Evaluated articles

ASPEN: Robust detection of allelic dynamics in single cell RNA-seq

1. Veronika Petrova
2. Muqing Niu
3. Thomas S. Vierbuchen
4. Emily S. Wong

Reviewed by Review Commons

Loss of the alternative calcineurin variant CnAβ1 enhances brown adipocyte differentiation and drives metabolic overactivation through FoxO1 activation

1. Elísabet Bello-Arroyo
2. Blanca Rubio
3. Alfonso Mora
4. Marina López-Olañeta
5. Jesús M. Gómez-Salinero
6. Laura Ramos
7. Carlos G. Sánchez-Cabezudo
8. Emilio Camafeita
9. Lorena Cusso
10. Manuel Desco
11. Nolwenn Joffin
12. Johanne Le Coq
13. Jasminka Boskovic
14. Kathryn A. McGurk
15. James S. Ware
16. Paul J. R. Barton
17. Jesús Vázquez
18. Philipp E. Scherer
19. Guadalupe Sabio
20. María Victoria Gómez-Gaviro
21. Enrique Lara-Pezzi

Reviewed by Review Commons

A Short 63-Nucleotide Element Promotes Efficient circRNA Translation

1. Martina Chiara Biagi
2. Andrea Giuliani
3. Alessia Grandioso
4. Gaia Di Timoteo
5. Irene Bozzoni

Reviewed by Review Commons

A TranSNP in the DDIT4 mRNA can impact its translation efficiency and modulate p53-dependent responses in cancer cells

1. Meriem Hadjer Hamadou
2. Laura Alunno
3. Tecla Venturelli
4. Samuel Valentini
5. Davide Dalfovo
6. Francesca Lorenzini
7. Alessia Mattivi
8. Vincenza Vigorito
9. Glenda Paola Grupelli
10. Alessandro Matte’
11. Pamela Gatto
12. Michael Pancher
13. Chiara Valentini
14. Veronica De Sanctis
15. Roberto Bertorelli
16. Virginie Marcel
17. Emilio Cusanelli
18. Stefano Freddi
19. Giovanni Bertalot
20. Sara Zaccara
21. Marina Mione
22. Luca L. Fava
23. Alessandro Romanel
24. Alberto Inga

Reviewed by Review Commons

Microscopy Nodes: versatile 3D microscopy visualization with Blender

1. Aafke Gros
2. Chandni Bhickta
3. Granita Lokaj
4. Brady Johnston
5. Yannick Schwab
6. Simone Köhler
7. Niccolò Banterle

Reviewed by Review Commons

The 5-methylcytosine DNA glycosylase ROS1 antagonizes parent-of-origin specific DNA methylation in Arabidopsis endosperm

1. Elizabeth A. Hemenway
2. Mary Gehring

Reviewed by Review Commons

Astrocytic connexin43 phosphorylation contributes to seizure susceptibility after mild traumatic brain injury

1. Carmen Muñoz-Ballester
2. Owen Leitzel
3. Samantha Golf
4. Chelsea M Phillips
5. Michael J Zeitz
6. Rahul Pandit
7. Elizabeth Wash
8. Jenna V. Donohue
9. James W. Smyth
10. Samy Lamouille
11. Stefanie Robel

Reviewed by Review Commons

Inverted Assembly of the Lens Within Ocular Organoids Reveals Alternate Paths to Ocular Morphogenesis

1. Elin Stahl
2. Miguel Angel Delgado-Toscano
3. Ishwariya Saravanan
4. Anastasija Paneva
5. Joachim Wittbrodt
6. Lucie Zilova

• Curated by eLife

  eLife Assessment

  This important study demonstrates that ocular organoids can generate both retina and lens through a non-canonical, "inside-out" morphogenetic route. The work is supported by convincing data, with well-designed experiments combining imaging, molecular analysis, and transcriptomics to establish that lens formation in organoids follows conserved molecular programs despite an alternative morphogenesis. These findings expand our understanding of self-organization and developmental plasticity, and will be of broad interest to researchers working on eye development, organoids, and tissue engineering.

  [Editors' note: this paper was reviewed by Review Commons.]

