Evaluated articles

An experimental test of the influence of microbial manipulation on sugar kelp ( Saccharina latissima ) supports the the core influences host function hypothesis

1. Jungsoo Park
2. Evan Kohn
3. Siobhan Schenk
4. Katherine Davis
5. Jennifer Clark
6. Laura Wegener Parfrey

Reviewed by preLights

Unexpected mechanisms of sex-specific memory vulnerabilities to acute traumatic stress

1. Rachael E. Hokenson
2. Kiara L. Rodríguez-Acevedo
3. Yuncai Chen
4. Annabel K. Short
5. Sara A. Samrari
6. Brinda Devireddy
7. Brittany J. Jensen
8. Julia J. Winter
9. Christine M. Gall
10. Kiran K. Soma
11. Elizabeth A. Heller
12. Tallie Z. Baram

Reviewed by preLights

Tooth development in frogs: Implications for the re-evolution of lost mandibular teeth and the origin of a morphological innovation

1. Daniel J. Paluh
2. Madeline Brinkman
3. Kyliah Gilliam-Beale
4. Daniela Salcedo-Recio
5. Jacob Szafranski
6. James Hanken
7. Gareth J. Fraser

Reviewed by preLights

TDP-43 directly inhibits RNA accumulation in neurites through modulation of RNA stability

1. Charlie Moffatt
2. Ankita Arora
3. Katherine F. Vaeth
4. Bryan B. Guzman
5. Gurprit Bhardwaj
6. Audrey Hoelscher
7. Levi B. Gifford
8. Holger A. Russ
9. Daniel Dominguez
10. J. Matthew Taliaferro

Reviewed by preLights

Prenatal exposure to environmental stressors alters gut macrophage development and gastrointestinal function of male offspring

1. Dang M. Nguyen
2. Sarah K. Monroe
3. Danielle N. Rendina
4. Kevin S. Boyd
5. Erika D. Rispoli
6. Olivia M. Wirfel
7. A. Brayan Campos-Salazar
8. Anna R. Araujo
9. Trisha V. Vaidyanathan
10. Virginia L. Keziah
11. Benjamin A. Devlin
12. Caroline J. Smith
13. Staci D. Bilbo

Reviewed by preLights

Chronic stress antagonizes formation of Stress Granules

1. Yuichiro Adachi
2. Allison M. Williams
3. Masashi Masuda
4. Yutaka Taketani
5. Paul J. Anderson
6. Pavel Ivanov

Reviewed by preLights

Evolution of taste processing shifts dietary preference

1. Enrico Bertolini
2. Daniel Münch
3. Justine Pascual
4. Noemi Sgammeglia
5. Carlos Ribeiro
6. Thomas O. Auer

Reviewed by preLights

Inferring protein from mRNA concentrations using convolutional neural networks

1. Patrick Maximilian Schwehn
2. Pascal Falter-Braun

Reviewed by preLights

Invasion of glioma cells through confined space requires membrane tension regulation and mechano-electrical coupling via Plexin-B2

1. Chrystian Junqueira Alves
2. Theodore Hannah
3. Sita Sadia
4. Christy Kolsteeg
5. Angela Dixon
6. Robert J. Wiener
7. Ha Nguyen
8. Murray J. Tipping
9. Júlia Silva Ladeira
10. Paula Fernandes da Costa Franklin
11. Nathália de Paula Dutra de Nigro
12. Rodrigo Alves Dias
13. Priscila V. Zabala Capriles
14. José P. Rodrigues Furtado de Mendonça
15. Paul Slesinger
16. Kevin Costa
17. Hongyan Zou
18. Roland H. Friedel

Reviewed by preLights

Ectopic head regeneration after nervous system ablation in a sea anemone

1. Fatemeh Mazloumi Gavgani
2. Johanna E.M. Kraus
3. Joshua November
4. Layla Al-Shaer
5. Anna Cosima Seybold
6. Benjamin Lerstad
7. Harald Hausen
8. Michael J. Layden
9. Fabian Rentzsch

Reviewed by preLights

Hyaluronic Acid and Emergent Tissue Mechanics Orchestrate Digit Tip Regeneration

1. Byron W.H. Mui
2. Joseph Y. Wong
3. Toni Bray
4. Lauren Connolly
5. Jia Hua Wang
6. Alexander Winkel
7. Pamela G. Robey
8. Kristian Franze
9. Kevin J. Chalut
10. Mekayla A. Storer

