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  1. The consequences of a year of the COVID-19 pandemic for the mental health of young adult twins in England and Wales

    This article has 17 authors:
    1. Kaili Rimfeld
    2. Margherita Malanchini
    3. Ryan Arathimos
    4. Agnieszka Gidziela
    5. Oliver Pain
    6. Andrew McMillan
    7. Rachel Ogden
    8. Louise Webster
    9. Amy E. Packer
    10. Nicholas G. Shakeshaft
    11. Kerry L. Schofield
    12. Jean-Baptiste Pingault
    13. Andrea G. Allegrini
    14. Argyris Stringaris
    15. Sophie von Stumm
    16. Cathryn M. Lewis
    17. Robert Plomin

    Reviewed by ScreenIT

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  2. An Assessment of a Rapid SARS-CoV-2 Antigen Test in Bangladesh

    This article has 17 authors:
    1. Zannat Kawser
    2. Mohabbat Hossain
    3. Sara Suliman
    4. Shahin Lockman
    5. Jesse Gitaka
    6. Gama Bandawe
    7. Redwan Rahmat
    8. Imrul Hasan
    9. Abu Bakar Siddik
    10. Mokibul Hassan Afrad
    11. Mohammed Ziaur Rahman
    12. Glenn Miller
    13. David R. Walt
    14. Louise C. Ivers
    15. Regina C. LaRocque
    16. Jason B. Harris
    17. Firdausi Qadri

    Reviewed by ScreenIT

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  3. Randomised controlled trial of intravenous nafamostat mesylate in COVID pneumonitis: Phase 1b/2a experimental study to investigate safety, Pharmacokinetics and Pharmacodynamics

    This article has 49 authors:
    1. Tom M. Quinn
    2. Erin E. Gaughan
    3. Annya Bruce
    4. Jean Antonelli
    5. Richard O'Connor
    6. Feng Li
    7. Sarah McNamara
    8. Oliver Koch
    9. Claire MacKintosh
    10. David Dockrell
    11. Timothy Walsh
    12. Kevin G. Blyth
    13. Colin Church
    14. Jürgen Schwarze
    15. Cecilia Boz
    16. Asta Valanciute
    17. Matthew Burgess
    18. Philip Emanuel
    19. Bethany Mills
    20. Giulia Rinaldi
    21. Gareth Hardisty
    22. Ross Mills
    23. Emily Gwyer Findlay
    24. Sunny Jabbal
    25. Andrew Duncan
    26. Sinéad Plant
    27. Adam D.L. Marshall
    28. Irene Young
    29. Kay Russell
    30. Emma Scholefield
    31. Alastair F. Nimmo
    32. Islom B. Nazarov
    33. Grant C. Churchill
    34. James S.O. McCullagh
    35. Kourosh H. Ebrahimi
    36. Colin Ferrett
    37. Kate Templeton
    38. Steve Rannard
    39. Andrew Owen
    40. Anne Moore
    41. Keith Finlayson
    42. Manu Shankar-Hari
    43. John Norrie
    44. Richard A. Parker
    45. Ahsan R. Akram
    46. Daniel C. Anthony
    47. James W. Dear
    48. Nik Hirani
    49. Kevin Dhaliwal

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  4. Poor neutralization and rapid decay of antibodies to SARS-CoV-2 variants in vaccinated dialysis patients

    This article has 35 authors:
    1. Jessica Bassi
    2. Olivier Giannini
    3. Chiara Silacci-Fregni
    4. Laura Pertusini
    5. Paolo Hitz
    6. Tatiana Terrot
    7. Yves Franzosi
    8. Francesco Muoio
    9. Christian Saliba
    10. Marcel Meury
    11. Exequiel A. Dellota
    12. Josh R. Dillen
    13. Patrick Hernandez
    14. Nadine Czudnochowski
    15. Elisabetta Cameroni
    16. Nicola Beria
    17. Mariangela Ventresca
    18. Alberto Badellino
    19. Soraya Lavorato-Hadjeres
    20. Elisabetta Lecchi
    21. Tecla Bonora
    22. Matteo Mattiolo
    23. Guido Trinci
    24. Daniela Garzoni
    25. Giuseppe Bonforte
    26. Valentina Forni-Ogna
    27. Davide Giunzioni
    28. Lorenzo Berwert
    29. Ravindra K. Gupta
    30. Paolo Ferrari
    31. Alessandro Ceschi
    32. Pietro Cippà
    33. Davide Corti
    34. Antonio Lanzavecchia
    35. Luca Piccoli

