Evaluated articles

Chromatin priming and co-factor availability shape lineage response to the neuronal pioneer factor ASCL1 in pluripotency

1. Jethro Lundie-Brown
2. Rosalind Drummond
3. John-Poul Ng-Blichfeldt
4. Roberta Azzarelli
5. Anna Philpott

Reviewed by preLights

Generalization and extinction of learned fear alter primary sensory input to the brain

1. Michelle C. Rosenthal
2. Alper K. Bakir
3. John P. McGann

Reviewed by preLights

Fear conditioning biases olfactory sensory neuron frequencies across generations

1. Clara W Liff
2. Yasmine R Ayman
3. Eliza CB Jaeger
4. Avery Cardeiro
5. Hudson S Lee
6. Alexis Kim
7. Angelica Vina-Abarracin
8. Dianne-Lee KD Ferguson
9. Bianca J Marlin

• Curated by eLife

  eLife Assessment

  This study provides solid evidence that odor fear conditioning biases olfactory sensory neuron receptor choice in mice and that this bias is detectable in the next generation. The authors use rigorous histological and behavioral analyses, including unsupervised behavioral quantification, to support the conclusion that odor-specific sensory representations can be shaped by experience and partially transmitted across generations. While the behavioral effects in offspring are modest and the mechanistic basis of inheritance remains unresolved, the study offers an important and carefully executed contribution to understanding experience-dependent sensory plasticity and its intergenerational consequences.

Reviewed by preLights, eLife

Temporal degradation of PRC2 uncovers specific developmental dependencies

1. Ming-Kang Lee
2. Sebastian D. Mackowiak
3. Daniel Felismino
4. Jeron Venhuizen
5. Maria Walther
6. Alexander Meissner

Reviewed by preLights

The metabolome and proteome of stem cell-derived human primordial germ cells: a multi-omics approach

1. Madalena Vaz Santos
2. Bauke V. Schomakers
3. Marta Llobet Ayala
4. Tara Jamali
5. Michel van Weeghel
6. Ans M. van Pelt
7. Callista L. Mulder
8. Geert Hamer

Reviewed by preLights

“Embryo-eggshell interaction counteracts chiral bias in early Drosophila morphogenesis”

1. Giulia Serafini
2. Maryam Setoudeh
3. Marina B. Cuenca
4. Charlène Brillard
5. Matthias Arzt
6. Pavel Mejstřik
7. Pierre A. Haas
8. Pavel Tomančák

Reviewed by preLights

Cardiac-immune microniches programme macrophage states in the regenerating heart

1. Ehsan Razaghi
2. Selin Tüzüner
3. Trishalee Gungoosingh
4. Kerem Çil
5. Wan Shern Wong
6. Rita Alonaizan
7. Rebecca Richardson
8. Filipa C. Simões

Reviewed by preLights

Gut microbiome changes over the course of multiple sclerosis differentially influence autoimmune neuroinflammation

1. Amélia Sarmento
2. Tommy Regen
3. Daniela Ferro
4. Ángel Ruiz-Moreno
5. Cintya González-Torres
6. Katlynn Carter
7. Arthi Shanmugavadivu
8. Ari Waisman
9. Maria José Sá
10. Carles Ubeda

Reviewed by preLights

Loss of Sun2 ablates nuclear mechanosensing-driven extracellular matrix production and mitigates lung fibrosis

1. Emma Carley
2. Sandra Sandria
3. Xueyan Peng
4. Kerri Davidson
5. Aya Nassereddine
6. Changwan Ryu
7. Rachel Rivera
8. John McGovern
9. Alexander Ghincea
10. C. Patrick Lusk
11. Erica L. Herzog
12. Valerie Horsley
13. Megan C. King

Reviewed by preLights

Prenatal Stress Differentially Shapes Adult Behavior in Male and Female Offspring

1. Erbo Dong
2. Alison Chu
3. Tamar Gur
4. Stephanie M. Gorka

Reviewed by preLights

Experimental evolution of cellular miniaturization reveals a putative mechanism for cell size evolution

1. Garoña Ana
2. Lemos Victoria Morgane
3. Giometto Andrea
4. Fumasoni Marco

Reviewed by preLights

No global collapse of food webs across the Permian–Triassic Mass Extinction

1. Baran Karapunar
2. Tanya Strydom
3. Andrew P. Beckerman
4. Andy Ridgwell
5. Paul B. Wignall
6. Jennifer A. Dunne
7. Crispin T. S. Little
8. Pincelli Hull
9. Catalina Pimiento
10. Alexander M. Dunhill

Reviewed by preLights

Science should be machine-readable

1. A. Sina Booeshaghi
2. Laura Luebbert
3. Lior Pachter

Reviewed by preLights, Arcadia Science

Remote homology and functional genetics unmask deeply preserved Scm3/HJURP orthologs in metazoans

1. Jeremy A. Hollis
2. Jason A. Stonick
3. Irini Topalidou
4. Janet M. Young
5. Cecilia B. Moens
6. Nicolas J. Lehrbach
7. Melody G. Campbell
8. Harmit S. Malik

Reviewed by preLights

UFMylation of Pyruvate Dehydrogenase Regulates Mitochondrial Metabolism

1. Phong T. Nguyen
2. Zheng Wu
3. Dohun Kim
4. Tamaratare Ogu
5. Siyu Yin
6. Varun Sondhi
7. Feng Cai
8. Trevor S. Tippetts
9. Annie Jen
10. Evgenia Shishkova
11. Ling Cai
12. Dennis Dumesnil
13. Margaret Cervantes
14. Hongli Chen
15. Prashant Mishra
16. Joshua J. Coon
17. Gerta Hoxhaj
18. Min Ni
19. Ralph J. DeBerardinis

Reviewed by preLights

Consciously detecting and recognizing a past visual word after its sensory trace is gone

1. Daphné Rimsky Robert
2. Matteo Lisi
3. Kevin Nguy
4. Roxane Jannin
5. Thomas Hardy
6. Nathan Beraud
7. Claire Sergent

Reviewed by preLights

Exogenous Amyloid Sequences: Their Role in Amyloid-Beta Heterotypic Aggregation

1. Jofre Seira Curto
2. Marina Romero Ruiz
3. Genís Pérez Collell
4. Sandra Villegas
5. Maria Rosario Fernandez
6. Natalia Sanchez de Groot

Reviewed by preLights

Liquid-Liquid Phase Separation-mediated formation of amyloid fibrils from DcpS scavenger enzymes

1. Aleksandra Ferenc-Mrozek
2. Maria Winiewska-Szajewska
3. Hanna Nieznańska
4. Wojciech Dzwolak
5. Maciej Łukaszewicz

Reviewed by preLights

Human Assembloid Model of Emergent Neurotropic Enteroviruses

1. Christine E. Peters
2. Jimena Andersen
3. Min-Yin Li
4. Lauren Varanese
5. Mayuri Vijay Thete
6. Se-Jin Yoon
7. Taylor Pio
8. Nicholas Thom
9. Xiaoyu Chen
10. Wenjie Qiao
11. Jan E. Carette
12. Sergiu P. Paşca

Reviewed by preLights

Oxidative stress triggers RNAPII arrest through PARylation and DNA damage

1. Quentin A. Thomas
2. Liyang Wu
3. Emma Lesage
4. Henriette K. M. Iversen
5. David López Martínez
6. Smaragda Kompocholi
7. Haiyue Liu
8. Nicolás Nieto Moreno
9. Lea H. Gregersen

Reviewed by preLights