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Virtual reality reveals fine-scale alterations in behaviour following loss of the ADHD-linked gene adgrl3.1 in zebrafish

This article has 5 authors:
1. Phoebe Reynolds
2. Emily Read
3. Caitlin Daly-East
4. Matthew O Parker
5. Robert Hindges
This article has been curated by 1 group:
- Curated by eLife
  
  eLife Assessment
  
  The study presents valuable findings on early behavioral phenotypes that arise in an ADHD-associated adgrl3.1 mutant zebrafish, using a new behavioral approach with a closed-loop OMR assay. The evidence supporting the claims of the authors is solid; however, the validation of the method and analysis is incomplete and would benefit from more rigorous approaches and validation practices. This work will be of broad interest to developmental biologists and behavioral neuroscientists.
Reviewed by eLife

This article has 5 evaluationsAppears in 1 listLatest version Aug 4, 2026Latest activity Aug 4, 2026
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10.64898/2026.05.25.727443
Flexible brain state engagement predicts cognitive control transdiagnostically

This article has 14 authors:
1. Jean Ye
2. Saloni Mehta
3. Milana Khaitova
4. Jagriti Arora
5. Fuyuze Tokoglu
6. C Alice Hahn
7. Cheryl Lacadie
8. Abigail S Greene
9. Marisa N Spann
10. Gerard Sanacora
11. Scott W Woods
12. Vinod H Srihari
13. R Todd Constable
14. Dustin Scheinost
This article has been curated by 1 group:
- Curated by eLife
  
  eLife Assessment
  
  This valuable paper reports on a measure of flexible brain state engagement, derived from fMRI, as a predictor of cognitive control. One strength of the study is the use of external datasets for validation and replication. The results are solid, although some may benefit from further explanation.
Reviewed by eLife

This article has 3 evaluationsAppears in 1 listLatest version Aug 3, 2026Latest activity Aug 3, 2026

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