Evaluated articles

Two-Photon Targeted, Quad Whole-Cell Patch-Clamping Robot

1. Gema I Vera Gonzalez
2. Phatsimo O Kgwarae
3. Simon R Schultz

Reviewed by Arcadia Science

Capitella teleta gets left out: Possible evolutionary shift causes loss of left tissues rather than increased neural tissue from dominant-negative BMPR1

1. Nicole B. Webster
2. Néva P. Meyer

Reviewed by Arcadia Science

Bsp1, a fungal CPI motif protein, regulates actin filament capping in endocytosis and cytokinesis

1. Daniel R. Hummel
2. Markku Hakala
3. Christopher P. Toret
4. Marko Kaksonen

Reviewed by Arcadia Science

The embryonic role of juvenile hormone in the firebrat, Thermobia domestica, reveals its function before its involvement in metamorphosis

1. James W Truman
2. Lynn M Riddiford
3. Barbora Konopova
4. Marcela Nouzova
5. Fernando G Noriega
6. Michelle Herko

• Curated by eLife

  eLife assessment

  This important study presents findings regarding the role of Juvenile Hormone in development and cell differentiation in the ametabolous insect Thermobia domestica, providing an in-depth analysis of JH's roles in a member of this basally branching group. The evidence supporting the claims of the authors is convincing, drawing on a broad range of approaches and variety of experimental techniques. While the interpretation of this work in the wider context - its relevance for the evolution of metamorphosis - is in some places somewhat speculative, the work will be of interest to evolutionary developmental biologists studying the evolution of metamorphosis, and the evolution of insects in general.

Reviewed by eLife, Arcadia Science

A phylogenetic method linking nucleotide substitution rates to rates of continuous trait evolution

1. Patrick Gemmell
2. Timothy B. Sackton
3. Scott V. Edwards
4. Jun S. Liu

Reviewed by Arcadia Science

Deep-learning-enabled antibiotic discovery through molecular de-extinction

1. Fangping Wan
2. Marcelo D. T. Torres
3. Jacqueline Peng
4. Cesar de la Fuente-Nunez

Reviewed by Arcadia Science

The commensal protist Tritrichomonas musculus exhibits a dynamic life cycle that induces extensive remodeling of the gut microbiota

1. Ana Popovic
2. Eric Yixiao Cao
3. Joanna Han
4. Nirvana Nursimulu
5. Eliza V.C. Alves-Ferreira
6. Kyle Burrows
7. Andrea Kennard
8. Noor Alsmadi
9. Michael E. Grigg
10. Arthur Mortha
11. John Parkinson

Reviewed by Arcadia Science

Discovery of a new activator of Slack potassium channels with robust efficacy in models of histamine-independent and chronic itch

1. Annika Balzulat
2. W. Felix Zhu
3. Cathrin Flauaus
4. Victor Hernandez-Olmos
5. Jan Heering
6. Sunesh Sethumadhavan
7. Mariam Dubiel
8. Annika Frank
9. Amelie Menge
10. Maureen Hebchen
11. Katharina Metzner
12. Ruirui Lu
13. Robert Lukowski
14. Peter Ruth
15. Stefan Knapp
16. Susanne Müller
17. Dieter Steinhilber
18. Inga Hänelt
19. Holger Stark
20. Ewgenij Proschak
21. Achim Schmidtko

Reviewed by Arcadia Science

Diverse prey capture strategies in teleost larvae

1. Duncan S Mearns
2. Sydney A Hunt
3. Martin W Schneider
4. Ash V Parker
5. Manuel Stemmer
6. Herwig Baier

• Curated by eLife

  eLife Assessment

  This important body of work uses state-of-the-art quantitative methods to characterize and compare behaviors across five different fish species to understand which features are conserved and which ones are differentiated. The convincing results from this study will be of interest to ethologists and also have potential utility in understanding the neural mechanisms leading to these behaviors.

