Evaluated articles

Inhibition of VP2-mediated entry: a potential antiviral strategy to treat or prevent calicivirus disease

1. Charlotte B. Lewis
2. Lee Sherry
3. Rochelle McGrory
4. Eibhlin Gould
5. Millie Freitag
6. Hagar Sasvari
7. June Southall
8. Filip Petrov
9. Amit Meir
10. Nithya Govindan
11. Andrea Spiri
12. Matteo Bordicchia
13. Regina Hofmann-Lehmann
14. Vanessa R. Barrs
15. Joe Grove
16. Andrew G. Jamieson
17. Margaret J. Hosie
18. David Bhella

Reviewed by preLights

Behavioral characteristics of an extremely old rhesus macaque in a zoo: Dementia-like symptoms and implications for quality of life of geriatric animals

1. Yumi Yamanashi
2. Haruna Bando
3. Keita Niimi
4. Daisuke Nakagawa
5. Susumu Iwaide
6. Tomoaki Murakami

Reviewed by preLights

Targeting CXADR-mediated AKT signaling suppresses tumorigenesis and enhances chemotherapy efficacy in Ewing sarcoma

1. Alina Ritter
2. Malenka Zimmermann
3. Florian H. Geyer
4. Pablo Táboas
5. David Obermeier
6. Martha J. Carreño Gonzalez
7. Kimberley M. Hanssen
8. Tobias Faehling
9. Jana Siebenlist
10. Annika Jeschke
11. Laura Romero-Pérez
12. Roland Imle
13. Ana Banito
14. Enrique de Álava
15. Wolfgang Hartmann
16. Uta Dirksen
17. Thomas G. P. Grünewald
18. Florencia Cidre-Aranaz

Reviewed by preLights

CENP-B binds hairpin motifs in chromosome arms influencing gene expression

1. Lillian Wu
2. Karen A Lane
3. Reyhan Muhammad
4. Alison Harrod
5. Catherine Naughton
6. Hefei Wang
7. Andrea Musacchio
8. Nick Gilbert
9. Claudio Alfieri
10. Jessica A Downs

Reviewed by preLights

The Endocannabinoid System’s Contribution to Placebo Analgesia

1. Rossi Tomin
2. Kevin Murray
3. Georgia E. Hadjis
4. Omar Khalil
5. Christine Sexton
6. Stephanie L. Bourke
7. James S. Khan
8. David P. Finn
9. Lauren Y. Atlas
10. Massieh Moayedi

Reviewed by preLights

EBV reprograms autoreactive anti-CNS B cells as antigen presenting cells in multiple sclerosis

1. Shady Younis
2. Sajede Rasouli
3. Jacob W. Loeffler
4. Neda Sattarnezhad
5. Ya’el Courtney
6. Salvinaz I. Moutusy
7. Shaghayegh Jahanbani
8. Mahesh Pandit
9. Anna Tomczak
10. Heidi H. Wong
11. Orr Sharpe
12. Paul J. Utz
13. Eric Meffre
14. Lucas B. Kipp
15. Jeffrey E. Dunn
16. Tobias V. Lanz
17. Lawrence Steinman
18. William H. Robinson

Reviewed by preLights

Clinically reported covert cerebrovascular disease and risk of neurological disease: a whole-population cohort of 367,988 people using natural language processing

1. Matthew H Iveson
2. Mome Mukerjee
3. Emma M Davidson
4. Huayu Zhang
5. Laura Sherlock
6. Emily L Ball
7. Grant Mair
8. Alice Hosking
9. Heather Whalley
10. Michael T C Poon
11. Joanna M Wardlaw
12. David Kent
13. Richard Tobin
14. Claire Grover
15. Beatrice Alex
16. William N Whiteley

Reviewed by preLights

Dual inhibition of GTP-bound (ON) and GDP-bound (OFF) KRAS ^G12C suppresses PI3Kα and leads to potent tumor inhibition

1. Katherine Parker
2. Samar Ghorbanpoor
3. Wafa Malik
4. Lauren Highfield
5. Jamie Wang
6. Emily Hensley
7. Grace Kelley
8. Sarah Clark
9. Michela Ranieri
10. Soumyadip Sahu
11. Cathy Zhang
12. Magdalena Ploszaj
13. Daniel Andrussier
14. Hsin-Yi Huang
15. Ting Chen
16. Bin Wang
17. Rui Xu
18. Saman Setoodeh
19. Ken Lin
20. Anna E. Maciag
21. Frank McCormick
22. Pedro J. Beltran
23. Kwok-Kin Wong
24. James P. Stice
25. Kerstin W. Sinkevicius
26. Aaron N. Hata

Reviewed by preLights

Deep Invaginations of Nuclear Envelope Coordinate Spatial Organization of Chromatin in Epithelium

1. Elina Mäntylä
2. Sanna Korpela
3. Anna Rekonen
4. Sini Hakkola
5. Jenni Karttunen
6. Anni Pörsti
7. Sanni Erämies
8. Fábio Tadeu Arrojo Martins
9. Roselia Davidsson
10. Markus J.T. Ojanen
11. Satu A-M. Hakanen
12. Peipei Wang
13. Joonas Uusi-Mäkelä
14. Alice Anais Varlet
15. Maija Vihinen-Ranta
16. Daniel E. Conway
17. Keijo Viiri
18. Matti Nykter
19. Jan Lammerding
20. Teemu O. Ihalainen

