Cell Biology

Caspase-mediated nuclear pore complex trimming in cell differentiation and endoplasmic reticulum stress

1. Ukrae H Cho
2. Martin W Hetzer

• Curated by eLife

  eLife assessment

  This important study outlines a new role for caspases during cellular differentiation. The methodology used is convincing and state-of-the-art. The newly discovered cellular cascade described here uncovers that caspases can achieve high substrate specificity during differentiation. As such, the work will be of broad interest to cell biologists.

Reviewed by eLife

The maintenance of centriole appendages and motile cilia basal body anchoring relies on TBCCD1

1. Bruno Carmona
2. Carolina Camelo
3. Manon Mehraz
4. Michel Lemullois
5. Mariana Lince Faria
6. Étienne Coyaud
7. H. Susana Marinho
8. João Gonçalves
9. Sofia Nolasco
10. Francisco Pinto
11. Brian Raught
12. Anne-Marie Tassin
13. France Koll
14. Helena Soares

Reviewed by Arcadia Science

CryoET shows cofilactin filaments inside the microtubule lumen

1. Camilla Ventura Santos
2. Stephen L. Rogers
3. Andrew P. Carter

Reviewed by Arcadia Science

Cooperative Motility, Force Generation and Mechanosensing in a Foraging Non-Photosynthetic Diatom

1. Peng Zheng
2. Kayo Kumadaki
3. Christopher Quek
4. Zeng Hao Lim
5. Yonatan Ashenafi
6. Zhi Ting Yip
7. Jay Newby
8. Andrew J. Alverson
9. Yan Jie
10. Gregory Jedd

Reviewed by Arcadia Science

Single-cell intracellular pH dynamics regulate the cell cycle by timing the G1 exit and G2 transition

1. Julia S. Spear
2. Katharine A. White

Reviewed by Arcadia Science, ASAPbio crowd review

Tunnelling nanotube formation is driven by Eps8/IRSp53‐dependent linear actin polymerization

1. J Michael Henderson
2. Nina Ljubojevic
3. Sevan Belian
4. Thibault Chaze
5. Daryl Castaneda
6. Aude Battistella
7. Quentin Giai Gianetto
8. Mariette Matondo
9. Stéphanie Descroix
10. Patricia Bassereau
11. Chiara Zurzolo

Reviewed by Arcadia Science, Review Commons

Targeted volume correlative light and electron microscopy of an environmental marine microorganism

1. Karel Mocaer
2. Giulia Mizzon
3. Manuel Gunkel
4. Aliaksandr Halavatyi
5. Anna Steyer
6. Viola Oorschot
7. Martin Schorb
8. Charlotte Le Kieffre
9. Daniel P. Yee
10. Fabien Chevalier
11. Benoit Gallet
12. Johan Decelle
13. Yannick Schwab
14. Paolo Ronchi

Reviewed by Review Commons, Arcadia Science

Cooperative actin filament nucleation by the Arp2/3 complex and formins maintains the homeostatic cortical array in Arabidopsis epidermal cells

1. Liyuan Xu
2. Lingyan Cao
3. Jiejie Li
4. Christopher J Staiger

Reviewed by Arcadia Science

ERK3/MAPK6 dictates CDC42/RAC1 activity and ARP2/3-dependent actin polymerization

1. Katarzyna Bogucka-Janczi
2. Gregory Harms
3. Marie-May Coissieux
4. Mohamed Bentires-Alj
5. Bernd Thiede
6. Krishnaraj Rajalingam

• Curated by eLife

  eLife assessment

  The manuscript describes a fundamental study of the atypical MAPK, ERK3, in the activation of RhoGTPase Cdc42 and the formation of actin-rich protrusions and cell migration. The results show that ERK3 is required for the motility of tumor cells in vivo, providing a new target for fighting metastasis.

Reviewed by Arcadia Science, eLife

CLASP2 facilitates dynamic actin filament organization along the microtubule lattice

1. N. C. Rodgers
2. E. J. Lawrence
3. A. V. Sawant
4. N. Efimova
5. G. Gonzalez-Vasquez
6. T. T. Hickman
7. I. Kaverina
8. M. Zanic

Reviewed by Arcadia Science