Evaluated articles

Brachyury expression levels predict lineage potential and axis-forming ability of in vitro derived neuromesodermal progenitors

1. Anahí Binagui-Casas
2. Anna Granés
3. Alberto Ceccarelli
4. Filip J. Wymeersch
5. Matthew French
6. Rosa Portero
7. Jen Annoh
8. Yali Huang
9. Eleni Karagianni
10. Frederick C.K. Wong
11. A. Sophie Brumm
12. Daniel Lopez Ramajo
13. Minoru Takasato
14. Sally Lowell
15. Osvaldo Chara
16. Valerie Wilson

Reviewed by Review Commons

Differential functions of upstream and intronic HOT regions shape dlg-1 transcription and C. elegans development

1. Cristina Tocchini
2. Fanny Eggeler
3. Palmer Bassett
4. Susan E. Mango

Reviewed by Review Commons

Identification of optimal fluorophores for use in the Drosophila embryo

1. Bernardo Chapa-y-Lazo
2. Thamarailingam Athilingam
3. Prabhat Tiwari
4. Prachi Pathak
5. Shaobo Zhang
6. Sophie Theis
7. Timothy E Saunders

Reviewed by Review Commons

SoxB1-Mediated Chromatin Remodeling Promotes Sensory Neuron Differentiation in Planarians

1. Mallory L. Cathell
2. Mohamad A. Auwal
3. Sarai Alvarez Zepeda
4. Kelly G. Ross
5. Ricardo M. Zayas

Reviewed by Review Commons

Fast MAS NMR Spectroscopy Can Identify G-Quartets and Double-Stranded Structures in Aggregates Formed by GGGGCC RNA Repeats

1. Sara Zager
2. Nataša Medved
3. Mirko Cevec
4. Urša Čerček
5. Boris Rogelj
6. Janez Plavec
7. Jaka Kragelj

Reviewed by Review Commons

Proximity labeling reveals ZFP36L1 as a central hub for post-transcriptional regulation networks in T cells

1. Anouk P. Jurgens
2. Branka Popović
3. Floris P.J. van Alphen
4. Leyma Wardak
5. Antonia Bradarić
6. Sander Engels
7. Carmen van der Zwaan
8. Maartje van den Biggelaar
9. Arie J. Hoogendijk
10. Julien Béthune
11. Monika C. Wolkers

Reviewed by Review Commons

Deciphering chromatin architecture and dynamics in Plasmodium falciparum using the nucDetective pipeline

1. Simon Holzinger
2. Leo Schmutterer
3. Victoria Marie Rothe
4. Maria Theresia Watzlowik
5. Uwe Schwartz
6. Gernot Längst

Reviewed by Review Commons

Genome-wide association study shows developmental robustness control by intestinal maltase via internal environment in Drosophila

1. Soshiro Kashio
2. Izumi Enoki
3. Yuto Yoshinari
4. Takashi Nishimura
5. Masayuki Miura

Reviewed by Review Commons

Specialisation of meiotic kinetochores revealed through a synthetic SAC strategy

1. Lori B Koch
2. Christos Spanos
3. Adele L Marston

• Curated by eLife

  eLife Assessment

  Koch et al. describe a valuable novel methodology, SynSAC, to synchronise cells to analyse meiosis I or meiosis II or mitotic metaphase in budding yeast. The authors present convincing data to validate abscisic acid-induced dimerisation to induce a synthetic spindle assembly checkpoint (SAC) arrest that will be of particular importance to analyse meiosis II. The authors use their approach to determine the composition and phosphorylation of kinetochores from meiotic metaphase I and metaphase II that will be of interest to the broader meiosis research community.

  [Editors' note: this paper was reviewed by Review Commons.]

Reviewed by eLife, Review Commons

Ceramide transfer protein regulates G-protein coupled phospholipase signalling in Drosophila photoreceptors

1. Shirish Mishra
2. Ali Khan
3. Vaisaly R Nath
4. Tejaswini Manoj
5. BG Thejaswini
6. Amruta Naik
7. Ujjaini Dasgupta
8. Padinjat Raghu

Reviewed by Review Commons

Spatial activation of Kinesin-1 by Ensconsin shapes microtubule networks via ncMTOCs recruitment

1. Anne-Marie Berisha
2. Aude Pascal
3. Marine Guelle
4. Clément Bousquet
5. Denis Chrétien
6. Laetitia Bataillé
7. Régis Giet

