Immunology

Daytime variation in SARS-CoV-2 infection and cytokine production

1. Aïssatou Bailo Diallo
2. Laetitia Gay
3. Benjamin Coiffard
4. Marc Leone
5. Soraya Mezouar
6. Jean-Louis Mege

Reviewed by Rapid Reviews Infectious Diseases, ScreenIT

Pre-existing YFV-17D immunity mediates T cell cross-protection against DENV-2 infection

1. Prince Baffour Tonto
2. Sebastian Gallon
3. Reem Alatrash
4. Wei-Kung Wang
5. Bobby Brooke Herrera

Reviewed by Rapid Reviews Infectious Diseases, PREreview

High titers and low fucosylation of early human anti–SARS-CoV-2 IgG promote inflammation by alveolar macrophages

1. Willianne Hoepel
2. Hung-Jen Chen
3. Chiara E. Geyer
4. Sona Allahverdiyeva
5. Xue D. Manz
6. Steven W. de Taeye
7. Jurjan Aman
8. Lynn Mes
9. Maurice Steenhuis
10. Guillermo R. Griffith
11. Peter I. Bonta
12. Philip J.M. Brouwer
13. Tom G. Caniels
14. Karlijn van der Straten
15. Korneliusz Golebski
16. René E. Jonkers
17. Mads D. Larsen
18. Federica Linty
19. Jan Nouta
20. Cindy P.A.A. van Roomen
21. Frank E.H.P. van Baarle
22. Cornelis M. van Drunen
23. Gertjan Wolbink
24. Alexander P.J. Vlaar
25. Godelieve J. de Bree
26. Rogier W. Sanders
27. Lisa Willemsen
28. Annette E. Neele
29. Diederik van de Beek
30. Theo Rispens
31. Manfred Wuhrer
32. Harm Jan Bogaard
33. Marit J. van Gils
34. Gestur Vidarsson
35. Menno de Winther
36. Jeroen den Dunnen

Reviewed by Rapid Reviews Infectious Diseases, ScreenIT, preLights

A conserved immune dysregulation is associated with infection severity, risk factors prior to infection, and treatment response

1. Ananthakrishnan Ganesan
2. Andrew R. Moore
3. Hong Zheng
4. Jiaying Toh
5. Michael Freedman
6. Andrew T. Magis
7. James R. Heath
8. Purvesh Khatri

Reviewed by Rapid Reviews Infectious Diseases

Lipid droplets fuel SARS-CoV-2 replication and production of inflammatory mediators

1. Suelen da Silva Gomes Dias
2. Vinicius Cardoso Soares
3. André C. Ferreira
4. Carolina Q. Sacramento
5. Natalia Fintelman-Rodrigues
6. Jairo R. Temerozo
7. Lívia Teixeira
8. Ester Barreto
9. Mayara Mattos
10. Caroline S. de Freitas
11. Isaclaudia G. Azevedo-Quintanilha
12. Pedro Paulo A. Manso
13. Eugenio D. Hottz
14. Camila R. R. Pão
15. Dumith C. Bou-Habib
16. Fernando A. Bozza
17. Thiago M. L. Souza
18. Patrícia T. Bozza

Reviewed by Rapid Reviews Infectious Diseases, ScreenIT

Dual Role of Glycosylation in Resistance to CD4-binding Site Broadly Neutralizing Antibodies

1. Teresa Murphy
2. Meagan Kelly
3. Kai S. Shimagaki
4. Thomas DeStefanis
5. Gabriel Galeotos
6. Myungjin Lee
7. Qing Wei
8. Jan Novak
9. Katharine J. Bar
10. John P. Barton
11. Rebecca M. Lynch

Reviewed by Rapid Reviews Infectious Diseases

Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV-1 V2 apex broadly neutralizing antibody development

1. Rumi Habib
2. Ryan S. Roark
3. Hui Li
4. Andrew Jesse Connell
5. Michael P. Hogarty
6. Kshitij Wagh
7. Shuyi Wang
8. Lorie Marchitto
9. Ashwin N. Skelly
10. John W. Carey
11. Kirsten J. Sowers
12. Kasirajan Ayyanathan
13. Samantha J. Plante
14. Frederic Bibollet-Ruche
15. Younghoon Park
16. Colby J. Agostino
17. Ajay Singh
18. Christian L. Martella
19. Emily Lewis
20. Juliette M. Rando
21. Neha Chohan
22. Jinery Lora
23. Wenge Ding
24. Mary S. Campion
25. Chengyan Zhao
26. Weimin Liu
27. Yingying Li
28. Xuduo Li
29. Bo Liang
30. Rohan Roy Chowdhury
31. Khaled Amereh
32. Elizabeth Van Itallie
33. Zizhang Sheng
34. Amrit R. Ghosh
35. Katharine J. Bar
36. Wilton B. Williams
37. Kevin Wiehe
38. Kevin O. Saunders
39. Robert J. Edwards
40. Derek W. Cain
41. Mark Lewis
42. Facundo D. Batista
43. Dennis R. Burton
44. Raiees Andrabi
45. Daniel W. Kulp
46. Barton F. Haynes
47. Bette Korber
48. Lawrence Shapiro
49. Peter D. Kwong
50. Beatrice H. Hahn
51. George M. Shaw

Reviewed by Rapid Reviews Infectious Diseases

NK cells undergo transcriptional and functional reprogramming following Streptococcus pneumoniae infection

1. Júlia Torné
2. Claudia Chica
3. Tiphaine Camarasa
4. Bernd Jagla
5. Matilde Diaz Enes
6. Aymeric Zellner
7. Sébastien Mella
8. Valentina Libri
9. Mélanie Anne Hamon

Reviewed by Rapid Reviews Infectious Diseases, PREreview

Alterations in Circulating T-Cell Subsets with Gut-Homing/Residency Phenotypes Predict HIV-1 Status and Subclinical Atherosclerosis

1. Etiene Moreira Gabriel
2. Jonathan Dias
3. Abdelali Filali-Mouhim
4. Ramon Edwin Caballero
5. Tomas Raul Wiche Salinas
6. Manon Nayrac
7. Carl Chartrand-Lefebvre
8. Jean-Pierre Routy
9. Madeleine Durand
10. Mohamed El-Far
11. Cécile Tremblay
12. Petronela Ancuta

Reviewed by Rapid Reviews Infectious Diseases

The 1000+ mouse project for large-scale spatiotemporal parametrization and modeling of preclinical cancer immunotherapies

1. Adam L Kenet
2. Sooraj Achar
3. Alka Dwivedi
4. John Buckley
5. Marie Pouzolles
6. Haying Qin
7. Christopher Chien
8. Naomi Taylor
9. Grégoire Y Altan-Bonnet

• Curated by eLife

  eLife Assessment

  The authors developed a fundamental computational method, which is intended to automatically process bioluminescence imaging-derived tumour images across anatomical regions and over time. This allows quantitative analysis of such data, and the authors applied it to describe the spatiotemporal distribution of tumour cells in response to CD19-targeted CAR-T cells that contained either CD28 or 4-1BB costimulatory domains. Some operational limitations were identified, which relate to the pipeline's reliance on predefined regions of interest instead of aligning signal sites with anatomical information, scaling, and limitations in taking animal pose into account. Overall, the authors provide compelling evidence for the functionality of their computational approach towards automated analysis of bioluminescence imaging data, while applying it to a current topic of wide interest in cell therapy research.

Reviewed by eLife