Genomics

  3. Evolutionary remodeling of non-canonical ORF translation in mammals

    1. Yue Chang
    2. Tianyu Lei
    3. Feng Zhou
    4. Jiawen Jiang
    5. Yu Huang
    6. Ziyang Zhu
    7. Hong Zhang

    • Curated by eLife

      eLife Assessment

      This valuable study provides a systematically curated atlas of non-canonical open reading frames translated across normal human and mouse tissues by uniformly integrating nearly 400 ribosome-profiling datasets with independent mass-spectrometry evidence for ncORF-encoded peptides. The convincing analyses connect ncORF evolutionary age and coding constraint with translation level, tissue distribution, and co-translation with canonical coding sequences, offering a broad comparative view of how non-canonical translation changes over mammalian evolution. Although the functions of most ncORF-encoded peptides remain unknown, the scale of their detection across tissues, together with their proteomic and evolutionary signatures, suggests that a substantial subset may have biological functions.

    Reviewed by eLife, Arcadia Science

    12 evaluationsAppears in 2 listsLatest version Latest activity

  4. Crossing host boundaries: the evolutionary drivers and correlates of viral host jumps

    1. Cedric C.S. Tan
    2. Lucy van Dorp
    3. Francois Balloux

    Reviewed by Rapid Reviews Infectious Diseases

    5 evaluationsAppears in 1 listLatest version Latest activity

  7. Paired plus-minus sequencing is an ultra-high throughput and accurate method for dual strand sequencing of DNA molecules

    1. Alexandre Pellan Cheng
    2. Itai Rusinek
    3. Aaron Sossin
    4. Adam J. Widman
    5. Eti Meiri
    6. Gat Krieger
    7. Ori Hirschberg
    8. Doron Shem Tov
    9. Shlomit Gilad
    10. Ariel Jaimovich
    11. Omer Barad
    12. Sammantha Avaylon
    13. Srinivas Rajagopalan
    14. Abigail G. Thress
    15. Catherine Potenski
    16. Tamara Prieto
    17. Dennis J Yuan
    18. Rob Furatero
    19. Alexi Runnels
    20. Benjamin M. Costa
    21. Jonathan E. Shoag
    22. Majd Al Assaad
    23. Michael Sigouros
    24. Jyothi Manohar
    25. Abigail King
    26. David Wilkes
    27. John Otilano
    28. Murtaza S. Malbari
    29. Olivier Elemento
    30. Juan Miguel Mosquera
    31. Nasser K. Altorki
    32. Ashish Saxena
    33. Margaret K. Callahan
    34. Nicolas Robine
    35. Soren Germer
    36. Gilad Evrony
    37. Bishoy M. Faltas
    38. Dan A Landau

    Reviewed by PREreview

    1 evaluationAppears in 1 listLatest version Latest activity

  8. MicroFinder: conserved gene-set mapping and assembly ordering for manual curation of bird dot microchromosomes

    1. Thomas C Mathers
    2. Michael Paulini
    3. Cibele G Sotero-Caio
    4. Jonathan M D Wood

    Reviewed by GigaScience

    2 evaluationsAppears in 1 listLatest version Latest activity

  9. Sex Chromosome Turnover and Structural Interspecific Genome Divergence Shapes Meiotic Outcomes in Hybridizing Cobitis

    1. S. A. Schlebusch
    2. V. Trifonov
    3. Z. Halenková
    4. M. Klianitskaya
    5. D. Dedukh
    6. A. Ruiz Herrera
    7. L. Álvarez González
    8. G. Pujol Infantes
    9. E. Hřibová
    10. L. Andjel
    11. O. Bartoš
    12. P. Pajer
    13. T. Tichopád
    14. D. Kulik
    15. J. Kotusz
    16. M. Kaštánková Doležálková
    17. A. Bohne
    18. A. Marta
    19. P. Horna
    20. R. Reifová
    21. Y. Guiguen
    22. J. Pačes
    23. K. Janko

    Reviewed by GigaScience

    2 evaluationsAppears in 1 listLatest version Latest activity
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