Evaluated articles

InteracTor: A new integrative feature extraction toolkit for improved characterization of protein structural properties

1. Jose Cleydson F. Silva
2. Layla Schuster
3. Nick Sexson
4. Matias Kirst
5. Marcio F. R. Resende
6. Raquel Dias

Reviewed by Arcadia Science

Evaluation of tick salivary and midgut extracellular vesicles as anti-tick vaccines in White-tailed deer (Odocoileus virginianus)

1. Julia Gonzalez
2. Cristina Harvey
3. Cárita de Souza Ribeiro-Silva
4. Brenda Leal-Galvan
5. Kelly A. Persinger
6. Pia U. Olafson
7. Tammi L. Johnson
8. Adela Oliva Chavez

Reviewed by Arcadia Science

Unveiling the functional connectivity of astrocytic networks with AstroNet, a graph reconstruction algorithm coupled to image processing

1. L. Zonca
2. F. C. Bellier
3. G. Milior
4. P. Aymard
5. J. Visser
6. A. Rancillac
7. N. Rouach
8. D. Holcman

Reviewed by Arcadia Science

Trim7 does not have a role in the restriction of murine norovirus infection in vivo

1. Mridula Annaswamy Srinivas
2. Linley R. Pierce
3. Mikayla C. Olson
4. Shelly J. Roberston
5. Gail L. Sturdevant
6. Sonja M. Best
7. Robert C. Orchard

Reviewed by Arcadia Science

Mast cells promote pathology and susceptibility in tuberculosis

1. Ananya Gupta
2. Vibha Taneja
3. Javier Rangel Moreno
4. Abhimanyu
5. Mushtaq Ahmed
6. Nilofer Naqvi
7. Kuldeep S Chauhan
8. Daniela Trejo-Ponce de León
9. Gustavo Ramírez-Martínez
10. Luis Jiménez-Alvarez
11. Cesar Luna-Rivero
12. Joaquin Zuniga
13. Deepak Kaushal
14. Shabaana A Khader

• Curated by eLife

  eLife Assessment

  In this useful study, the authors use published scRNA-seq data to highlight the importance of mast cells (MCs) in TB granulomas, reporting a comparative assessment of chymase- and tryptase-expressing MCs in the lungs of tuberculosis-infected individuals and non-human primates, with MC-deficient mice showing reduced lung bacterial burden and pathology during infection. Whilst the findings are helpful, the evidence to support conclusions is inconsistent across models and thus incomplete. Specifically, the data supporting a role for MCs in coordinating cytokine responses to modulate pathology, susceptibility to tuberculosis, and dissemination during infection are weak.

Reviewed by eLife, Arcadia Science

Population genomics reveals strong impacts of genetic drift without purging and guides conservation of bull and giant kelp

1. Jordan B. Bemmels
2. Samuel Starko
3. Brooke L. Weigel
4. Kaede Hirabayashi
5. Alex Pinch
6. Cassandra Elphinstone
7. Megan N. Dethier
8. Loren H. Rieseberg
9. Jonathan E. Page
10. Christopher J. Neufeld
11. Gregory L. Owens

Reviewed by Arcadia Science

Cigarette smoke impairs the endocytotic process in Saccharomyces cerevisiae

1. Aditya Shukla
2. Srimonti Sarkar
3. Alok Kumar Sil

Reviewed by Arcadia Science

BFVD—a large repository of predicted viral protein structures

1. Rachel Seongeun Kim
2. Eli Levy Karin
3. Milot Mirdita
4. Rayan Chikhi
5. Martin Steinegger

Reviewed by Arcadia Science

Mechanical Centrosome Fracturing during Cell Navigation

1. Madeleine T. Schmitt
2. Mauricio J.A. Ruiz-Fernandez
3. Kasia Stefanowski
4. Janina Kroll
5. Robert Hauschild
6. Jack Merrin
7. Thomas Penz
8. Eva Kiermaier
9. Christoph Bock
10. Tobias Straub
11. Jörg Renkawitz

