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  1. Digitize your Biology! Modeling multicellular systems through interpretable cell behavior

    This article has 35 authors:
    1. Jeanette A.I. Johnson
    2. Genevieve L. Stein-O’Brien
    3. Max Booth
    4. Randy Heiland
    5. Furkan Kurtoglu
    6. Daniel R. Bergman
    7. Elmar Bucher
    8. Atul Deshpande
    9. André Forjaz
    10. Michael Getz
    11. Ines Godet
    12. Melissa Lyman
    13. John Metzcar
    14. Jacob Mitchell
    15. Andrew Raddatz
    16. Heber Rocha
    17. Jacobo Solorzano
    18. Aneequa Sundus
    19. Yafei Wang
    20. Danielle Gilkes
    21. Luciane T. Kagohara
    22. Ashley L. Kiemen
    23. Elizabeth D. Thompson
    24. Denis Wirtz
    25. Pei-Hsun Wu
    26. Neeha Zaidi
    27. Lei Zheng
    28. Jacquelyn W. Zimmerman
    29. Elizabeth M. Jaffee
    30. Young Hwan Chang
    31. Lisa M. Coussens
    32. Joe W. Gray
    33. Laura M. Heiser
    34. Elana J. Fertig
    35. Paul Macklin

    Reviewed by preLights

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  2. Effects of Aerobic Exercise in Hepatic Lipid Droplet-Mitochondria interaction in Non-alcoholic Fatty Liver Disease

    This article has 13 authors:
    1. Juan Carlos BĂłrquez
    2. Francisco DĂ­az-Castro
    3. Francisco Pino-de La Fuente
    4. Karla Espinoza
    5. Ana MarĂ­a Figueroa
    6. Inma MartĂ­nez-RuĂ­z
    7. Vanessa Hernández
    8. Iliana LĂłpez-Soldado
    9. RaĂşl Ventura
    10. Alejandra Espinosa
    11. Víctor Cortés
    12. María Isabel Hernández-Alvarez
    13. Rodrigo Troncoso

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  3. NAD+ metabolism is a key modulator of bacterial respiratory epithelial infections

    This article has 23 authors:
    1. Björn Klabunde
    2. André Wesener
    3. Wilhelm Bertrams
    4. Isabell Beinborn
    5. Nicole Paczia
    6. Kristin Surmann
    7. Sascha Blankenburg
    8. Jochen Wilhelm
    9. Javier Serrania
    10. Kèvin Knoops
    11. Eslam M. Elsayed
    12. Katrin Laakmann
    13. Anna Lena Jung
    14. Andreas Kirschbaum
    15. Sven Hammerschmidt
    16. Belal Alshaar
    17. Nicolas Gisch
    18. Mobarak Abu Mraheil
    19. Anke Becker
    20. Uwe Völker
    21. Evelyn Vollmeister
    22. Birke J. Benedikter
    23. Bernd Schmeck

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  4. The genome of the colonial hydroid Hydractinia reveals their stem cells utilize a toolkit of evolutionarily shared genes with all animals

    This article has 29 authors:
    1. Christine E. Schnitzler
    2. E. Sally Chang
    3. Justin Waletich
    4. Gonzalo Quiroga-Artigas
    5. Wai Yee Wong
    6. Anh-Dao Nguyen
    7. Sofia N. Barreira
    8. Liam Doonan
    9. Paul Gonzalez
    10. Sergey Koren
    11. James M. Gahan
    12. Steven M. Sanders
    13. Brian Bradshaw
    14. Timothy Q. DuBuc
    15. Febrimarsa
    16. Danielle de Jong
    17. Eric P. Nawrocki
    18. Alexandra Larson
    19. Samantha Klasfeld
    20. Sebastian G. Gornik
    21. R. Travis Moreland
    22. Tyra G. Wolfsberg
    23. Adam M. Phillippy
    24. James C. Mullikin
    25. Oleg Simakov
    26. Paulyn Cartwright
    27. Matthew Nicotra
    28. Uri Frank
    29. Andreas D. Baxevanis

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  5. TLR2 regulates hair follicle cycle and regeneration via BMP signaling

    This article has 10 authors:
    1. Luyang Xiong
    2. Irina Zhevlakova
    3. Xiaoxia Z West
    4. Detao Gao
    5. Rakhilya Murtazina
    6. Anthony Horak
    7. J Mark Brown
    8. Iuliia Molokotina
    9. Eugene A Podrez
    10. Tatiana V Byzova
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      Toll like receptor 2 (TLR2) signaling has traditionally been viewed a surface protein that induces innate immune responses and improves acquired immunity. Here, the authors suggest a different role for TLR2 in the hair cycle. By using a Cre reporter that is largely, but not solely active in hair follicle stem cells, the authors conditionally delete Tlr2 in mice and report that BMP signaling is sustained and hair cycle entry is delayed. Delving further, the authors identify CEP (2-ω-carboxyethyl pyrrole) as an endogenous ligand of TLR2 in hair follicle stem cell regulation. Although a role for TLR2 signaling in hair follicle stem cells is potentially novel and important, the reviewers remain in consensus that evidence presented in two significant areas continues to be incomplete: 1) where TLR2 and CEP are expressed and how specific is their expression to the hair follicle stem cells; 2) whether as the authors suggest, TLR2 functions by regulating BMP signaling in the stem cell niche of the hair follicle.

    Reviewed by eLife, preLights

    This article has 7 evaluationsAppears in 3 listsLatest version Latest activity
  6. Optical Control of G-Actin with a Photoswitchable Latrunculin

    This article has 10 authors:
    1. Nynke A. Vepřek
    2. Madeline H. Cooper
    3. Laura Laprell
    4. Emily Jie-Ning Yang
    5. Sander Folkerts
    6. Ruiyang Bao
    7. Thomas G. Oertner
    8. Liza A. Pon
    9. J. Bradley Zuchero
    10. Dirk H. Trauner

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  7. Mechano-dependent sorbitol accumulation supports biomolecular condensate

    This article has 16 authors:
    1. Stephanie Torrino
    2. William M Oldham
    3. Andrés R Tejedor
    4. Ignacio S. Burgos
    5. Nesrine Rachedi
    6. KĂ©ren Fraissard
    7. Caroline Chauvet
    8. Chaima Sbai
    9. Brendan P. O’Hara
    10. Sophie Abélanet
    11. Frederic Brau
    12. Stephan Clavel
    13. Rosana Collepardo-Guevara
    14. Jorge R. Espinosa
    15. Issam Ben-Sahra
    16. Thomas Bertero

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