Evaluated articles

Mammalian MemPrep establishes the lipid composition of ER membranes in HEK293T cells

1. Aamna Jain
2. Alexander von der Malsburg
3. Cynthia Alsayyah
4. Claudia Götz
5. Mohamed Elmofty
6. John Reinhard
7. Per Haberkant
8. Volkhard Helms
9. Joseph H. Lorent
10. Robert Ernst

Reviewed by Review Commons

Spheroid culture remodels mitosis and the proteome in tumor cells

1. Ana Petelinec
2. Claudia Cavarischia-Rega
3. Adrian Perhat
4. Boris Maček
5. Iva M. Tolić

Reviewed by Review Commons

coelsch: Platform-agnostic single-cell analysis of meiotic recombination events

1. Matthew T Parker
2. Samija Amar
3. Jonas Freudigmann
4. Birgit Walkemeier
5. Xiao Dong
6. Victor Solier
7. Magdalena Marek
8. Bruno Huettel
9. Raphael Mercier
10. Korbinian Schneeberger

Reviewed by Review Commons

Exploration of the structural and functional diversity in the metamorphic RfaH subfamily

1. Cyndi Tabilo-Agurto
2. Bastián González-Bustos
3. Javiera Reyes
4. Bing Wang
5. Damaris Palomera
6. Verónica Del Río-Pinilla
7. Camila Neira-Mahuzier
8. Valentina Vera-Sandoval
9. Irina Artsimovitch
10. Pablo Galaz-Davison
11. César A. Ramírez-Sarmiento

Reviewed by Review Commons

Targeting ALC1 can safely expand the therapeutic utility of PARP inhibitors across high-grade serous ovarian cancers

1. Lindsey N. Aubuchon
2. Deanna H. Wong
3. Natasha M. Ramakrishnan
4. Samantha F. Greenberg
5. Rohan Reddy
6. Elena Lomonosova
7. Amanda Compadre
8. Kathleen E. Jackson
9. Danielle Kemper
10. Vrutti Mehta
11. Kellen Zoberi
12. Dineo Khabele
13. Elizabeth L. Christie
14. Mary M. Mullen
15. Priyanka Verma

Reviewed by Review Commons

Lysosomal activation in bladder epithelium enhances intracellular antibiotic clearance of uropathogenic Escherichia coli

1. Kathrin Tomasek
2. Kristina Skurvydaite
3. Gauri Paduthol
4. Allison M. Burns
5. Léa Schlunke
6. Valentin Borgeat
7. Christian Pasquali
8. Mario Romani
9. John D. McKinney

Reviewed by Review Commons

Disruption of small RNAs and mechanistic variation in Segregation Distorter— a sperm-killing drive system in Drosophila melanogaster

1. Logan T. Edvalson
2. Xiaolu Wei
3. Ching-Ho Chang
4. Amanda M. Larracuente

Reviewed by Review Commons

Conserved assembly architecture of the essential herpesvirus packaging accessory factor

1. Elizabeth J. Bailey
2. Swapnil C. Devarkar
3. Renata Szczepaniak
4. Laura M. Meißner
5. Xinyu Chen
6. Chunxiang Wu
7. Sandra K. Weller
8. Yong Xiong
9. Allison L. Didychuk

Reviewed by Review Commons

Hox – Meis -relayed gene regulatory transition underlies cardiopharyngeal neural crest diversification

1. Akiyasu Iwase
2. Yasunobu Uchijima
3. Daiki Seya
4. Mayuko Kida
5. Hiroki Higashiyama
6. Kazuhiro Matsui
7. Akashi Taguchi
8. Yukihiro Harada
9. Yunce Wang
10. Shogo Yamamoto
11. Shiro Fukuda
12. Seitaro Nomura
13. Takahide Kohro
14. Chisa Shukunami
15. Haruhiko Akiyama
16. Masahide Seki
17. Akinori Kanai
18. Yutaka Suzuki
19. Teruhisa Kawamura
20. Osamu Nakagawa
21. Hiroto Katoh
22. Shumpei Ishikawa
23. Youichiro Wada
24. Hiroyuki Aburatani
25. Yukiko Kurihara
26. Sachiko Miyagawa-Tomita
27. Hiroki Kurihara

