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  1. Eleven routine clinical features predict COVID-19 severity uncovered by machine learning of longitudinal measurements

    This article has 34 authors:
    1. Kai Zhou
    2. Yaoting Sun
    3. Lu Li
    4. Zelin Zang
    5. Jing Wang
    6. Jun Li
    7. Junbo Liang
    8. Fangfei Zhang
    9. Qiushi Zhang
    10. Weigang Ge
    11. Hao Chen
    12. Xindong Sun
    13. Liang Yue
    14. Xiaomai Wu
    15. Bo Shen
    16. Jiaqin Xu
    17. Hongguo Zhu
    18. Shiyong Chen
    19. Hai Yang
    20. Shigao Huang
    21. Minfei Peng
    22. Dongqing Lv
    23. Chao Zhang
    24. Haihong Zhao
    25. Luxiao Hong
    26. Zhehan Zhou
    27. Haixiao Chen
    28. Xuejun Dong
    29. Chunyu Tu
    30. Minghui Li
    31. Yi Zhu
    32. Baofu Chen
    33. Stan Z. Li
    34. Tiannan Guo

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  2. Stability of SARS-CoV-2 RNA in Nonsupplemented Saliva

    This article has 25 authors:
    1. Isabel M. Ott
    2. Madison S. Strine
    3. Anne E. Watkins
    4. Maikel Boot
    5. Chaney C. Kalinich
    6. Christina A. Harden
    7. Chantal B.F. Vogels
    8. Arnau Casanovas-Massana
    9. Adam J. Moore
    10. M. Catherine Muenker
    11. Maura Nakahata
    12. Maria Tokuyama
    13. Allison Nelson
    14. John Fournier
    15. Santos Bermejo
    16. Melissa Campbell
    17. Rupak Datta
    18. Charles S. Dela Cruz
    19. Shelli F. Farhadian
    20. Albert I. Ko
    21. Akiko Iwasaki
    22. Nathan D. Grubaugh
    23. Craig B. Wilen
    24. Anne L. Wyllie
    25. the Yale IMPACT Research team3

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  3. X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease

    This article has 102 authors:
    1. Sebastian GĂŒnther
    2. Patrick Y. A. Reinke
    3. Yaiza FernĂĄndez-GarcĂ­a
    4. Julia Lieske
    5. Thomas J. Lane
    6. Helen M. Ginn
    7. Faisal H. M. Koua
    8. Christiane Ehrt
    9. Wiebke Ewert
    10. Dominik Oberthuer
    11. Oleksandr Yefanov
    12. Susanne Meier
    13. Kristina Lorenzen
    14. Boris Krichel
    15. Janine-Denise Kopicki
    16. Luca Gelisio
    17. Wolfgang Brehm
    18. Ilona Dunkel
    19. Brandon Seychell
    20. Henry Gieseler
    21. Brenna Norton-Baker
    22. Beatriz Escudero-Pérez
    23. Martin Domaracky
    24. Sofiane Saouane
    25. Alexandra Tolstikova
    26. Thomas A. White
    27. Anna HĂ€nle
    28. Michael Groessler
    29. Holger Fleckenstein
    30. Fabian Trost
    31. Marina Galchenkova
    32. Yaroslav Gevorkov
    33. Chufeng Li
    34. Salah Awel
    35. Ariana Peck
    36. Miriam Barthelmess
    37. Frank SchlĂŒnzen
    38. P. Lourdu Xavier
    39. Nadine Werner
    40. Hina Andaleeb
    41. Najeeb Ullah
    42. Sven Falke
    43. Vasundara Srinivasan
    44. Bruno Alves França
    45. Martin Schwinzer
    46. Hévila Brognaro
    47. Cromarte Rogers
    48. Diogo Melo
    49. Joanna J. Zaitseva-Doyle
    50. Juraj Knoska
    51. Gisel E. Peña-Murillo
    52. Aida Rahmani Mashhour
    53. Vincent Hennicke
    54. Pontus Fischer
    55. Johanna HakanpÀÀ
    56. Jan Meyer
    57. Philip Gribbon
    58. Bernhard Ellinger
    59. Maria Kuzikov
    60. Markus Wolf
    61. Andrea R. Beccari
    62. Gleb Bourenkov
    63. David von Stetten
    64. Guillaume Pompidor
    65. Isabel Bento
    66. Saravanan Panneerselvam
    67. Ivars Karpics
    68. Thomas R. Schneider
    69. Maria Marta Garcia-Alai
    70. Stephan Niebling
    71. Christian GĂŒnther
    72. Christina Schmidt
    73. Robin Schubert
    74. Huijong Han
    75. Juliane Boger
    76. Diana C. F. Monteiro
    77. Linlin Zhang
    78. Xinyuanyuan Sun
    79. Jonathan Pletzer-Zelgert
    80. Jan Wollenhaupt
    81. Christian G. Feiler
    82. Manfred S. Weiss
    83. Eike-Christian Schulz
    84. Pedram Mehrabi
    85. Katarina Karničar
    86. Aleksandra Usenik
    87. Jure Loboda
    88. Henning Tidow
    89. Ashwin Chari
    90. Rolf Hilgenfeld
    91. Charlotte Uetrecht
    92. Russell Cox
    93. Andrea Zaliani
    94. Tobias Beck
    95. Matthias Rarey
    96. Stephan GĂŒnther
    97. Dusan Turk
    98. Winfried Hinrichs
    99. Henry N. Chapman
    100. Arwen R. Pearson
    101. Christian Betzel
    102. Alke Meents