Reviewed by Review Commons

NASP functions in the cytoplasm to prevent histone H3 aggregation during early embryogenesis

1. Mohit Das
2. Eli Coronado-Chavez
3. Anusha D Bhatt
4. Reyhaneh Tirgar
5. Amanda A Amodeo
6. Jared Nordman

Reviewed by Review Commons

Sterols regulate ciliary membrane dynamics and hedgehog signaling in health and disease

1. Antonin Lamazière
2. Lucie Kozlowski
3. Jesus Ayala-Sanmartin
4. Manal Farhat
5. Nabil Belaid
6. Alexandre Certain
7. Bertrand Isidor
8. Thomas Besnard
9. Germain Trugnan
10. Gregory J Pazour
11. Gaëtan Després
12. Céline Deseille
13. Sarah Moreno
14. Thibaut Eguether

Reviewed by Review Commons

Histone methyltransferase DOT1L differentially affects the development of dendritic cell subsets

1. Rianne G. Bouma
2. Willem-Jan de Leeuw
3. Aru Z. Wang
4. Muddassir Malik
5. Joeke G.C. Stolwijk
6. Veronique A.L. Konijn
7. Anne Mensink
8. Natalie Proost
9. Maarten K. Nijen Twilhaar
10. Tibor van Welsem
11. Negisa Seyed Toutounchi
12. Alsya J. Affandi
13. Jip T. van Dinter
14. Fred van Leeuwen
15. Joke M.M. den Haan

Reviewed by Review Commons

CIP2A Mediates the Recruitment of the SLX4-MUS81-XPF Tri-Nuclease Complex in Mitosis and Protects Against Replication Stress

1. Alice Meroni
2. Annica Pellizzari
3. Andrea Hänel
4. Nathalie Varisco
5. Pascale Brasier-Lutz
6. Isabell Witzel
7. Alessandro A Sartori
8. Manuel Stucki

Reviewed by Review Commons

Patient-specific iPSC models of neural tube defects identify underlying deficiencies in neuroepithelial cell shape regulation and differentiation

1. Ioakeim Ampartzidis
2. Elliott M Thompson
3. Yashica Gupta
4. Andrea Krstevski
5. Nicola Elvassore
6. Eirini Maniou
7. Paolo de Coppi
8. Gabriel L Galea

• Curated by eLife

  eLife Assessment

  The authors used genetic mutations in VANGL2 to study cell morphological changes during differentiation of hPSCs and understand the mechanisms underlying neural tube closure defects. The findings are important as they establish a quantitative, reproducible 2D human iPSC-to-neural-progenitor platform for analyzing cell-shape dynamics during differentiation. The convincing evidence provided, combined with the relative simplicity of the model and its tractability as a patient-specific and reverse genetic platform, make it attractive.

  [Editors' note: this paper was reviewed by Review Commons.]

Reviewed by eLife, Review Commons

NudC moonlights in ribosome biogenesis and homeostasis in Drosophila melanogaster polyploid cells

1. Duoduo Shi
2. Yuko Shimada-Niwa
3. Naoki Okamoto
4. Akira Nakamura
5. Yuya Ohhara
6. Wei Sun
7. Ryusuke Niwa

Reviewed by Review Commons

Ciliary and non-ciliary functions of CEP104 in Xenopus

1. Panagiota Louka
2. Louiza Potamiti
3. Mihalis I. Panayiotidis
4. Paris Skourides

Reviewed by Review Commons

Condensin II collaborates with cohesin to establish and maintain interphase chromosome territories

1. Takao Ono
2. Masatoshi Takagi
3. Hideyuki Tanabe
4. Tomoko Fujita
5. Noriko Saitoh
6. Akatsuki Kimura
7. Tatsuya Hirano

Reviewed by Review Commons

Rab11B is required for binding and entry of recent H3N2, but not H1N1, influenza A isolates

1. Allyson H. Turner
2. Sara A. Jaffrani
3. Hannah C. Kubinski
4. Deborah P. Ajayi
5. Matthew B. Owens
6. Conor D. Fanuele
7. Madeline P. McTigue
8. Cailey L. Appenzeller
9. Addington Bowling
10. Hannah W. Despres
11. Madaline M. Schmidt
12. Dave J. Shirley
13. Jessica W. Crothers
14. Ramiro Barrantes-Reynolds
15. Emily A. Bruce

Reviewed by Review Commons