Cell Biology

Single-cell atlas of a non-human primate reveals new pathogenic mechanisms of COVID-19

1. Lei Han
2. Xiaoyu Wei
3. Chuanyu Liu
4. Giacomo Volpe
5. Zhifeng Wang
6. Taotao Pan
7. Yue Yuan
8. Ying Lei
9. Yiwei Lai
10. Carl Ward
11. Yeya Yu
12. Mingyue Wang
13. Quan Shi
14. Tao Wu
15. Liang Wu
16. Ya Liu
17. Chunqing Wang
18. Yuanhang Zhang
19. Haixi Sun
20. Hao Yu
21. Zhenkun Zhuang
22. Tingting Tang
23. Yunting Huang
24. Haorong Lu
25. Liqin Xu
26. Jiangshan Xu
27. Mengnan Cheng
28. Yang Liu
29. Chi Wai Wong
30. Tao Tan
31. Weizhi Ji
32. Patrick H. Maxwell
33. Huanming Yang
34. Jian Wang
35. Shida Zhu
36. Shiping Liu
37. Xun Xu
38. Yong Hou
39. Miguel A. Esteban
40. Longqi Liu
41. South China Greater Bay Area-Single Cell Consortium (SC-GBA-C)

Reviewed by ScreenIT

Computational search of hybrid human/ SARS-CoV-2 dsRNA reveals unique viral sequences that diverge from those of other coronavirus strains

1. Claude Pasquier
2. Alain Robichon

Reviewed by ScreenIT

The protein expression profile of ACE2 in human tissues

1. Feria Hikmet
2. Loren Méar
3. Åsa Edvinsson
4. Patrick Micke
5. Mathias Uhlén
6. Cecilia Lindskog

Reviewed by ScreenIT

Cigarette smoke exposure and inflammatory signaling increase the expression of the SARS-CoV-2 receptor ACE2 in the respiratory tract

1. Joan C. Smith
2. Erin L. Sausville
3. Vishruth Girish
4. Monet Lou Yuan
5. Kristen M. John
6. Jason M. Sheltzer

Reviewed by ScreenIT

The Nucleocapsid Protein of SARS-CoV-2 Abolished Pluripotency in Human Induced Pluripotent Stem Cells

1. Zebin Lin
2. Zhiming Wu
3. Jinlian Mai
4. Lishi Zhou
5. Yu Qian
6. Tian Cai
7. Zhenhua Chen
8. Ping Wang
9. Bin Lin

Reviewed by ScreenIT

Recapitulation of SARS-CoV-2 Infection and Cholangiocyte Damage with Human Liver Organoids

1. Bing Zhao
2. Chao Ni
3. Ran Gao
4. Yuyan Wang
5. Li Yang
6. Jinsong Wei
7. Ting Lv
8. Jianqing Liang
9. Qisheng Zhang
10. Wei Xu
11. Youhua Xie
12. Xiaoyue Wang
13. Zhenghong Yuan
14. Junbo Liang
15. Rong Zhang
16. Xinhua Lin

Reviewed by ScreenIT

Kinetochore-fiber lengths are maintained locally but coordinated globally by poles in the mammalian spindle

1. Manuela Richter
2. Lila Neahring
3. Jinghui Tao
4. Renaldo Sutanto
5. Nathan H Cho
6. Sophie Dumont

• Curated by eLife

  eLife assessment

  The authors compellingly demonstrate that k-fiber length and dynamics are regulated at the level of individual fibers, even in the absence of focused poles, but that unfocused spindles fail to accurately segregate chromosomes, suggesting that coordination of k-fiber length by pole focusing is important for spindle function. This study provides important new information on spindle scaling, extending in an original manner previous work on this topic.

Reviewed by eLife

Metformin regulates bone marrow stromal cells to accelerate bone healing in diabetic mice

1. Yuqi Guo
2. Jianlu Wei
3. Chuanju Liu
4. Xin Li
5. Wenbo Yan

• Curated by eLife

  eLife assessment

  This fundamental work advances our understanding of the effects of metformin on bone healing in hyperglycemic conditions. The evidence supporting the conclusion is convincing, using three different types of bone fracture models in type-2 diabetes (T2D) mice. This paper is of potential interest to skeletal biologists, orthopaedic surgeons, and endocrinologists who study the effects of metformin on fracture healing.

Reviewed by eLife

Bitesize bundles F-actin and influences actin remodeling in syncytial Drosophila embryo development

1. Anna R. Yeh
2. Gregory J. Hoeprich
3. Anthony McDougal
4. Bruce L. Goode
5. Adam C. Martin

Reviewed by Review Commons

A simple Turing reaction-diffusion model can explain how mother centrioles break symmetry to generate a single daughter

1. Zachary M. Wilmott
2. Alain Goriely
3. Jordan W. Raff

Reviewed by Review Commons