Cell Biology

  1. A scalable, data analytics workflow for image-based morphological profiles

    1. Edvin Forsgren
    2. Olivier Cloarec
    3. Pär Jonsson
    4. Gillian Lovell
    5. Johan Trygg

    Reviewed by Arcadia Science

    3 evaluationsAppears in 1 listLatest version Latest activity

  2. Actin contraction controls nuclear blebbing and rupture independent of actin confinement

    1. Mai Pho
    2. Yasmin Berrada
    3. Aachal Gunda
    4. Anya Lavallee
    5. Katherine Chiu
    6. Arimita Padam
    7. Marilena L. Currey
    8. Andrew D. Stephens

    Reviewed by Review Commons

    5 evaluationsAppears in 1 listLatest version Latest activity

  3. SUMOylation of ABCD3 restricts bile acid synthesis and regulates metabolic homeostasis

    1. Vanessa Goyon
    2. Aurèle Besse-Patin
    3. Rodolfo Zunino
    4. Mai Nguyen
    5. Étienne Coyaud
    6. Jonathan M. Lee
    7. Bich N. Nguyen
    8. Brian Raught
    9. Heidi M. McBride

    Reviewed by Review Commons

    4 evaluationsAppears in 1 listLatest version Latest activity

  4. Removal of extracellular human amyloid beta aggregates by extracellular proteases in C. elegans

    1. Elisabeth Jongsma
    2. Anita Goyala
    3. José Maria Mateos
    4. Collin Yvès Ewald

    • Curated by eLife

      eLife assessment

      Using a newly developed C. elegans model of Alzheimer's disease that expresses Abeta aggregates extracellularly, the authors provide convincing evidence of a disintegrin and an ortholog of human ADAM9 that participate in removing these extracellular aggregates. The worm model presented in this important paper may be very useful to the Alzheimer Disease field.

    Reviewed by eLife

    5 evaluationsAppears in 2 listsLatest version Latest activity

  5. The kleisin subunit controls the function of C. elegans meiotic cohesins by determining the mode of DNA binding and differential regulation by SCC-2 and WAPL-1

    1. Maikel Castellano-Pozo
    2. Georgios Sioutas
    3. Consuelo Barroso
    4. Josh P Prince
    5. Pablo Lopez-Jimenez
    6. Joseph Davy
    7. Angel-Luis Jaso-Tamame
    8. Oliver Crawley
    9. Nan Shao
    10. Jesus Page
    11. Enrique Martinez-Perez

    • Curated by eLife

      eLife assessment

      This important paper reveals distinct dynamics of two meiosis-specific cohesin complexes containing either REC-8 or CHO-3/4 in C. elegans: REC-8-cohesin is essential for sister chromatid cohesion in meiosis I and DNA double-strand break repair, while COH-3/4-cohesin, whose binding to meiotic chromosomes is stabilized by the cohesin accessory protein SCC-2, is necessary for loop-axis formation. The experimental evidence in the paper is solid based on cytological analysis using a conditional depletion of the gene. The work will be of interest to researchers working on meiosis and chromosome dynamics.

    Reviewed by eLife

    5 evaluationsAppears in 1 listLatest version Latest activity

  6. Centriole elimination during C. elegans oogenesis initiates with loss of the central tube protein SAS-1

    1. Marie Pierron
    2. Alexander Woglar
    3. Coralie Busso
    4. Keshav Jha
    5. Tamara Mikeladze-Dvali
    6. Marie Croisier
    7. Pierre Gönczy

    Reviewed by Review Commons

    4 evaluationsAppears in 1 listLatest version Latest activity

  7. CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis

    1. Avi J. Samelson
    2. Nabeela Ariqat
    3. Justin McKetney
    4. Gita Rohanitazangi
    5. Celeste Parra Bravo
    6. Rudra Bose
    7. Kyle J. Travaglini
    8. Victor L. Lam
    9. Darrin Goodness
    10. Gary Dixon
    11. Emily Marzette
    12. Julianne Jin
    13. Ruilin Tian
    14. Eric Tse
    15. Romany Abskharon
    16. Henry Pan
    17. Emma C. Carroll
    18. Rosalie E. Lawrence
    19. Jason E. Gestwicki
    20. Jessica E. Rexach
    21. David Eisenberg
    22. Nicholas M. Kanaan
    23. Daniel R. Southworth
    24. John D. Gross
    25. Li Gan
    26. Danielle L. Swaney
    27. Martin Kampmann

    Reviewed by preLights

    1 evaluationAppears in 1 listLatest version Latest activity

  8. Robust three-dimensional expansion of human adult alveolar stem cells and SARS-CoV-2 infection

    1. Jeonghwan Youk
    2. Taewoo Kim
    3. Kelly V. Evans
    4. Young-Il Jeong
    5. Yongsuk Hur
    6. Seon Pyo Hong
    7. Je Hyoung Kim
    8. Kijong Yi
    9. Su Yeon Kim
    10. Kwon Joong Na
    11. Thomas Bleazard
    12. Ho Min Kim
    13. Natasha Ivory
    14. Krishnaa T. Mahbubani
    15. Kourosh Saeb-Parsy
    16. Young Tae Kim
    17. Gou Young Koh
    18. Byeong-Sun Choi
    19. Young Seok Ju
    20. Joo-Hyeon Lee

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  9. Identification of cell lines CL-14, CL-40 and CAL-51 as suitable models for SARS-CoV-2 infection studies

    1. Claudia Pommerenke
    2. Ulfert Rand
    3. Cord C. Uphoff
    4. Stefan Nagel
    5. Margarete Zaborski
    6. Vivien Hauer
    7. Maren Kaufmann
    8. Corinna Meyer
    9. Sabine A. Denkmann
    10. Peggy Riese
    11. Kathrin Eschke
    12. Yeonsu Kim
    13. Zeljka Macak Safranko
    14. Ivan-Christian Kurolt
    15. Alemka Markotic
    16. Luka Cicin-Sain
    17. Laura Steenpass

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  10. Genes Encoding ACE2, TMPRSS2 and Related Proteins Mediating SARS-CoV-2 Viral Entry are Upregulated with Age in Human Cardiomyocytes

    1. Emma L. Robinson
    2. Kanar Alkass
    3. Olaf Bergmann
    4. Janet J. Maguire
    5. H. Llewelyn Roderick
    6. Anthony P. Davenport

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity
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