Evaluated articles

Neanderthal-derived variants shape craniofacial enhancer activity at a human disease locus

1. Kirsty Uttley
2. Hannah J Jüllig
3. Carlo De Angelis
4. Julia MT Auer
5. Ewa Ozga
6. Hemant Bengani
7. Hannah K Long

Reviewed by Review Commons

Tks5 interactome reveals ER-associated machinery translation in invadosomes

1. Léa Normand
2. Benjamin Bonnard
3. Margaux Sala
4. Sylvaine Di-Tommaso
5. Cyril Dourthe
6. Anne-Aurélie Raymond
7. Jean-William Dupuy
8. Luc Mercier
9. Jacky G. Goetz
10. Violaine Moreau
11. Elodie Henriet
12. Frédéric Saltel

Reviewed by Review Commons

Extracellular matrix phenotyping by imaging mass cytometry defines distinct cellular matrix environments associated with allergic airway inflammation

1. J E Parkinson
2. M Ghafoor
3. R J Dodd
4. H E Tompkins
5. M Fergie
6. M Rattray
7. J E Allen
8. T E Sutherland

Reviewed by Review Commons

Regulation of replication timing in Saccharomyces cerevisiae

1. Rosie Berners-Lee
2. Eamonn Gilmore
3. Francisco Berkemeier
4. Michael A. Boemo

Reviewed by Review Commons

A novel SUN1-ALLAN complex coordinates segregation of the bipartite MTOC across the nuclear envelope during rapid closed mitosis in Plasmodium

1. Mohammad Zeeshan
2. Igor Blatov
3. Ryuji Yanase
4. David J. P. Ferguson
5. Sarah L. Pashley
6. Zeinab Chahine
7. Yoshiki Yamaryo Botté
8. Akancha Mishra
9. Baptiste Marché
10. Suhani Bhanvadia
11. Molly Hair
12. Sagar Batra
13. Robert Markus
14. Declan Brady
15. Andrew Bottrill
16. Sue Vaughan
17. Cyrille Y. Botté
18. Karine Le Roch
19. Anthony A. Holder
20. Eelco C. Tromer
21. Rita Tewari

• Curated by eLife

  eLife Assessment

  In Plasmodium male gametocytes, rapid nuclear division occurs with an intact nuclear envelope, requiring precise coordination between nuclear and cytoplasmic events to ensure proper packaging of each nucleus into a developing gamete. This valuable study characterizes two proteins involved in the formation of Plasmodium berghei male gametes. By integrating live-cell imaging, ultrastructural expansion microscopy, and proteomics, this study convincingly identifies SUN1 and its interaction partner ALLAN as crucial nuclear envelope components in male gametogenesis. A role for SUN1 in membrane dynamics and lipid metabolism is less well supported. The results are of interest for general cell biologists working on unusual mitosis pathways.

  [Editors' note: this paper was reviewed by Review Commons.]

Reviewed by eLife, Review Commons

The influence of the pre-membrane and envelope proteins on structure, pathogenicity and tropism of tick-borne encephalitis virus

1. Ebba Rosendal
2. Kyrylo Bisikalo
3. Stefanie M.A. Willekens
4. Marie Lindgren
5. Jiří Holoubek
6. Pavel Svoboda
7. Amanda Lappalainen
8. Ebba Könighofer
9. Ekaterina Mirgorodskaya
10. Rickard Nordén
11. Federico Morini
12. William Rosenbaum
13. Daniel Růžek
14. Ulf Ahlgren
15. Maria Anastasina
16. Andres Merits
17. Sarah J Butcher
18. Emma Nilsson
19. Anna K Överby

Reviewed by Review Commons

Med12 cooperates with multiple differentiation signals to facilitate efficient lineage transitions in embryonic stem cells

1. Max Fernkorn
2. Christian Schröter

Reviewed by Review Commons

Piezo1 balances membrane tension and cortical contractility to stabilize intercellular junctions and maintain epithelial barrier integrity

1. Ahsan Javed
2. Aki Stubb
3. Clémentine Villeneuve
4. Franziska Peters
5. Matthias Rübsam
6. Carien M. Niessen
7. Leah C. Biggs
8. Sara A. Wickström

Reviewed by Review Commons

Δ133p53α and Δ160p53α isoforms of the tumor suppressor protein p53 exert dominant-negative effect primarily by co-aggregation

1. Liuqun Zhao
2. Tanel Punga
3. Suparna Sanyal

Reviewed by Review Commons

Regional heterogeneities of oligodendrocytes determine biased distribution pattern of Ranvier nodes along single axons in sound localization circuit

