Evaluated articles

G6b-B antibody-based cis-acting platelet receptor inhibitors (CAPRIs) as a new family of anti-thrombotic therapeutics

1. Alexandra Mazharian
2. Ophélie Bertin
3. Amrita Sarkar
4. Johanna Augros
5. Alicia Bornert
6. Cécile Loubière
7. Friederike Jönsson
8. Juli Warwicker
9. W Mark Abbott
10. Omer Dushek
11. Caroline Vayne
12. Lubica Rauova
13. Klaus Fütterer
14. Jérôme Rollin
15. Mortimer Poncz
16. Yotis A Senis

Reviewed by preLights

LINC complex alterations are a hallmark of sporadic and familial ALS/FTD

1. Riccardo Sirtori
2. Michelle Gregoire
3. Emily Potts
4. Alicia Collins
5. Liviana Donatelli
6. Claudia Fallini

Reviewed by preLights

Characterization of natural product inhibitors of quorum sensing in Pseudomonas aeruginosa reveals competitive inhibition of RhlR by ortho -vanillin

1. Kathryn E. Woods
2. Sana Akhter
3. Blanca Rodriguez
4. Kade A. Townsend
5. Nathan Smith
6. Ben Smith
7. Alice Wambua
8. Vaughn Craddock
9. Rhea G. Abisado-Duque
10. Emma E. Santa
11. Daniel E. Manson
12. Berl R. Oakley
13. Lynn E. Hancock
14. Yinglong Miao
15. Helen E. Blackwell
16. Josephine R. Chandler

Reviewed by preLights

Feedback loop regulation between viperin and viral hemorrhagic septicemia virus through competing protein degradation pathways

1. Xiaobing Lu
2. Meisheng Yi
3. Zhe Hu
4. Taoran Yang
5. Wanwan Zhang
6. E. Neil G. Marsh
7. Kuntong Jia

Reviewed by preLights

Lytic bacteriophages interact with respiratory epithelial cells and induce the secretion of antiviral and proinflammatory cytokines

1. Paula F. Zamora
2. Thomas G. Reidy
3. Catherine R. Armbruster
4. Ming Sun
5. Daria Van Tyne
6. Paul E. Turner
7. Jonathan L. Koff
8. Jennifer M. Bomberger

Reviewed by preLights

Experts fail to reliably detect AI-generated histological data

1. Jan Hartung
2. Stefanie Reuter
3. Vera Anna Kulow
4. Michael Fähling
5. Cord Spreckelsen
6. Ralf Mrowka

Reviewed by preLights

Mitochondria-derived nuclear ATP surge protects against confinement-induced proliferation defects

1. Ritobrata Ghose
2. Fabio Pezzano
3. Savvas Kourtis
4. Ilir Sheraj
5. Shubhamay Das
6. Antoni Gañez Zapater
7. Upamanyu Ghose
8. Lorena Espinar
9. Katja Parapatics
10. Valeria Venturini
11. André C Müller
12. Verena Ruprecht
13. Sara Sdelci

Reviewed by preLights

Streptococcus pneumoniae augments circadian clock gene expression in zebrafish cells

1. Camila Morales Fénero
2. Raina E. Sacksteder
3. Jacqueline M. Kimmey

Reviewed by preLights

Scientific civility and academic performance

1. Emma Camacho
2. Quigly Dragotakes
3. Isabella Hartshorn
4. Arturo Casadevall
5. Daniel L Buccino

Reviewed by preLights

PPARγ mediated enhanced lipid biogenesis fuels Mycobacterium tuberculosis growth in a drug-tolerant hepatocyte environment

1. Binayak Sarkar
2. Jyotsna Singh
3. Mohit Yadav
4. Priya Sharma
5. Raman Deep Sharma
6. Shweta Singh
7. Aakash Chandramouli
8. Kritee Mehdiratta
9. Ashwani Kumar
10. Siddhesh S Kamat
11. Devram S Ghorpade
12. Debasisa Mohanty
13. Dhiraj Kumar
14. Rajesh S Gokhale

• Curated by eLife

  eLife Assessment

  This fundamental study examines infection of the liver and hepatocytes during Mycobacterium tuberculosis infection using different systems including aerosol infection of mice and guinea pigs to demonstrate appreciable infection of the liver as well as the lung. The authors present convincing evidence that hepatocyte infection leads to metabolic dysfunction that promotes M. tuberculosis growth, in part potentially mediated by a nuclear receptor called PPARg. Overall, this is an interesting paper on an area of tuberculosis research which has been understudied, representing a significant advancement in the field.

