Bioinformatics

Integrated single-dose kinome profiling data is predictive of cancer cell line sensitivity to kinase inhibitors

1. Chinmaya U. Joisa
2. Kevin A. Chen
3. Matthew E. Berginski
4. Brian T. Golitz
5. Madison R. Jenner
6. Gabriela Herrera Loeza
7. Jen Jen Yeh
8. Shawn M. Gomez

Reviewed by PeerJ

Integrated genomics provides insights for the evolution of the polyphosphate accumulation trait of Ca. Accumulibacter

1. Xiaojing Xie
2. Xuhan Deng
3. Liping Chen
4. Jing Yuan
5. Hang Chen
6. Chaohai Wei
7. Xianghui Liu
8. Stefan Wuertz
9. Guanglei Qiu

Reviewed by Arcadia Science

Reprogramming of cardiac phosphoproteome, proteome, and transcriptome confers resilience to chronic adenylyl cyclase-driven stress

1. Jia-Hua Qu
2. Khalid Chakir
3. Kirill V Tarasov
4. Daniel R Riordon
5. Maria Grazia Perino
6. Allwin Jennifa Silvester
7. Edward G Lakatta

• Curated by eLife

  eLife assessment

  This study describes important results from cardiac-specific overexpression of adenylyl cyclase type 8 (TGAC8) mice that was integrated with transcriptomic and proteomic evidence. The paper convincingly provides new insights into how one can interpret signals from visceral organs.

Reviewed by eLife

cellsnake: a user-friendly tool for single-cell RNA sequencing analysis

1. Sinan U. Umu
2. Karoline Rapp Vander-Elst
3. Victoria T. Karlsen
4. Manto Chouliara
5. Espen Sønderaal Bækkevold
6. Frode Lars Jahnsen
7. Diana Domanska

Reviewed by GigaScience

SpheroScan: A User-Friendly Deep Learning Tool for Spheroid Image Analysis

1. Akshay Akshay
2. Mitali Katoch
3. Masoud Abedi
4. Mustafa Besic
5. Navid Shekarchizadeh
6. Fiona C. Burkhard
7. Alex Bigger-Allen
8. Rosalyn M. Adam
9. Katia Monastyrskaya
10. Ali Hashemi Gheinani

Reviewed by GigaScience

Developing best practices for genotyping-by-sequencing analysis in the construction of linkage maps

1. Cristiane Hayumi Taniguti
2. Lucas Mitsuo Taniguti
3. Rodrigo Rampazo Amadeu
4. Jeekin Lau
5. Gabriel de Siqueira Gesteira
6. Thiago de Paula Oliveira
7. Getulio Caixeta Ferreira
8. Guilherme da Silva Pereira
9. David Byrne
10. Marcelo Mollinari
11. Oscar Riera-Lizarazu
12. Antonio Augusto Franco Garcia

Reviewed by GigaScience

Computational prediction of human deep intronic variation

1. Pedro Barbosa
2. Rosina Savisaar
3. Maria Carmo-Fonseca
4. Alcides Fonseca

Reviewed by GigaScience

Charting cellular differentiation trajectories with Ricci flow

1. Anthony Baptista
2. Ben D. MacArthur
3. Christopher R. S. Banerji

Reviewed by Review Commons

Fast, lightweight, and accurate metagenomic functional profiling using FracMinHash sketches

1. Mahmudur Rahman Hera
2. Shaopeng Liu
3. Wei Wei
4. Judith S. Rodriguez
5. Chunyu Ma
6. David Koslicki

Reviewed by Arcadia Science

Cross-Dataset Identification of Human Disease-Specific Cell Subtypes Enabled by the Gene Print-based Algorithm--gPRINT

1. Ruojin Yan
2. Chunmei Fan
3. Shen Gu
4. Tingzhang Wang
5. Zi Yin
6. Xiao CHEN

Reviewed by Arcadia Science