1. Ryo Egawa
2. Kota Hiraga
3. Ryosuke Matsui
4. Dai Watanabe
5. Hiroshi Kuba

Reviewed by Review Commons

Quantification of Cyclin-CDK dissociation constants in living cells using fluorescence cross-correlation spectroscopy with green and near-infrared fluorescent proteins

1. Aika Toyama
2. Yuhei Goto
3. Yuhei Yamauchi
4. Hironori Sugiyama
5. Yohei Kondo
6. Atsushi Mochizuki
7. Kazuhiro Aoki

Reviewed by Review Commons

A transcription factor toggle switch determines differentiated epidermal cell identities in Hydra

1. Jaroslav Ferenc
2. Marylène Bonvin
3. Panagiotis Papasaikas
4. Jacqueline Ferralli
5. Clara Nuninger
6. Charisios D. Tsiairis

Reviewed by Review Commons

The SUMO activating enzyme subunit, SAE2, contributes SUMO protein bias for mitotic fidelity

1. Alexandra K. Walker
2. Alexander J. Lanz
3. Mohammed Jamshad
4. Alexander J. Garvin
5. Peter Wotherspoon
6. Benjamin F. Cooper
7. Timothy J. Knowles
8. Joanna R. Morris

Reviewed by Review Commons

Embryological cellular origins and hypoxia-mediated mechanisms in PIK3CA -Driven refractory vascular malformations

1. Sota Torii
2. Keiki Nagaharu
3. Nanako Nakanishi
4. Hidehito Usui
5. Yumiko Hori
6. Katsutoshi Hirose
7. Satoru Toyosawa
8. Eiichi Morii
9. Mitsunaga Narushima
10. Yoshiaki Kubota
11. Osamu Nakagawa
12. Kyoko Imanaka-Yoshida
13. Kazuaki Maruyama

Reviewed by Review Commons

SOX2 and NR2F1 coordinate the gene expression program of the early postnatal visual thalamus

1. Linda Serra
2. Anna Nordin
3. Mattias Jonasson
4. Carolina Marenco
5. Francesca Gullo
6. Sergio Ottolenghi
7. Federico Zambelli
8. Michèle Studer
9. Giulio Pavesi
10. Claudio Cantù
11. Silvia K. Nicolis
12. Sara Mercurio

Reviewed by Review Commons

Ribosomal RNA synthesis by RNA polymerase I is regulated by premature termination of transcription

1. Chaïma Azouzi
2. Katrin Schwank
3. Sophie Queille
4. Marta Kwapisz
5. Marion Aguirrebengoa
6. Anthony Henras
7. Simon Lebaron
8. Herbert Tschochner
9. Annick Lesne
10. Frédéric Beckouët
11. Olivier Gadal
12. Christophe Dez

Reviewed by Review Commons

Modularity of the segmentation clock and morphogenesis

1. James E Hammond
2. Ruth E Baker
3. Berta Verd

• Curated by eLife

  eLife Assessment

  This valuable manuscript uses mathematical modeling to address the synchrony of the vertebrate segmentation clock with the developmental processes. The authors use convincing arguments to support the idea that this would allow the evolution of flexible body plans and a variable number of segments. This manuscript could be of interest to developmental biologists and systems biologists.

  [Editors' note: this paper was reviewed by Review Commons.]

Reviewed by eLife, Review Commons

Hormone circuit analysis explains why most HPA drugs fail for mood disorders and predicts the few that work

1. Tomer Milo
2. Shiraz Nir Halber
3. Moriya Raz
4. Avi Mayo
5. Uri Alon

Reviewed by Review Commons

Epigenetic liquid biopsies reveal elevated vascular endothelial cell turnover and erythropoiesis in asymptomatic COVID-19 patients

1. Roni Ben-Ami
2. Netanel Loyfer
3. Eden Cohen
4. Gavriel Fialkoff
5. Israa Sharkia
6. Naama Bogot
7. Danit Kochan
8. George Kalak
9. Amir Jarjoui
10. Chen Chen-Shuali
11. Hava Azulai
12. Hezi Barhoum
13. Nissim Arish
14. Moshe M Greenberger
15. David Vellema
16. Ramzi Kurd
17. Eli Ben Chetrit
18. Davina Bohm
19. Talya Wolak
20. Ahmad Quteineh
21. Gordon Cann
22. Benjamin Glaser
23. Nir Friedman
24. Tommy Kaplan
25. Ruth Shemer
26. Ariel Rokach
27. Yuval Dor

Reviewed by Review Commons, Rapid Reviews Infectious Diseases

Srs2/PARI DNA helicase mediates abscission inhibition in response to chromatin bridges in yeast and human cells

1. Monica Dam
2. Nicola Brownlow
3. Audrey Furst
4. Coralie Spiegelhalter
5. Manuel Mendoza

Reviewed by Review Commons