Reviewed by Review Commons

Genotype-phenotype correlations and de novo induction of cancer stem cells in Wilms tumor initiation

1. N.S. Pop
2. D. Koot
3. C.M. Brouwers
4. M.M. Linssen
5. J.W.C. Claassens
6. C.W.J. Cartlidge
7. D.D. Özdemir
8. K.S. Dolt
9. P. Hohenstein

Reviewed by Review Commons

The neurotrophin DNT-2 regulates cell survival and connectivity via the Toll-2 receptor during visual system development of Drosophila

1. Naser Alshamsi
2. Francisca Rojo-Cortés
3. Bangfu Zhu
4. Samaher Fahy
5. Guiyi Li
6. Anna Lassota
7. Marta Moreira
8. Alicia Hidalgo

Reviewed by Review Commons

TTF2 prevents premature rRNA synthesis during mitotic exit

1. Catarina Pedro
2. Laura Tovini
3. Catarina Peneda
4. Mia Maesano Krapinec
5. Raquel A. Oliveira

Reviewed by Review Commons

Modelling multicellular coordination by bridging cell-cell communication and intracellular regulation through multilayer networks

1. Rémi Trimbour
2. Ricardo O. Ramirez Flores
3. Julio Saez-Rodriguez
4. Laura Cantini

Reviewed by Review Commons

Deubiquitinase USP-14 controls intestinal distension-induced immune activation in Caenorhabditis elegans via Wnt/β-catenin signaling

1. Annesha Ghosh
2. Jogender Singh

Reviewed by Review Commons

Multiple Molecular Pathways to Longevity: Opposing Gene Expression Programs Define Distinct Aging Strategies

1. Zenith D Rudich
2. Jiaxi Guan
3. Aura A Tamez González
4. Grant F Booth
5. Sonja K Soo
6. Ulrich Anglas
7. Meeta Mistry
8. Megan M Senchuk
9. Jeremy M Van Raamsdonk

• Curated by eLife

  eLife Assessment

  This valuable study presents a comparative analysis of the transcriptomic features underlying C. elegans longevity, providing insights into how different changes in gene expression can promote longevity. The authors present solid evidence with analysis and selected functional validation showing that some long-lived animals share common changes while others appear to use opposing strategies. The datasets and analyses contained within and the user-friendly website developed will be of interest to researchers interested in complicated transcriptomic analyses and/or the biology of aging.

  [Editors' note: this paper was reviewed by Review Commons.]

Reviewed by eLife, Review Commons

The co-repressor Groucho limits progression through the early transcription elongation checkpoint in vivo

1. María Lorena Martínez Quiles
2. Barbara H Jennings

Reviewed by Review Commons

The functional maturation of mouse spermatozoa is underpinned by global remodeling of the cellular phosphoproteome

1. David A. Skerrett-Byrne
2. Amanda L. Anderson
3. Raffaele Teperino
4. Nathan D. Burke
5. Elizabeth G. Bromfield
6. Matthew D. Dun
7. Valérie Gailus-Durner
8. Helmut Fuchs
9. Susan Marschall
10. Martin Hrabě de Angelis
11. Sean J. Humphrey
12. Brett Nixon

Reviewed by Review Commons

Integrating computational protein structure predictions and genetic dependencies yields an atlas of human multi-protein complexes (AHMPC)

1. Michael Uckelmann
2. Daniel Alvarez Salmoral
3. Carmen Maiella
4. Onno Bleijerveld
5. Ceri Zwart
6. Eric Marcus
7. Joren Brunekreef
8. Jonas Teuwen
9. Roderick Beijersbergen
10. Anastassis Perrakis

Reviewed by Review Commons

Nucleolar dynamics are determined by the ordered assembly of the ribosome

1. Jessica Sheu-Gruttadauria
2. Xiaowei Yan
3. Nico Stuurman
4. Riley O. Ogrean
5. Sabrina Lin
6. Stephen N. Floor
7. Ronald D. Vale

Reviewed by Review Commons

Systemic RNAi in planarians depends on spread of RNPs from active stem cells

1. Sudheesh Allikka Parambil
2. Karina Ascunce Gonzalez
3. Axel Poulet
4. Levi Cruz
5. Hae-Lim Lee
6. Mariana Witmer
7. Josien C. van Wolfswinkel

Reviewed by Review Commons