liu
19. Zhiming Yuan
20. Jia Liu
21. Qianran Wang
22. Hengrui Hu
23. Xiaobo Gao
24. Hui Zhou
25. Hang Yu
26. Yingjie Xu
27. Wei Yu
28. Lin Feng
29. Manli Wang
30. Chao Shan
31. Jing Lu
32. Jinzhong Lin

Reviewed by ScreenIT

Adenovirus-vectored SARS-CoV-2 vaccine expressing S1-N fusion protein

1. Muhammad S Khan
2. Eun Kim
3. Alex McPherson
4. Florian J Weisel
5. Shaohua Huang
6. Thomas W Kenniston
7. Elena Percivalle
8. Irene Cassaniti
9. Fausto Baldanti
10. Marlies Meisel
11. Andrea Gambotto

Reviewed by ScreenIT

Imprinted antibody responses against SARS-CoV-2 Omicron sublineages

1. Young-Jun Park
2. Dora Pinto
3. Alexandra C. Walls
4. Zhuoming Liu
5. Anna De Marco
6. Fabio Benigni
7. Fabrizia Zatta
8. Chiara Silacci-Fregni
9. Jessica Bassi
10. Kaitlin R. Sprouse
11. Amin Addetia
12. John E. Bowen
13. Cameron Stewart
14. Martina Giurdanella
15. Christian Saliba
16. Barbara Guarino
17. Michael A. Schmid
18. Nicholas M. Franko
19. Jennifer K. Logue
20. Ha V. Dang
21. Kevin Hauser
22. Julia di Iulio
23. William Rivera
24. Gretja Schnell
25. Anushka Rajesh
26. Jiayi Zhou
27. Nisar Farhat
28. Hannah Kaiser
29. Martin Montiel-Ruiz
30. Julia Noack
31. Florian A. Lempp
32. Javier Janer
33. Rana Abdelnabi
34. Piet Maes
35. Paolo Ferrari
36. Alessandro Ceschi
37. Olivier Giannini
38. Guilherme Dias de Melo
39. Lauriane Kergoat
40. Hervé Bourhy
41. Johan Neyts
42. Leah Soriaga
43. Lisa A. Purcell
44. Gyorgy Snell
45. Sean P.J. Whelan
46. Antonio Lanzavecchia
47. Herbert W. Virgin
48. Luca Piccoli
49. Helen Y. Chu
50. Matteo Samuele Pizzuto
51. Davide Corti
52. David Veesler

Reviewed by ScreenIT

Persistent serum protein signatures define an inflammatory subset of long COVID

1. Aarthi Talla
2. Suhas V. Vasaikar
3. Gregory Lee Szeto
4. Maria P. Lemos
5. Julie L. Czartoski
6. Hugh MacMillan
7. Zoe Moodie
8. Kristen W. Cohen
9. Lamar B. Fleming
10. Zachary Thomson
11. Lauren Okada
12. Lynne A. Becker
13. Ernest M. Coffey
14. Stephen C. De Rosa
15. Evan W. Newell
16. Peter J. Skene
17. Xiaojun Li
18. Thomas F. Bumol
19. M. Juliana McElrath
20. Troy R. Torgerson

Reviewed by ScreenIT

Delayed antigen-specific CD4 ⁺ T-cell induction correlates with impaired immune responses to SARS-COV-2 mRNA vaccination in the elderly

1. Norihide Jo
2. Yu Hidaka
3. Osamu Kikuchi
4. Masaru Fukahori
5. Takeshi Sawada
6. Masahiko Aoki
7. Masaki Yamamoto
8. Miki Nagao
9. Satoshi Morita
10. Takako E Nakajima
11. Manabu Muto
12. Yoko Hamazaki

Reviewed by ScreenIT

Simultaneous and sequential multi-species coronavirus vaccination

1. Lei Peng
2. Zhenhao Fang
3. Paul A. Renauer
4. Andrew McNamara
5. Jonathan J. Park
6. Qianqian Lin
7. Xiaoyu Zhou
8. Matthew B. Dong
9. Biqing Zhu
10. Hongyu Zhao
11. Craig B. Wilen
12. Sidi Chen

Reviewed by ScreenIT

Immunological findings in a group of individuals who were non-responders to standard two-dose SARS-CoV-2 vaccines

1. Qiang Zeng
2. Xue Yang
3. Qi Gao
4. Biao-yang Lin
5. Yong-zhe Li
6. Gang Huang
7. Yang Xu

Reviewed by ScreenIT

Domain fusion TLR2-4 enhances the autophagy-dependent clearance of Staphylococcus aureus in the genetic engineering goat

1. Mengyao Wang
2. Yu Qi
3. Yutao Cao
4. Xiaosheng Zhang
5. Yongsheng Wang
6. Qingyou Liu
7. Jinlong Zhang
8. Guangbin Zhou
9. Yue Ai
10. Shao Wei
11. Linli Wang
12. Guoshi Liu
13. Zhengxing Lian
14. Hongbing Han

• Curated by eLife

  Evaluation Summary:

  This study is of interest to animal geneticists studying molecular breeding for infection resistance. The authors provide substantial new insight into the generation of a goat expressing domain fusion receptor TLR2-4, and clarify the mechanism to effectively eliminate S. aureus in macrophages from the gene-edited goat. Taken together, their findings suggest that TLR2-4 knock-in goats can serve as a good animal model for disease resistance breeding.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #3 agreed to share their name with the authors.)

Reviewed by eLife