Developmental Biology

Different cellular and molecular mechanisms of chitin deposition contribute to the specificity of the two chitin synthases in D. melanogaster

1. Joan Bertran-Mas
2. Ettore De Giorgio
3. Nicolás Martín
4. Marta Llimargas

Reviewed by Review Commons

Comparative analysis of the syncytiotrophoblast in placenta tissue and trophoblast organoids using snRNA sequencing

1. Madeline M Keenen
2. Liheng Yang
3. Huan Liang
4. Veronica J Farmer
5. Rizban E Worota
6. Rohit Singh
7. Amy S Gladfelter
8. Carolyn B Coyne

• Curated by eLife

  eLife Assessment

  This important study uses single-cell transcriptomics to analyze syncytiotrophoblasts in two trophoblast organoid models compared to primary placental tissue, providing compelling insights into syncytialization and highlighting the utility of organoid models in placental research. It also serves as an invaluable resource for the field.

Reviewed by eLife

The glycosyltransferase POGLUT1 regulates muscle stem cell development and maintenance in mice

1. Soomin Cho
2. Emilia Servián-Morilla
3. Victoria Navarro Garrido
4. Beatriz Rodriguez-Gonzalez
5. Youxi Yuan
6. Raquel Cano
7. Arjun A. Rambhiya
8. Radbod Darabi
9. Robert S. Haltiwanger
10. Carmen Paradas
11. Hamed Jafar-Nejad

Reviewed by Review Commons

Fat body-derived cytokine Upd2 controls disciplined migration of tracheal stem cells in Drosophila

1. Pengzhen Dong
2. Yue Li
3. Yuying Wang
4. Qiang Zhao
5. Tianfeng Lu
6. Jian Chen
7. Tianyu Guo
8. Jun Ma
9. Bing Yang
10. Honggang Wu
11. Hai Huang

• Curated by eLife

  eLife Assessment

  This valuable study investigates how inter-organ communication between the tracheal stem cells and the fat body plays a key role in the directed migration of tracheal stem cells in Drosophila pupae. The evidence supporting the conclusions is convincing. The work would be of broad interest to researchers in the fields of developmental biology and cancer biology.

Reviewed by eLife

Wnt signaling restores evolutionary loss of regenerative potential in Hydra

1. Sergio E. Campos
2. Sahar Naziri
3. Jackson Crane
4. Jennifer Tsverov
5. Ben D. Cox
6. Craig Ciampa
7. Celina E. Juliano

Reviewed by preLights

CHD3 regulates BMP signalling response during cranial neural crest cell specification

1. Zoe H. Mitchell
2. Joery den Hoed
3. Willemijn Claassen
4. Martina Demurtas
5. Laura Deelen
6. Philippe M. Campeau
7. Karen Liu
8. Simon E. Fisher
9. Marco Trizzino

Reviewed by Review Commons

Coordinated Tbx3/Tbx5 transcriptional control of the adult ventricular conduction system

1. Ozanna Burnicka-Turek
2. Katy A Trampel
3. Brigitte Laforest
4. Michael T Broman
5. Xinan H Yang
6. Zoheb Khan
7. Eric Rytkin
8. Binjie Li
9. Ella Schaffer
10. Margaret Gadek
11. Kaitlyn M Shen
12. Igor R Efimov
13. Ivan P Moskowitz

• Curated by eLife

  eLife Assessment

  The work presented is important for our understanding of the development of the cardiac conduction system and its regulation by T-box transcription factors. The conclusions are supported by convincing data. Overall this is an excellent study that advances our understanding of cardiac biology and has implications beyond the immediate field of study.

Reviewed by eLife

Meioc-Piwil1 complexes regulate rRNA transcription for differentiation of spermatogonial stem cells

1. Toshihiro Kawasaki
2. Toshiya Nishimura
3. Naoki Tani
4. Carina Ramos
5. Emil Karaulanov
6. Minori Shinya
7. Kenji Saito
8. Emily Taylor
9. René F Ketting
10. Kei-ichiro Ishiguro
11. Minoru Tanaka
12. Kellee R Siegfried
13. Noriyoshi Sakai

• Curated by eLife

  eLife Assessment

  This important paper describes the regulatory pathway of rRNA synthesis by Meioc-Piwil1 in germ cell differentiation in zebrafish. Using the molecular genetic and cytological approaches, the authors provide convincing evidence that Meioc antagonizes Piwil1, which downregulates the 45S pre-rRNA synthesis by heterochromatin formation for spermatocyte differentiation. The results will be of use to researchers in the field of germ cell/meiosis as well as RNA biosynthesis and chromatin.

Reviewed by eLife

Spectral decomposition unlocks ascidian morphogenesis

1. Joel Dokmegang
2. Emmanuel Faure
3. Patrick Lemaire
4. Edwin Munro
5. Madhav Mani

• Curated by eLife

  eLife Assessment

  In this important work, a quantitative analysis method for three-dimensional morphogenetic processes during embryonic development is introduced. The proposed method is a pipeline combining several methods, allowing quantitative analysis of developmental processes without cell segmentation and tracking. Upon application of their method, the authors obtain convincing evidence that ascidian gastrulation is a two-step process. This work should be of interest to a broad range of developmental biologists who aim to obtain a quantitative understanding of morphogenesis.

Reviewed by eLife

A low-level Cdkn1c/p57 ^kip2 expression in spinal progenitors drives the transition from proliferative to neurogenic modes of division

1. Baptiste Mida
2. Nathalie Lehman
3. Fanny Coulpier
4. Kamal Bouhali
5. Rosette Goiame
6. Morgane Thomas-Chollier
7. Evelyne Fischer
8. Xavier Morin

Reviewed by Review Commons