Reviewed by preLights

Loss of a morph is associated with asymmetric character release in a radiation of woodland salamanders

1. Brian P. Waldron
2. Maggie M. Hantak
3. Emily F. Watts
4. Josef C. Uyeda
5. Alan R. Lemmon
6. Emily Moriarty Lemmon
7. Robert P. Guralnick
8. David C. Blackburn
9. Shawn R. Kuchta

Reviewed by preLights

Deletion of PIEZO1 in adult cardiomyocytes accelerates cardiac aging and causes premature death

1. Ze-Yan Yu
2. Yang Guo
3. Scott Kesteven
4. Delfine Cheng
5. Hanzhou Lei
6. Jianxin Wu
7. Evelyn Nadar
8. Peter Macdonald
9. Munira Xaymardan
10. Charles D. Cox
11. Michael P. Feneley
12. Boris Martinac

Reviewed by preLights

Decoding the Molecular Language of Proteins with Evola

1. Xibin Zhou
2. Chenchen Han
3. Yingqi Zhang
4. Jin Su
5. Kai Zhuang
6. Shiyu Jiang
7. Zichen Yuan
8. Wei Zheng
9. Fengyuan Dai
10. Yuyang Zhou
11. Yuyang Tao
12. Dan Wu
13. Fajie Yuan

Reviewed by preLights

Conservation and divergence of regulatory architecture in nitrate-responsive plant gene circuits

1. C Bian
2. GS Demirer
3. MT Oz
4. Y Cai
5. SS Witham
6. GA Mason
7. Z Di
8. F Deligne
9. P Zhang
10. R Shen
11. A Gaudinier
12. SM Brady
13. NJ Patron

Reviewed by preLights

Ancestral sequence reconstruction of the Mic60 Mitofilin domain reveals residues supporting respiration in yeast

1. Friederike M. C. Benning
2. Tristan A. Bell
3. Tran H. Nguyen
4. Della Syau
5. Louise B. Connell
6. Margaret Coughlin
7. Anja E. H. Nordstrom
8. Maria Ericsson
9. Corrie J. B. daCosta
10. Luke H. Chao

Reviewed by preLights

A zebrafish circuit for behavioral credit assignment

1. Emanuele Paoli
2. Virginia Palieri
3. Amey Shenoy
4. Ruben Portugues

Reviewed by preLights

Scaly-Tail Organ Enhances Static Stability during Pel’s Scaly-tailed Flying Squirrels’ Arboreal Locomotion

1. Andrew K. Schulz
2. Mrudul Chellapurath
3. Pranav C. Khandelwal
4. SeyedReza Rezaei
5. Stefan Merker
6. Ardian Jusufi

Reviewed by preLights

Tidyplots empowers life scientists with easy code-based data visualization

1. Jan Broder Engler

Reviewed by preLights

Megakaryocytes assemble a three-dimensional cage of extracellular matrix that controls their maturation and anchoring to the vascular niche

1. Claire Masson
2. Cyril Scandola
3. Jean-Yves Rinckel
4. Fabienne Proamer
5. Emily Janus-Bell
6. Fareeha Batool
7. Naël Osmani
8. Jacky G Goetz
9. Léa Mallo
10. Catherine Léon
11. Alicia Bornert
12. Renaud Poincloux
13. Olivier Destaing
14. Alma Mansson
15. Hong Qian
16. Maxime Lehmann
17. Anita Eckly

• Curated by eLife

  eLife Assessment

  The authors provide a thorough investigation of the interaction of megakaryocytes (MK) with their associated extracellular matrix (ECM) during maturation; they provide evidence that the existence of a dense cage-like pericellular structure containing laminin γ1 and α4 and collagen IV is key to fixing the perisinusoidal localization of MK and preventing their premature intravasation. Adhesion of MK to this ECM cage is dependent on integrin beta1 and beta3 expressed by MK. This strong and solid conclusion is based on the use of state-of-the art techniques such as the use of primary murine bone marrow MK cultures, mice lacking ECM receptors, namely integrin beta1 and beta3 null mice, as well as high-resolution 2D and 3D imaging. The study provides valuable insight into the role of cell-matrix interactions in MK maturation and provides an interesting model with practical implications for the fields of hemostasis and thrombosis.

Reviewed by preLights, eLife