Reviewed by eLife, Review Commons

Organization of the yeast Seipin complex reveals differential recruitment of regulatory proteins

1. Yoel A. Klug
2. Pedro Carvalho

Reviewed by Review Commons

Genome-wide modeling of DNA replication in space and time confirms the emergence of replication specific patterns in vivo in eukaryotes

1. Dario D’Asaro
2. Jean-Michel Arbona
3. Vinciane Piveteau
4. Aurèle Piazza
5. Cédric Vaillant
6. Daniel Jost

Reviewed by Review Commons

Transient hypoxia followed by progressive reoxygenation is required for efficient skeletal muscle repair through Rev-ERBα modulation

1. Marie Quétin
2. Audrey Der Vartanian
3. Christelle Dubois
4. Juliette Berthier
5. Marine Ledoux
6. Stéphanie Michineau
7. Bernadette Drayton-Libotte
8. Athanassia Sotiropoulos
9. Frédéric Relaix
10. Marianne Gervais

Reviewed by Review Commons

Reconfiguration of tumor cells with LCOR transcription factor mRNA nanotherapy to enhance immunotherapy efficacy

1. Gabriel Serra-Mir
2. Elena Haro-Martínez
3. Chiara Cannatà
4. José Ángel Palomeque
5. Sandra Blasco-Benito
6. Anna López-Plana
7. María Sanz-Flores
8. Marc Sabartés
9. Cristina Fornaguera
10. Toni Celià-Terrassa

Reviewed by Review Commons

FAK modulates glioblastoma stem cell energetics via regulation of glycolysis and glutamine oxidation

1. Roza H. A. Masalmeh
2. John C. Dawson
3. Virginia Alvarez Garcia
4. Morwenna T. Muir
5. Roderick N. Carter
6. Giles E. Hardingham
7. Cameron Davies
8. Rosina Graham
9. Alex von Kriegsheim
10. Jair Marques
11. Chinmayi Pednekar
12. Steven M. Pollard
13. Neil O. Carragher
14. Valerie G. Brunton
15. Margaret C. Frame

Reviewed by Review Commons

Fertilization triggers cytosolic functions and P-body recruitment of the RNA-binding protein Mei2 to drive fission yeast zygotic development

1. Ayokunle Araoyinbo
2. Clàudia Salat-Canela
3. Aleksandar Vještica

Reviewed by Review Commons

Systematic identification of Salmonella T6SS effectors uncovers diverse new families and lipid-targeting activities

1. Gianlucca G. Nicastro
2. Stephanie Sibinelli-Sousa
3. Julia T. Hespanhol
4. Thomas W. C. Santos
5. Joseph P. Munoz
6. Rosangela S. Santos
7. Blanca M. Perez-Sepulveda
8. Sayuri Miyamoto
9. L. Aravind
10. Robson F. de Souza
11. Ethel Bayer-Santos

Reviewed by Review Commons

Single-cell analysis of signalling and transcriptional responses to type I interferons

1. Rachel E Rigby
2. Kevin Rue-Albrecht
3. Aleksandr Fedorov
4. David Sims
5. Jan Rehwinkel

Reviewed by Review Commons

Live-cell imaging reveals nutrient-dependent dynamics of ER-mitochondria contact formation via PDZD8

1. Saeko Aoyama-Ishiwatari
2. Koki Nakamura
3. Takahiro Nagao
4. Yusuke Hirabayashi

Reviewed by Review Commons

The heterogeneity of dermal mesenchymal cells reproduced in skin equivalents regulates barrier function and elasticity

1. Shun Kimura
2. Sachiko Sekiya
3. Sawa Yamashiro
4. Tetsutaro Kikuchi
5. Masatoshi Haga
6. Tatsuya Shimizu

Reviewed by Review Commons

Sex-lethal is recruited to chromatin to promote neuronal tRNA synthesis in males through RNA Polymerase III regulation

1. Freya Storer
2. Colin D. McClure
3. Alicia Estacio Gomez
4. Tsz Lam Wong
5. Lucy J. Minkley
6. Tony D. Southall

Reviewed by Review Commons

Inherited CDA-I disease: anemia-associated mutations disrupt CDIN1-Codanin1 complex

1. Martin Stojaspal
2. Tomáš Brom
3. Ivona Nečasová
4. Tomáš Janovič
5. Pavel Veverka
6. Naina Verma
7. Lukáš Uhrík
8. Lenka Hernychova
9. Ctirad Hofr

Reviewed by Review Commons