Reviewed by Arcadia Science

An automated microfluidic platform for toxicity testing based on Caenorhabditis elegans

1. Jiaying Wu
2. Jing Xi
3. Zhouhai Zhu
4. Wei Zhao
5. Qiyuan Peng
6. Chunbo Liu
7. Ziqian Wan
8. Yiyi Cao
9. Xiang Chen
10. Yang Luan

Reviewed by Arcadia Science

Reduced gravity and muon radiation affect Caenorhabditis elegans life history traits and viral infection

1. Ana Villena-Giménez
2. Victoria G. Castiglioni
3. Juan C. Muñoz-Sánchez
4. Esmeralda G. Legarda
5. Rubén González
6. Santiago F. Elena

Reviewed by Arcadia Science

Intestinal helminth skews DC2 development towards regulatory phenotype to counter the anti-helminth immune response

1. Anna Andrusaite
2. Olivia Ridgewell
3. Anna Ahlback
4. Holly Webster
5. Hiroki Yamaguchi
6. Molly Peel
7. Annika Frede
8. Sarwah Al-Khalidi
9. Andrew Farthing
10. Anna Heawood
11. Annabelle Smith
12. Edward Roberts
13. Allan Mowat
14. Richard Maizels
15. Georgia Perona-Wright
16. Simon Milling

Reviewed by Arcadia Science

Dimensionality reduction of genetic data using contrastive learning

1. Filip Thor
2. Carl Nettelblad

Reviewed by Arcadia Science

Evolutionary trends in the emergence of skeletal cell types

1. Amor Damatac
2. Sara Koska
3. Kristian K Ullrich
4. Tomislav Domazet-Lošo
5. Alexander Klimovich
6. Markéta Kaucká

Reviewed by Arcadia Science

Quantitative Comparison of Monomeric StayGold Variants Using Protein Nanocages in Living Cells

1. Giulia Viola
2. Kyle A. Jacobs
3. Joël Lemière
4. Matthew L. Kutys
5. Torsten Wittmann

Reviewed by Arcadia Science

A novel channel invariant architecture for the segmentation of cells and nuclei in multiplexed images using InstanSeg

1. Thibaut Goldsborough
2. Alan O’Callaghan
3. Fiona Inglis
4. Léo Leplat
5. Andrew Filby
6. Hakan Bilen
7. Peter Bankhead

Reviewed by Arcadia Science

Functional Diversification of Gene Duplicates under the Constraint of Protein Structure

1. Kangning Guo
2. Yuqing Yang
3. Tingting You
4. Kangli Zhu

Reviewed by Arcadia Science

Opening the species box: what parsimonious microscopic models of speciation have to say about macroevolution

1. Élisa Couvert
2. François Bienvenu
3. Jean-Jil Duchamps
4. Adélie Erard
5. Verónica Miró Pina
6. Emmanuel Schertzer
7. Amaury Lambert

Reviewed by Arcadia Science

Exploring breast cancer-related biochemical changes in circulating extracellular vesicles using Raman spectroscopy

1. Arianna Bonizzi
2. Lorena Signati
3. Maria Grimaldi
4. Marta Truffi
5. Francesca Piccotti
6. Stella Gagliardi
7. Giulia Dotti
8. Serena Mazzucchelli
9. Sara Albasini
10. Roberta Cazzola
11. Debanjan Bhowmik
12. Chandrabhas Narayana
13. Fabio Corsi
14. Carlo Morasso

Reviewed by Arcadia Science

Morphology-based classification of sickle cell disease and β-thalassemia using a low-cost automated microscope and machine learning

1. Pranav Shrestha
2. Hendrik Lohse
3. Christopher Bhatla
4. Heather McCartney
5. Alaa Alzaki
6. Navdeep Sandhu
7. Pradip Kumar Oli
8. Hongquan Li
9. Manu Prakash
10. Ali Amid
11. Rodrigo Onell
12. Nicholas Au
13. Hayley Merkeley
14. Videsh Kapoor
15. Rajan Pande
16. Boris Stoeber

Reviewed by Arcadia Science