Developmental Biology

Overburdened ferroptotic stress impairs tooth morphogenesis

1. Haisheng Wang
2. Xiaofeng Wang
3. Liuyan Huang
4. Chenglin Wang
5. Fanyuan Yu
6. Ling Ye

• Curated by eLife

  eLife assessment

  This important study time elegantly demonstrates that ferroptotic stress may play critical roles in regulating tooth germ development. The evidence presented is compelling, based on an explant model and providing novel mechanistic insights into tooth development.

Reviewed by eLife

Specific sensory neurons and insulin-like peptides modulate food type-dependent oogenesis and fertilization in Caenorhabditis elegans

1. Shashwat Mishra
2. Mohamed Dabaja
3. Asra Akhlaq
4. Bianca Pereira
5. Kelsey Marbach
6. Mediha Rovcanin
7. Rashmi Chandra
8. Antonio Caballero
9. Diana Fernandes de Abreu
10. QueeLim Ch'ng
11. Joy Alcedo

• Curated by eLife

  eLife assessment

  This work presents useful and potentially valuable findings on how food signals may influence reproduction in the nematode C. elegans. In the current manuscript, the evidence in support of the authors' model is incomplete, and additional experimental data is needed to buttress the authors' conclusions.

Reviewed by eLife

Single-cell RNA sequencing unravels the transcriptional network underlying zebrafish retina regeneration

1. Laura Celotto
2. Fabian Rost
3. Anja Machate
4. Juliane Bläsche
5. Andreas Dahl
6. Anke Weber
7. Stefan Hans
8. Michael Brand

• Curated by eLife

  eLife assessment

  Müller glial cells of the zebrafish retina can differentiate into all neural cell classes following injury, providing full regenerative capabilities of the zebrafish retina. This valuable study presents a description of transcriptional changes of Müller glia cells in the adult and regenerating retina using single-cell RNA sequencing. The overall evidence supporting the main claims of the authors is solid.

Reviewed by eLife

Sperm induction of somatic cell-cell fusion as a novel functional test

1. Nicolas G Brukman
2. Clari Valansi
3. Benjamin Podbilewicz

Reviewed by Review Commons

Molecular basis for positional memory and its reprogrammability in limb regeneration

1. L Otsuki
2. SA Plattner
3. Y Taniguchi-Sugiura
4. EM Tanaka

Reviewed by Arcadia Science

Abnormal behavior is reversible in a chromatin mutant

1. Juan D. Rodriguez
2. Monica N. Reeves
3. Hsiao-Lin V. Wang
4. Jaely Z. Chavez
5. Rhea Rastogi
6. Sindy R. Chavez
7. Elicia A Preston
8. Madhav S. Chadha
9. Liyang Sun
10. Emily J. Hill
11. Victor G. Corces
12. Karen L. Schmeichel
13. John I. Murray
14. David J. Katz

Reviewed by Arcadia Science

Delta-dependent Notch activation closes the early neuroblast temporal program to promote lineage progression and neurogenesis termination in Drosophila

1. Chhavi Sood
2. Md Ausrafuggaman Nahid
3. Kendall R Branham
4. Matt Pahl
5. Susan E Doyle
6. Sarah E Siegrist

• Curated by eLife

  eLife assessment

  This useful study reports on how Notch activity regulates the termination of neurogenesis in central brain during larval-pupal stages in Drosophila. The evidence supporting the claims is solid. The work will be of interest to developmental neurobiologists.

Reviewed by eLife

LincRNAs enable germ cells differentiation by promoting PUF proteins condensation

1. Roni Falk
2. Noa Gilad
3. Hanna Achache
4. Yisrael Rappaport
5. Reut Shabtai
6. Hasan Ishtayeh
7. Laura Wolovelsky
8. Yonatan B. Tzur

Reviewed by preLights

Multiple cis -regulatory elements control prox1a expression in distinct lymphatic vascular beds

1. Virginia Panara
2. Hujun Yu
3. Di Peng
4. Karin Staxäng
5. Monika Hodik
6. Beata Filipek-Gorniok
7. Jan Kazenwadel
8. Renae Skoczylas
9. Elizabeth Mason
10. Amin Allalou
11. Natasha L. Harvey
12. Tatjana Haitina
13. Benjamin M. Hogan
14. Katarzyna Koltowska

Reviewed by Review Commons

Llgl1 mediates timely epicardial emergence and establishment of an apical laminin sheath around the trabeculating cardiac ventricle

1. Eric J. G. Pollitt
2. Juliana Sánchez-Posada
3. Corinna M. Snashall
4. Christopher J. Derrick
5. Emily S. Noël

Reviewed by Review Commons