Reviewed by eLife, preLights

Finding the right words to evaluate research: An empirical appraisal of eLife’s assessment vocabulary

1. Tom E. Hardwicke
2. Sarah R. Schiavone
3. Beth Clarke
4. Simine Vazire

Reviewed by preLights

Aspergillus dsRNA virus drives fungal fitness and pathogenicity in the mammalian host

1. Marina Campos Rocha
2. Vanda Lerer
3. John Adeoye
4. Hilla Hayby
5. Maria Laura Fabre
6. Amelia E. Barber
7. Neta Shlezinger

Reviewed by preLights

Lipid-Based Transfection of Zebrafish Embryos: A Robust Protocol for Nucleic Acid Delivery in Zebrafish

1. Aslihan Terzi
2. Tiger Lao
3. Adrian Jacobo

Reviewed by preLights

Topology changes of the regenerating Hydra define actin nematic defects as mechanical organizers of morphogenesis

1. Yamini Ravichandran
2. Matthias Vogg
3. Karsten Kruse
4. Daniel JG Pearce
5. Aurélien Roux

Reviewed by Arcadia Science, preLights

Stoichiometric 14-3-3ζ binding promotes phospho-Tau microtubule dissociation and reduces aggregation and condensation

1. Janine Hochmair
2. Maxime C. M. van den Oetelaar
3. Leandre Ravatt
4. Lisa Diez
5. Lenne J. M. Lemmens
6. Renata Ponce-Lina
7. Rithika Sankar
8. Maximilian Franck
9. Gesa Nolte
10. Ekaterina Semenova
11. Satabdee Mohapatra
12. Christian Ottmann
13. Luc Brunsveld
14. Susanne Wegmann

Reviewed by preLights

Blue appendages and temperature acclimation increase survival during acute heat stress in the upside-down jellyfish, Cassiopea xamachana

1. Megan E. Maloney
2. Katherine M. Buckley
3. Marie E. Strader

Reviewed by preLights

Fetal brain response to maternal inflammation requires microglia

1. Bridget Elaine LaMonica Ostrem
2. Nuria Dominguez Iturza
3. Jeffrey Stogsdill
4. Tyler Faits
5. Kwanho Kim
6. Joshua Z. Levin
7. Paola Arlotta

Reviewed by preLights

Alteration of long and short-term hematopoietic stem cell ratio causes myeloid-biased hematopoiesis

1. Katsuyuki Nishi
2. Taro Sakamaki
3. Akiomi Nagasaka
4. Kevin S. Kao
5. Kay Sadaoka
6. Masahide Asano
7. Nobuyuki Yamamoto
8. Akifumi Takaori-Kondo
9. Masanori Miyanishi

• Curated by eLife

  eLife Assessment

  The manuscript provides useful findings to explore the heterogeneity of hematopoietic stem cells and age-related myeloid-biased hematopoiesis. The results presented in this study are incomplete and additional data are necessary to bolster the conclusions. Certain aspects of the methods, experimental design, and data analyses remain inadequate and only partially support the central claims.

Reviewed by eLife, preLights

How the liver contributes to stomach warming in the endothermic white shark Carcharodon carcharias

1. David C. Bernvi
2. Geremy Cliff

Reviewed by preLights

Expressive modeling and fast simulation for dynamic compartments

1. Till Köster
2. Philipp Henning
3. Tom Warnke
4. Adelinde Uhrmacher

Reviewed by preLights