Reviewed by preLights

Ribosome Molecular Aging Shapes Translation Dynamics

1. Jordy F. Botello
2. Lifei Jiang
3. Peter J. Metzger
4. Troy J. Comi
5. Aya A. Abu-Alfa
6. Qiwei Yu
7. Margaret S. Ebert
8. Minkyu Lee
9. Lennard W. Wiesner
10. Maya Butani
11. Claire J. Weaver
12. Andrej Košmrlj
13. Ileana M. Cristea
14. Clifford P. Brangwynne

Reviewed by preLights

Inhibition of the gut ceramidase Asah2 decelerates the vertebrate ageing rate

1. Ayami Takaochi
2. Kota Abe
3. Yuki Sugiura
4. Akane Kawaguchi
5. Shigehiro Kuraku
6. Hide-Nori Tanaka
7. Daisuke Motooka
8. Kaori Tanaka
9. Farzana Ferdousi
10. Masao Nagasaki
11. Yasuyuki Ohkawa
12. Tohru Ishitani

Reviewed by preLights

A Cell Size-Dependent Competition Between Geometry and Polarity Governs Nuclear and Spindle positioning in Early Embryos

1. Aude Nommick
2. Macy Baboch
3. Celia Municio-Diaz
4. Jeremy Sallé
5. Remi Le Borgne
6. Nicolas Minc

Reviewed by preLights

Zygotic genome activation is timed by the egg DNA-to-cytoplasm ratio across animals

1. Israel Campo-Bes
2. Federica Mantica
3. Jon Permanyer
4. Cristina Rodriguez-Marin
5. Kero Guynes
6. Tot Senar-Serra
7. Gonzalo Quiroga-Artigas
8. Yan Liang
9. Allan M. Carrillo-Baltodano
10. Josefa Cruz
11. Rossella Annunziata
12. Sandra Chevalier
13. Marta Iglesias
14. Fumiaki Sugahara
15. Yi-Jyun Luo
16. Anna Schoenauer
17. Jorge Corbacho
18. Periklis Paganos
19. Filomena Caccavale
20. Rosa Maria Sepe
21. Luis P. Iniguez
22. Mette Handberg-Thorsager
23. Christina Zakas
24. Ralf J. Sommer
25. Maria Ina Arnone
26. Alistair P. McGregor
27. Juan R. Martinez-Morales
28. Noriyuki Satoh
29. Hector Escriva
30. Stephanie Bertrand
31. Arnau Sebe-Pedros
32. Enrico D'Aniello
33. Juan Pascual-Anaya
34. Evelyn Houliston
35. Xavier Franch-Marro
36. David Martin
37. Ildiko M.L. Somorjai
38. Isabel Almudi
39. Jose M. Martin-Duran
40. Yi-Hsien Su
41. Alejandro Burga
42. Salvatore D'Aniello
43. Manuel Irimia

Reviewed by preLights

Mechanically-induced Septin Networks Protect Nuclear Integrity

1. Margaret E. Utgaard
2. Alexia Caillier
3. Shreya Chandrasekar
4. Joseph J. Tidei
5. Harikrushnan Balasubramanian
6. Rachel M. Lee
7. Owen Puls
8. Satya Khuon
9. Jesse Aaron
10. Teng-Leong Chew
11. Jordan R. Beach
12. Patrick W. Oakes

Reviewed by preLights

Feeding and reproduction of a tropical coastal copepod across warming and copper gradients

1. Ngoc-Anh Vu
2. Minh-Hoang Le
3. Tuan-Anh Hoang Lu
4. Hoang Viet Luu
5. Nam X. Doan
6. Kiem N. Truong
7. Khuong V. Dinh

Reviewed by preLights

Heatwave winners and losers: cryptic coral holobionts differ in thermal tolerance

1. Zoe Meziere
2. Ilha Byrne
3. Iva Popovic
4. Andrew Khalil
5. Adriana Humanes
6. James Guest
7. Cheong Xin Chan
8. Cynthia Riginos
9. Katrina McGuigan

Reviewed by preLights

Chromatin priming and co-factor availability shape lineage response to the neuronal pioneer factor ASCL1 in pluripotency

1. Jethro Lundie-Brown
2. Rosalind Drummond
3. John-Poul Ng-Blichfeldt
4. Roberta Azzarelli
5. Anna Philpott

Reviewed by preLights

Generalization and extinction of learned fear alter primary sensory input to the brain

1. Michelle C. Rosenthal
2. Alper K. Bakir
3. John P. McGann

Reviewed by preLights

Fear conditioning biases olfactory sensory neuron frequencies across generations

1. Clara W Liff
2. Yasmine R Ayman
3. Eliza CB Jaeger
4. Avery Cardeiro
5. Hudson S Lee
6. Alexis Kim
7. Angelica Vina-Abarracin
8. Dianne-Lee KD Ferguson
9. Bianca J Marlin

• Curated by eLife

  eLife Assessment

  This study provides solid evidence that odor fear conditioning biases olfactory sensory neuron receptor choice in mice and that this bias is detectable in the next generation. The authors use rigorous histological and behavioral analyses, including unsupervised behavioral quantification, to support the conclusion that odor-specific sensory representations can be shaped by experience and partially transmitted across generations. While the behavioral effects in offspring are modest and the mechanistic basis of inheritance remains unresolved, the study offers an important and carefully executed contribution to understanding experience-dependent sensory plasticity and its intergenerational consequences.

Reviewed by preLights, eLife

Temporal degradation of PRC2 uncovers specific developmental dependencies

1. Ming-Kang Lee
2. Sebastian D. Mackowiak
3. Daniel Felismino
4. Jeron Venhuizen
5. Maria Walther
6. Alexander Meissner

Reviewed by preLights