Evolutionary Biology | Sciety

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Minus the Error: Testing for Positive Selection in the Presence of Residual Alignment Errors

This article has 9 authors:
1. Avery Selberg
2. Nathan L Clark
3. Timothy B Sackton
4. Spencer V Muse
5. Alexander G Lucaci
6. Steven Weaver
7. Anton Nekrutenko
8. Maria Chikina
9. Sergei L Kosakovsky Pond
This article has been curated by 1 group:
- Curated by eLife
  
  eLife Assessment
  
  Alignment and sequencing errors are a major concern in molecular evolution, and this valuable study represents a welcome improvement for genome-wide scans of positive selection. This new method seems to perform well and is generally convincing, although the evidence could be made more direct and more complete through additional simulations to determine the extent to which alignment errors are being properly captured.
Reviewed by eLife

This article has 4 evaluationsAppears in 1 listLatest version Jun 26, 2025Latest activity Jun 25, 2025
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