Developmental Biology

E(spl)m4 Directly Antagonizes Traf4 to Inhibit JNK Signaling in Drosophila

1. Katrin Strobel
2. Jennifer Falconi
3. Cédric Leyrat
4. Rémi Logeay
5. Sarah J Bray
6. Alexandre Djiane

• Curated by eLife

  eLife Assessment

  The authors identify the Bearded-type small protein E(spl)m4 as a physical and genetic interactor of TRAF4 in the Drosophila wing disc. These valuable findings with potential biomedical relevance are, however, supported by incomplete evidence based largely on overexpression studies that lack quantification, limited molecular support for their model, and issues with Bearded family protein specificity. The work could be of interest to researchers in the fields of cell signaling and developmental biology.

Reviewed by eLife

Genome-wide association study shows developmental robustness control by intestinal maltase via internal environment in Drosophila

1. Soshiro Kashio
2. Izumi Enoki
3. Yuto Yoshinari
4. Takashi Nishimura
5. Masayuki Miura

Reviewed by Review Commons

VANGL2 shapes the mouse heart tube from adjacent epithelia and without planar polarity

1. Paul Palmquist-Gomes
2. Gaëlle Letort
3. Ayushi U. Hegde
4. José María Pérez-Pomares
5. Sigolène M. Meilhac

Reviewed by preLights

Dissecting gene regulatory networks governing human cortical cell fate

1. Jingwen W. Ding
2. Chang N. Kim
3. Megan S. Ostrowski
4. Yashodara Abeykoon
5. Bryan J. Pavlovic
6. Jenelle L. Wallace
7. Nathan K. Schaefer
8. Tomasz J. Nowakowski
9. Alex A. Pollen

Reviewed by preLights

Complementary Volume Electron Microscopy-based approaches reveal ultrastructural changes in germline intercellular bridges of D. melanogaster

1. Irina Kolotuev
2. Abigayle Williams
3. Caroline Kizilyaprak
4. Stephanie Pellegrino
5. Lindsay Lewellyn

Reviewed by Review Commons

Getting a head start: Craniofacial heterochrony in marsupials involves dynamic changes to molecular and cellular mechanisms underlying neural crest development

1. Axel H Newton
2. Ella R Farley
3. Andrew T Major
4. Jennifer C Hutchison
5. Ben M Lawrence
6. Karen E Sears
7. Marilyn B Renfree
8. Aiden M C Couzens
9. Geoff Shaw
10. Sara Ord
11. Richard A Schneider
12. Andrew J Pask

Reviewed by preLights