Immunology

  1. Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants

    1. Matthew McCallum
    2. Alexandra C. Walls
    3. Kaitlin R. Sprouse
    4. John E. Bowen
    5. Laura E. Rosen
    6. Ha V. Dang
    7. Anna De Marco
    8. Nicholas Franko
    9. Sasha W. Tilles
    10. Jennifer Logue
    11. Marcos C. Miranda
    12. Margaret Ahlrichs
    13. Lauren Carter
    14. Gyorgy Snell
    15. Matteo Samuele Pizzuto
    16. Helen Y. Chu
    17. Wesley C. Van Voorhis
    18. Davide Corti
    19. David Veesler

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  2. Optimization of Non-Coding Regions Improves Protective Efficacy of an mRNA SARS-CoV-2 Vaccine in Nonhuman Primates

    1. Makda S. Gebre
    2. Susanne Rauch
    3. Nicole Roth
    4. Jingyou Yu
    5. Abishek Chandrashekar
    6. Noe B. Mercado
    7. Xuan He
    8. Jinyan Liu
    9. Katherine McMahan
    10. Amanda Martinot
    11. Tori Giffin
    12. David Hope
    13. Shivani Patel
    14. Daniel Sellers
    15. Owen Sanborn
    16. Julia Barrett
    17. Xiaowen Liu
    18. Andrew C. Cole
    19. Laurent Pessaint
    20. Daniel Valentin
    21. Zack Flinchbaugh
    22. Jake Yalley-Ogunro
    23. Jeanne Muench
    24. Renita Brown
    25. Anthony Cook
    26. Elyse Teow
    27. Hanne Andersen
    28. Mark G. Lewis
    29. Stefan O. Mueller
    30. Benjamin Petsch
    31. Dan H. Barouch

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  3. Fully Human Antibody Immunoglobulin from Transchromosomic Bovines is Potent Against SARS-CoV-2 Variant Pseudoviruses

    1. Thomas Luke
    2. Hua Wu
    3. Kristi A Egland
    4. Eddie J Sullivan
    5. Christoph L Bausch

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  4. A Single Dose of a Hybrid hAdV5-Based Anti-COVID-19 Vaccine Induces a Long-Lasting Immune Response and Broad Coverage against VOC

    1. M. Verónica López
    2. Sabrina E. Vinzón
    3. Eduardo G. A. Cafferata
    4. Felipe J. Núñez
    5. Ariadna Soto
    6. Maximiliano Sanchez-Lamas
    7. M. Jimena Afonso
    8. Diana Aguilar-Cortes
    9. Gregorio D. Ríos
    10. Juliana T. Maricato
    11. Carla Braconi
    12. Vanessa Silveira
    13. Tatiane Andrad
    14. Tatiana Bonetti
    15. Luiz M. Ramos Janini
    16. Manoel J. B. C. Girão
    17. Andrea S. Llera
    18. Karina A. Gomez
    19. Hugo H. Ortega
    20. Paula M. Berguer
    21. Osvaldo L. Podhajcer

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  5. Conserved T-cell epitopes predicted by bioinformatics in SARS-COV-2 variants

    1. Feiyu Lu
    2. Shengnan Wang
    3. Ying Wang
    4. Yunpeng Yao
    5. Yangeng Wang
    6. Shujun Liu
    7. Yangyang Wang
    8. Yongli Yu
    9. Liying Wang

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  6. SARS-CoV-2 Neutralization in Convalescent Plasma and Commercial Lots of Plasma-Derived Immunoglobulin

    1. Andreas Volk
    2. Caroline Covini-Souris
    3. Denis Kuehnel
    4. Christian De Mey
    5. Jürgen Römisch
    6. Torben Schmidt

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  7. Hybrid immunity improves B cell frequency, antibody potency and breadth against SARS-CoV-2 and variants of concern

    1. Emanuele Andreano
    2. Ida Paciello
    3. Giulia Piccini
    4. Noemi Manganaro
    5. Piero Pileri
    6. Inesa Hyseni
    7. Margherita Leonardi
    8. Elisa Pantano
    9. Valentina Abbiento
    10. Linda Benincasa
    11. Ginevra Giglioli
    12. Concetta De Santi
    13. Massimiliano Fabbiani
    14. Ilaria Rancan
    15. Mario Tumbarello
    16. Francesca Montagnani
    17. Claudia Sala
    18. Emanuele Montomoli
    19. Rino Rappuoli

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  8. Robust and Functional Immune Memory Up to 9 Months After SARS-CoV-2 Infection: A Southeast Asian Longitudinal Cohort

    1. Hoa Thi My Vo
    2. Alvino Maestri
    3. Heidi Auerswald
    4. Sopheak Sorn
    5. Sokchea Lay
    6. Heng Seng
    7. Sotheary Sann
    8. Nisa Ya
    9. Polidy Pean
    10. Philippe Dussart
    11. Olivier Schwartz
    12. Sovann Ly
    13. Timothée Bruel
    14. Sowath Ly
    15. Veasna Duong
    16. Erik A. Karlsson
    17. Tineke Cantaert

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  9. Regulation of positive and negative selection and TCR signaling during thymic T cell development by capicua

    1. Soeun Kim
    2. Guk-Yeol Park
    3. Jong Seok Park
    4. Jiho Park
    5. Hyebeen Hong
    6. Yoontae Lee

    • Curated by eLife

      Evaluation Summary:

      This paper focuses on the transcriptional regulation of the T cell receptor (TCR) signaling cascade and would be of interest to those studying T cell development and differentiation. The authors employ a conditional deletion of the Capicua (Cic) gene, a transcriptional repressor previously shown to be involved in regulating autoimmunity and follicular helper T (Tfh) cell differentiation, and now show that loss of CIC in hematopoietic cells leads to defects in TCR-beta selection as well as in positive and negative selection of developing thymocytes. The overall conclusions are well supported by the findings.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #1 agreed to share their name with the authors.)

    Reviewed by eLife

    4 evaluationsAppears in 1 listLatest version Latest activity

  10. RIG-I-induced innate antiviral immunity protects mice from lethal SARS-CoV-2 infection

    1. Samira Marx
    2. Beate M. Kümmerer
    3. Christian Grützner
    4. Hiroki Kato
    5. Martin Schlee
    6. Marcel Renn
    7. Eva Bartok
    8. Gunther Hartmann

    Reviewed by ScreenIT

    1 evaluationAppears in 2 listsLatest version Latest activity
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