Reviewed by eLife, Arcadia Science

Diverse signatures of convergent evolution in cacti-associated yeasts

1. Carla Gonçalves
2. Marie-Claire Harrison
3. Jacob L. Steenwyk
4. Dana A. Opulente
5. Abigail L. LaBella
6. John F. Wolters
7. Xiaofan Zhou
8. Xing-Xing Shen
9. Marizeth Groenewald
10. Chris Todd Hittinger
11. Antonis Rokas

Reviewed by Arcadia Science

Structure of a tripartite protein complex that targets toxins to the type VII secretion system

1. Timothy A. Klein
2. Prakhar Y. Shah
3. Polyniki Gkragkopoulou
4. Dirk W. Grebenc
5. Youngchang Kim
6. John C. Whitney

Reviewed by Arcadia Science

Single-shot quantitative phase imaging with polarization differential interference contrast

1. Mark Strassberg
2. Yana Shevtsova
3. Domenick Kamel
4. Kai Wagoner-Oshima
5. Hualin Zhong
6. Min Xu

Reviewed by Arcadia Science

A metagenomics pipeline reveals insertion sequence-driven evolution of the microbiota

1. Joshua M. Kirsch
2. Andrew J. Hryckowian
3. Breck A. Duerkop

Reviewed by Arcadia Science

Engineered Active Zymogen of Microbial Transglutaminase

1. Ryutaro Ariyoshi
2. Takashi Matsuzaki
3. Ryo Sato
4. Kosuke Minamihata
5. Kounosuke Hayashi
6. Rie Wakabayashi
7. Masahiro Goto
8. Noriho Kamiya

Reviewed by Arcadia Science

Identification of a convergent spinal neuron population that encodes itch

1. Tayler D. Sheahan
2. Charles A. Warwick
3. Abby Y. Cui
4. David A.A. Baranger
5. Vijay J. Perry
6. Kelly M. Smith
7. Allison P. Manalo
8. Eileen K. Nguyen
9. H. Richard Koerber
10. Sarah E. Ross

Reviewed by Arcadia Science

Single-cell analysis of psoriasis resolution reveals an inflammatory fibroblast state targeted by IL-23 blockade

1. Luc Francis
2. Daniel McCluskey
3. Clarisse Ganier
4. Treasa Jiang
5. Xinyi Du-Harpur
6. Jeyrroy Gabriel
7. Pawan Dhami
8. Yogesh Kamra
9. Sudha Visvanathan
10. Jonathan N. Barker
11. Catherine H. Smith
12. Francesca Capon
13. Satveer K. Mahil

Reviewed by Arcadia Science

Longitudinal Associations Between Mild Behavioral Impairment, Sleep Disturbance, and Progression to Dementia

1. Dinithi Mudalige
2. Dylan X. Guan
3. Maryam Ghahremani
4. Zahinoor Ismail

Reviewed by Arcadia Science

Evolutionary prediction for new echolocators

1. Qi Liu
2. Qin-Yang Hua
3. Rui Sun
4. Shui-Wang He
5. Meng-Cheng Li
6. Lu-Ye Shi
7. Peng Chen
8. Yuan-Shuo Ma
9. Qin Zhang
10. Xue-Long Jiang
11. Yong Wang
12. Peng Shi

Reviewed by Arcadia Science

Divergent evolution of sleep functions

1. Michaela Joyce
2. Federica A. Falconio
3. Laurence Blackhurst
4. Lucia Prieto-Godino
5. Alice S. French
6. Giorgio F. Gilestro

Reviewed by Arcadia Science

Modular control of vertebrate axis segmentation in time and space

1. Ali Seleit
2. Ian Brettell
3. Tomas Fitzgerald
4. Carina Vibe
5. Felix Loosli
6. Joachim Wittbrodt
7. Kiyoshi Naruse
8. Ewan Birney
9. Alexander Aulehla

Reviewed by preLights, Review Commons, Arcadia Science