Biophysics

Role of RNA Guanine Quadruplexes in Favoring the Dimerization of SARS Unique Domain in Coronaviruses

1. Cécilia Hognon
2. Tom Miclot
3. Cristina Garcı́a-Iriepa
4. Antonio Francés-Monerris
5. Stephanie Grandemange
6. Alessio Terenzi
7. Marco Marazzi
8. Giampaolo Barone
9. Antonio Monari

Reviewed by ScreenIT

On the interactions of the receptor-binding domain of SARS-CoV-1 and SARS-CoV-2 spike proteins with monoclonal antibodies and the receptor ACE2

1. Carolina Corrêa Giron
2. Aatto Laaksonen
3. Fernando L. Barroso da Silva

Reviewed by ScreenIT

Biophysical characterization of the SARS-CoV-2 spike protein binding with the ACE2 receptor and implications for infectivity

1. Ratul Chowdhury
2. Costas D. Maranas

Reviewed by ScreenIT

In-Silico Evidence for a Two Receptor Based Strategy of SARS-CoV-2

1. Edoardo Milanetti
2. Mattia Miotto
3. Lorenzo Di Rienzo
4. Madhu Nagaraj
5. Michele Monti
6. Thaddeus W. Golbek
7. Giorgio Gosti
8. Steven J. Roeters
9. Tobias Weidner
10. Daniel E. Otzen
11. Giancarlo Ruocco

Reviewed by ScreenIT

Computational simulations reveal the binding dynamics between human ACE2 and the receptor binding domain of SARS‐CoV‐2 spike protein

1. Cecylia S. Lupala
2. Xuanxuan Li
3. Jian Lei
4. Hong Chen
5. Jianxun Qi
6. Haiguang Liu
7. Xiao‐Dong Su

Reviewed by ScreenIT

Identify potent SARS-CoV-2 main protease inhibitors via accelerated free energy perturbation-based virtual screening of existing drugs

1. Zhe Li
2. Xin Li
3. Yi-You Huang
4. Yaoxing Wu
5. Runduo Liu
6. Lingli Zhou
7. Yuxi Lin
8. Deyan Wu
9. Lei Zhang
10. Hao Liu
11. Ximing Xu
12. Kunqian Yu
13. Yuxia Zhang
14. Jun Cui
15. Chang-Guo Zhan
16. Xin Wang
17. Hai-Bin Luo

Reviewed by ScreenIT

A Multiscale and Comparative Model for Receptor Binding of 2019 Novel Coronavirus and the Implication of its Life Cycle in Host Cells

1. Zhaoqian Su
2. Yinghao Wu

Reviewed by ScreenIT

Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor

1. Jun Lan
2. Jiwan Ge
3. Jinfang Yu
4. Sisi Shan
5. Huan Zhou
6. Shilong Fan
7. Qi Zhang
8. Xuanling Shi
9. Qisheng Wang
10. Linqi Zhang
11. Xinquan Wang

Reviewed by ScreenIT

Structure and Immune Recognition of the Porcine Epidemic Diarrhea Virus Spike Protein

1. Robert Kirchdoerfer

Reviewed by ScreenIT

Spontaneous body wall contractions stabilize the fluid microenvironment that shapes host–microbe associations

1. Janna C Nawroth
2. Christoph Giez
3. Alexander Klimovich
4. Eva Kanso
5. Thomas CG Bosch

• Curated by eLife

  eLife assessment

  This important work studies the spontaneous contractions (SC) of the Hydra body wall and presents a mathematical model of nutrient transport to hypothesize the role of SC on maintaining the microbiota. The solid evidence presented yields insights on the functional implications of the SC and the increased nutrient update obtained from mixing the local fluid environment through body wall contractions. The main result represents an important observation about the role of hydrodynamics on organism behavior and its relation to diffusive chemical transport processes.

Reviewed by eLife