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  4. TCR meta-clonotypes for biomarker discovery with tcrdist3 enabled identification of public, HLA-restricted clusters of SARS-CoV-2 TCRs

    This article has 10 authors:
    1. Koshlan Mayer-Blackwell
    2. Stefan Schattgen
    3. Liel Cohen-Lavi
    4. Jeremy C Crawford
    5. Aisha Souquette
    6. Jessica A Gaevert
    7. Tomer Hertz
    8. Paul G Thomas
    9. Philip Bradley
    10. Andrew Fiore-Gartland
    This article has been curated by 1 group:
    • Curated by eLife

      Evaluation Summary:

      The paper by Mayer-Blackwell et al. builds on the idea that TCRs to the same antigen often share sequence similarities, which they quantify using a bespoke tool TCRdist3. Using this tool they develop the idea of a metaclone, a set of TCRs sharing similarities and potentially recognising the same antigen. They further show that such clonotypes show increased sharing between HLA-related individuals, and explore the use of such clonotypes in characterising antigen-specific immune response across cohorts of individuals. The paper is novel and of interest to a broad range of immunologists interested in repertoire. However, as raised in a series of detailed comments by the reviewers, the message of the paper needs to be sharpened and clearly focused on the development of the metaclone concept (with less emphasis on SARS-Cov-2. The concept of the metaclone itself, which is the main message of the paper, needs to be clarified, and characterised.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #1 and Reviewer #3 agreed to share their names with the authors.)

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  5. SARS-CoV-2 RNA detection using pooling of self-collected samples: Simple protocol may foster asymptomatic surveillance

    This article has 15 authors:
    1. Giselle Ibette Lopez-Lopes
    2. Rita de Cassia Compagnoli Carmona
    3. Valéria Oliveira Silva
    4. Cintia Mayumi Ahagon
    5. Lincoln Spinazola do Prado
    6. Fabiana Pereira dos Santos
    7. Daniela Bernardes Borges da Silva
    8. Katia CorrĂȘa de Oliveira Santos
    9. Margarete Aparecida Benega
    10. Willian Nery Ribeiro
    11. Audrey Cilli
    12. Elaine Monteiro Matsuda
    13. Ana Maria Sardinha Afonso
    14. Maria do Carmo Sampaio Tavares Timenetsky
    15. LuĂ­s Fernando de Macedo BrĂ­gido

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  6. SARS-CoV-2 Seroprevalence Survey Among District Residents Presenting for Serologic Testing at Three Community-Based Test Sites — Washington, DC, July–August, 2020

    This article has 20 authors:
    1. Adrienne Sherman
    2. Jacqueline Reuben
    3. Naomi David
    4. Delores P. Quasie-Woode
    5. Jayleen K. L. Gunn
    6. Carrie F. Nielsen
    7. Patricia Lloyd
    8. Abraham Yohannes
    9. Mary Puckett
    10. Jo Anna Powell
    11. Sarah Leonard
    12. Preetha Iyengar
    13. Fern Johnson-Clarke
    14. Anthony Tran
    15. Matthew McCarroll
    16. Pushker Raj
    17. John Davies-Cole
    18. Jenifer Smith
    19. James A. Ellison
    20. LaQuandra Nesbitt

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  7. Social predictors of food insecurity during the stay-at-home order due to the COVID-19 pandemic in Peru. Results from a cross-sectional web-based survey

    This article has 10 authors:
    1. Jorge L. Cañari-Casaño
    2. Omaira Cochachin-Henostroza
    3. Oliver A. Elorreaga
    4. Gandy Dolores-Maldonado
    5. Anthony Aquino-RamĂ­rez
    6. Sindy Huaman-Gil
    7. Juan P. Giribaldi-Sierralta
    8. Juan Pablo Aparco
    9. Daniel A. Antiporta
    10. Mary E. Penny

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  8. Implications in the quantification of SARS-CoV2 copies in concurrent nasopharyngeal swabs, whole mouth fluid and respiratory droplets

    This article has 12 authors:
    1. Priya Kannian
    2. Bagavad Gita Jayaraman
    3. Swarna Alamelu
    4. Chandra Lavanya
    5. Nagalingeswaran Kumarasamy
    6. Gunaseelan Rajan
    7. Kannan Ranganathan
    8. Pasuvaraj Mahanathi
    9. Veeraraghavan Ashwini
    10. Stephen J. Challacombe
    11. Jennifer Webster-Cyriaque
    12. Newell W. Johnson

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