    Reviewed by Rapid Reviews Infectious Diseases, ScreenIT

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  5. SARS-CoV-2 RNA and antibody dynamics in a Dutch household study with dense sampling frame

    This article has 26 authors:
    1. Wanda G. H. Han
    2. Arno Swart
    3. Axel Bonačić Marinović.
    4. Dirk Eggink
    5. Johan Reimerink
    6. Lisa A. Wijsman
    7. Bas van der Veer
    8. Sharon van den Brink
    9. Anne-Marie van den Brandt
    10. Sophie van Tol
    11. Gert-Jan Godeke
    12. Fion Brouwer
    13. Marieke Hoogerwerf
    14. The Dutch F. F. X.-COVID-19 Research Group
    15. Arianne B. van Gageldonk-Lafeber
    16. Wim van der Hoek
    17. Susan van den Hof
    18. Adam Meijer
    19. Daphne F. M. Reukers
    20. Chantal Reusken
    21. Inge Roof
    22. Nynke Rots
    23. Daphne F. M. Reukers
    24. Nynke Rots
    25. Chantal Reusken
    26. Adam Meijer

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  6. Seropositivity to Nucleoprotein to detect mild and asymptomatic SARS-CoV-2 infections: A complementary tool to detect breakthrough infections after COVID-19 vaccination?

    This article has 21 authors:
    1. Lotus L. van den Hoogen
    2. Gaby Smits
    3. Cheyenne C.E. van Hagen
    4. Denise Wong
    5. Eric R.A. Vos
    6. Michiel van Boven
    7. Hester E. de Melker
    8. Jeffrey van Vliet
    9. Marjan Kuijer
    10. Linde Woudstra
    11. Alienke J. Wijmenga-Monsuur
    12. Corine H. GeurtsvanKessel
    13. Susanne P. Stoof
    14. Daphne Reukers
    15. Lisa A. Wijsman
    16. Adam Meijer
    17. Chantal B.E.M. Reusken
    18. Nynke Y. Rots
    19. Fiona R.M. van der Klis
    20. Robert S. van Binnendijk
    21. Gerco den Hartog

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  7. Efficacy and Safety of MSC Cell Therapies for Hospitalized Patients with COVID-19: A Systematic Review and Meta-Analysis

    This article has 22 authors:
    1. Wenchun Qu
    2. Zhen Wang
    3. Erica Engelberg-Cook
    4. Dan Yan
    5. Abu Bakar Siddik
    6. Guojun Bu
    7. Julie G Allickson
    8. Eva Kubrova
    9. Arnold I Caplan
    10. Joshua M Hare
    11. Camillo Ricordi
    12. Carl J Pepine
    13. Joanne Kurtzberg
    14. Jorge M Pascual
    15. Jorge M Mallea
    16. Ricardo L Rodriguez
    17. Tarek Nayfeh
    18. Samer Saadi
    19. Ravindra V Durvasula
    20. Elaine M Richards
    21. Keith March
    22. Fred P Sanfilippo

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  8. Comprehensive characterization of the antibody responses to SARS-CoV-2 Spike protein finds additional vaccine-induced epitopes beyond those for mild infection

    This article has 8 authors:
    1. Meghan E Garrett
    2. Jared G Galloway
    3. Caitlin Wolf
    4. Jennifer K Logue
    5. Nicholas Franko
    6. Helen Y Chu
    7. Frederick A Matsen
    8. Julie M Overbaugh
    This article has been curated by 1 group:
    • Curated by eLife

      Evaluation Summary:

      The authors used phage display deep mutational scanning of SARS-CoV-2 Spike protein to profile antibody epitopes outside of the RBD that were recognized in two cohorts of subjects, which together included mRNA vaccinated, SARS-CoV-2 infected with mild or severe COVID-19 and vaccinated with prior infection. Key findings of the study are that severe COVID-19 and vaccinated individuals had higher binding to Spike protein regions NTD, CTD, and SH-H compared to individuals with mild COVID-19, while mild COVID-19 infections had higher binding to FP than vaccinated or severe COVID-19 individuals. They also reported that vaccinated individuals with or without prior infection were not different and that covariates did not appear to impact the antibody recognition profiles. The authors identified potential escape pathways in these epitope regions, some of which differed between vaccination and infection or drifted over time. The authors acknowledge that this approach is limited to linear epitopes and does not include RBD epitopes. However, the study provides novel insight into the major epitope regions targeted by polyclonal antibodies elicited by vaccination vs. infection, as well as potential pathways for the virus to escape recognition.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #2 agreed to share their name with the authors.)

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    This article has 4 evaluationsAppears in 2 listsLatest version Latest activity