Evaluated articles

A lung-on-chip model of early Mycobacterium tuberculosis infection reveals an essential role for alveolar epithelial cells in controlling bacterial growth

1. Vivek V Thacker
2. Neeraj Dhar
3. Kunal Sharma
4. Riccardo Barrile
5. Katia Karalis
6. John D McKinney

Reviewed by eLife, preLights

Massively multiplex single-molecule oligonucleosome footprinting

1. Nour J Abdulhay
2. Colin P McNally
3. Laura J Hsieh
4. Sivakanthan Kasinathan
5. Aidan Keith
6. Laurel S Estes
7. Mehran Karimzadeh
8. Jason G Underwood
9. Hani Goodarzi
10. Geeta J Narlikar
11. Vijay Ramani

Reviewed by eLife

Planarian stem cells sense the identity of the missing pharynx to launch its targeted regeneration

1. Tisha E Bohr
2. Divya A Shiroor
3. Carolyn E Adler

Reviewed by eLife

Superior Colliculus-Projecting GABAergic Retinal Ganglion Cells Mediate Looming-Evoked Flight Response

1. Xue Luo
2. Danrui Cai
3. Kejiong Shen
4. Qinqin Deng
5. Xinlan Lei
6. Sen Jin
7. Wen-Bo Zeng
8. Hua Li
9. Fuqiang Xu
10. Lu Huang
11. Chaoran Ren
12. Min-Hua Luo
13. Ting Xie
14. Yin Shen

Reviewed by eLife

Normative age modelling of cortical thickness in autistic males

1. Richard A. I Bethlehem
2. Jakob Seidlitz
3. Rafael Romero-Garcia
4. Guillaume Dumas
5. Michael V. Lombardo

Reviewed by eLife

mTORC1 induces eukaryotic translation initiation factor 4E interaction with TOS-S6 kinase 1 and its activation

1. Sheikh Tahir Majeed
2. Asiya Batool
3. Rabiya Majeed
4. Nadiem Nazir Bhat
5. Muhammad Afzal Zargar
6. Khurshid Iqbal Andrabi

Reviewed by eLife

Reproducible functional connectivity endophenotype confers high risk of ASD diagnosis in a subset of individuals

1. Sebastian GW. Urchs
2. Hien Duy Nguyen
3. Clara Moreau
4. Christian Dansereau
5. Angela Tam
6. Alan C. Evans
7. Pierre Bellec

Reviewed by eLife

Activity level in left auditory cortex predicts behavioral performance in inhibition tasks in children

1. Sam van Bijnen
2. Lauri Parkkonen
3. Tiina Parviainen

Reviewed by eLife

Disseminating cells in human oral tumours possess an EMT cancer stem cell marker profile that is predictive of metastasis in image-based machine learning

1. Gehad Youssef
2. Luke Gammon
3. Leah Ambler
4. Sophia Lunetto
5. Alice Scemama
6. Hannah Cottom
7. Kim Piper
8. Ian C Mackenzie
9. Michael P Philpott
10. Adrian Biddle

• Curated by eLife

  eLife assessment

  This is a valuable study that convincingly demonstrates that quantification of EpCAM+/CD24+/Vimentin+ cells in the stroma of human oral cancers followed by machine learning algorithms can be used as a prognostic indicator of metastasis.

Reviewed by eLife

Use of signals of positive and negative selection to distinguish cancer genes and passenger genes

1. László Bányai
2. Maria Trexler
3. Krisztina Kerekes
4. Orsolya Csuka
5. László Patthy

Reviewed by eLife

Cell-state transitions and collective cell movement generate an endoderm-like region in gastruloids

1. Ali Hashmi
2. Sham Tlili
3. Pierre Perrin
4. Molly Lowndes
5. Hanna Peradziryi
6. Joshua M Brickman
7. Alfonso Martínez Arias
8. Pierre-François Lenne

Reviewed by eLife

Atoh7-independent specification of retinal ganglion cell identity

1. Justin Brodie-Kommit
2. Brian S. Clark
3. Qing Shi
4. Fion Shiau
5. Dong Won Kim
6. Jennifer Langel
7. Catherine Sheely
8. Philip A Ruzycki
9. Michel Fries
10. Awais Javed
11. Michel Cayouette
12. Tiffany Schmidt
13. Tudor Badea
14. Tom Glaser
15. Haiqing Zhao
16. Joshua Singer
17. Seth Blackshaw
18. Samer Hattar

Reviewed by eLife

Combining agent-based, trait-based and demographic approaches to model coral-community dynamics

1. Bruno Sylvain Carturan
2. Jason Pither
3. Jean-Philippe Maréchal
4. Corey JA Bradshaw
5. Lael Parrott

Reviewed by eLife

Drainage of inflammatory macromolecules from the brain to periphery targets the liver for macrophage infiltration

1. Linlin Yang
2. Jessica A Jiménez
3. Alison M Earley
4. Victoria Hamlin
5. Victoria Kwon
6. Cameron T Dixon
7. Celia E Shiau

Reviewed by eLife

ZBTB18 inhibits SREBP-dependent fatty acid synthesis by counteracting CTBPs and KDM1A/LSD1 activity in glioblastoma

1. R. Ferrarese
2. A. Izzo
3. G. Andrieux
4. S. Lagies
5. J.P. Bartmuss
6. A.P. Masilamani
7. A. Wasilenko
8. D. Osti
9. S. Faletti
10. R. Schulzki
11. Y. Shuai
12. E. Kling
13. V. Ribecco
14. D.H. Heiland
15. S.G. Tholen
16. M. Prinz
17. G. Pelicci
18. B. Kammerer
19. M. Börries
20. M.S. Carro

Reviewed by eLife

N-glycosylation blocks and simultaneously fosters different receptor-ligand binding sites: the chameleonic CD44–hyaluronan interaction

1. Joni Vuorio
2. Jana Škerlová
3. Milan Fábry
4. Václav Veverka
5. Ilpo Vattulainen
6. Pavlína Řezáčová
7. Hector Martinez-Seara

Reviewed by eLife

Specific Neuroligin3–αNeurexin1 signaling regulates GABAergic synaptic function in mouse hippocampus

1. Motokazu Uchigashima
2. Kohtarou Konno
3. Emily Demchak
4. Amy Cheung
5. Takuya Watanabe
6. David G Keener
7. Manabu Abe
8. Timmy Le
9. Kenji Sakimura
10. Toshikuni Sasaoka
11. Takeshi Uemura
12. Yuka Imamura Kawasawa
13. Masahiko Watanabe
14. Kensuke Futai

Reviewed by eLife

Harmful DNA:RNA hybrids are formed in cis and in a Rad51-independent manner

1. Juan Lafuente-Barquero
2. Maria Luisa García-Rubio
3. Marta San Martin-Alonso
4. Belén Gómez-González
5. Andrés Aguilera

Reviewed by eLife

Start codon disruption with CRISPR/Cas9 prevents murine Fuchs’ endothelial corneal dystrophy

1. Hironori Uehara
2. Xiaohui Zhang
3. Felipe Pereira
4. Siddharth Narendran
5. Susie Choi
6. Sai Bhuvanagiri
7. Jinlu Liu
8. Sangeetha Ravi Kumar
9. Austin Bohner
10. Lara Carroll
11. Bonnie Archer
12. Yue Zhang
13. Wei Liu
14. Guangping Gao
15. Jayakrishna Ambati
16. Albert S Jun
17. Balamurali K Ambati

Reviewed by eLife