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  1. Molecular Dynamics Analysis of Fast-Spreading Severe Acute Respiratory Syndrome Coronavirus 2 Variants and Their Effects on the Interaction with Human Angiotensin-Converting Enzyme 2

    This article has 15 authors:
    1. Anacleto Silva de Souza
    2. Vitor Martins de Freitas Amorim
    3. Gabriela D. A. Guardia
    4. Felipe R. C. dos Santos
    5. Filipe F. dos Santos
    6. Robson Francisco de Souza
    7. Guilherme de Araujo Juvenal
    8. Yihua Huang
    9. Pingju Ge
    10. Yinan Jiang
    11. Coco Li
    12. Prajwal Paudel
    13. Henning Ulrich
    14. Pedro A. F. Galante
    15. Cristiane Rodrigues Guzzo

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  2. NHS CHECK: protocol for a cohort study investigating the psychosocial impact of the COVID-19 pandemic on healthcare workers

    This article has 19 authors:
    1. Danielle Lamb
    2. Neil Greenberg
    3. Matthew Hotopf
    4. Rosalind Raine
    5. Reza Razavi
    6. Rupa Bhundia
    7. Hannah Scott
    8. Ewan Carr
    9. Rafael Gafoor
    10. Ioannis Bakolis
    11. Siobhan Hegarty
    12. Emilia Souliou
    13. Anne Marie Rafferty
    14. Rebecca Rhead
    15. Danny Weston
    16. Sam Gnangapragasam
    17. Sally Marlow
    18. Simon Wessely
    19. Sharon A.M. Stevelink

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  3. SARS-CoV-2 nucleocapsid protein adheres to replication organelles before viral assembly at the Golgi/ERGIC and lysosome-mediated egress

    This article has 16 authors:
    1. Katharina M. Scherer
    2. Luca Mascheroni
    3. George W. Carnell
    4. Lucia C. S. Wunderlich
    5. Stanislaw Makarchuk
    6. Marius Brockhoff
    7. Ioanna Mela
    8. Ana Fernandez-Villegas
    9. Max Barysevich
    10. Hazel Stewart
    11. Maria Suau Sans
    12. Charlotte L. George
    13. Jacob R. Lamb
    14. Gabriele S. Kaminski-Schierle
    15. Jonathan L. Heeney
    16. Clemens F. Kaminski

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  4. Exposure route, sex, and age influence disease outcome in a golden Syrian hamster model of SARS-CoV-2 infection

    This article has 29 authors:
    1. Bryan D. Griffin
    2. Bryce M. Warner
    3. Mable Chan
    4. Emelissa J. Mendoza
    5. Nikesh Tailor
    6. Logan Banadyga
    7. Anders Leung
    8. Shihua He
    9. Amrit S. Boese
    10. Jonathan Audet
    11. Wenguang Cao
    12. Estella Moffat
    13. Lauren Garnett
    14. Kevin Tierney
    15. Kaylie N. Tran
    16. Alixandra Albietz
    17. Kathy Manguiat
    18. Geoff Soule
    19. Alexander Bello
    20. Robert Vendramelli
    21. Jessica Lin
    22. Yvon Deschambault
    23. Wenjun Zhu
    24. David Safronetz
    25. Heidi Wood
    26. Samira Mubareka
    27. James E. Strong
    28. Carissa Embury-Hyatt
    29. Darwyn Kobasa

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  5. Cross-Neutralizing Activity Against SARS-CoV-2 Variants in COVID-19 Patients: Comparison of 4 Waves of the Pandemic in Japan

    This article has 15 authors:
    1. Koichi Furukawa
    2. Lidya Handayani Tjan
    3. Silvia Sutandhio
    4. Yukiya Kurahashi
    5. Sachiyo Iwata
    6. Yoshiki Tohma
    7. Shigeru Sano
    8. Sachiko Nakamura
    9. Mitsuhiro Nishimura
    10. Jun Arii
    11. Tatsunori Kiriu
    12. Masatsugu Yamamoto
    13. Tatsuya Nagano
    14. Yoshihiro Nishimura
    15. Yasuko Mori

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  6. Regulatory dissection of the severe COVID-19 risk locus introgressed by Neanderthals

    This article has 13 authors:
    1. Evelyn Jagoda
    2. Davide Marnetto
    3. Gayani Senevirathne
    4. Victoria Gonzalez
    5. Kaushal Baid
    6. Francesco Montinaro
    7. Daniel Richard
    8. Darryl Falzarano
    9. Emmanuelle V LeBlanc
    10. Che C Colpitts
    11. Arinjay Banerjee
    12. Luca Pagani
    13. Terence D Capellini
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      Scientists had previously discovered that humans and neanderthals mated leading to parts of neanderthal DNA becoming part of the human genome today. More recently, it was found that a genetic region, carrying which has been associated with manifestation of severe COVID-19 symptoms, is one that was "introgressed" into humans from neanderthals. This region contains many genetic variants, and this study set out to identify which of these genetic variants may be causally involved in creating severe symptoms in response to COVID-19 infection. The main critiques of the study stem from details of the functional assays to establish the regulatory role of the 4 variants in creating severe COVID-19 symptoms. In particular, the two genes (critical chemokine receptor genes: CCR1 and CCR5) that the authors identify as down-regulated by these variants are actually up-regulated in severe COVID-19 patients, leading to doubt about the role of these variants in changing response to COVID-19 through the regulation of these genes. In that regard, it seems necessary to conduct follow-up experimental and computational analyses to establish the role of these variants in altering CCR1 and CCR5 gene expression.

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  7. COVID- e Vax, an electroporated plasmid DNA vaccine candidate encoding the SARS-CoV-2 Receptor Binding Domain, elicits protective immune responses in animal models of COVID-19

    This article has 55 authors:
    1. Antonella Conforti
    2. Emanuele Marra
    3. Fabio Palombo
    4. Giuseppe Roscilli
    5. Micol Ravà
    6. Valeria Fumagalli
    7. Alessia Muzi
    8. Mariano Maffei
    9. Laura Luberto
    10. Lucia Lione
    11. Erika Salvatori
    12. Mirco Compagnone
    13. Eleonora Pinto
    14. Emiliano Pavoni
    15. Federica Bucci
    16. Grazia Vitagliano
    17. Daniela Stoppoloni
    18. Maria Lucrezia Pacello
    19. Manuela Cappelletti
    20. Fabiana Fosca Ferrara
    21. Emanuela D’Acunto
    22. Valerio Chiarini
    23. Roberto Arriga
    24. Abraham Nyska
    25. Pietro Di Lucia
    26. Davide Marotta
    27. Elisa Bono
    28. Leonardo Giustini
    29. Eleonora Sala
    30. Chiara Perucchini
    31. Jemma Paterson
    32. Kathryn Ann Ryan
    33. Amy-Rose Challis
    34. Giulia Matusali
    35. Francesca Colavita
    36. Gianfranco Caselli
    37. Elena Criscuolo
    38. Nicola Clementi
    39. Nicasio Mancini
    40. Rüdiger Groß
    41. Alina Seidel
    42. Lukas Wettstein
    43. Jan Münch
    44. Lorena Donnici
    45. Matteo Conti
    46. Raffaele De Francesco
    47. Mirela Kuka
    48. Gennaro Ciliberto
    49. Concetta Castilletti
    50. Maria Rosaria Capobianchi
    51. Giuseppe Ippolito
    52. Luca G. Guidotti
    53. Lucio Rovati
    54. Matteo Iannacone
    55. Luigi Aurisicchio

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