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  1. Serial infection with SARS-CoV-2 Omicron BA.1 and BA.2 following three-dose COVID-19 vaccination

    This article has 27 authors:
    1. Hope R. Lapointe
    2. Francis Mwimanzi
    3. Peter K. Cheung
    4. Yurou Sang
    5. Fatima Yaseen
    6. Rebecca Kalikawe
    7. Sneha Datwani
    8. Rachel Waterworth
    9. Gisele Umviligihozo
    10. Siobhan Ennis
    11. Landon Young
    12. Winnie Dong
    13. Don Kirkby
    14. Laura Burns
    15. Victor Leung
    16. Daniel T. Holmes
    17. Mari L. DeMarco
    18. Janet Simons
    19. Nancy Matic
    20. Julio S.G. Montaner
    21. Chanson J. Brumme
    22. Natalie Prystajecky
    23. Masahiro Niikura
    24. Christopher F. Lowe
    25. Marc G. Romney
    26. Mark A. Brockman
    27. Zabrina L. Brumme

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    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  2. Cross-sectional analysis of the humoral response after SARS-CoV-2 vaccination in Sardinian multiple sclerosis patients, a follow-up study

    This article has 29 authors:
    1. Maria Laura Idda
    2. Maristella Pitzalis
    3. Valeria Lodde
    4. Annalisa Loizedda
    5. Jessica Frau
    6. Monia Lobina
    7. Magdalena Zoledziewska
    8. Francesca Virdis
    9. Giuseppe Delogu
    10. Maria Giuseppina Marini
    11. Maura Mingoia
    12. Marco Masala
    13. Lorena Lorefice
    14. Marzia Fronza
    15. Daniele Carmagnini
    16. Elisa Carta
    17. Silvy Pilotto
    18. Paolo Castiglia
    19. Paola Chessa
    20. Sergio Uzzau
    21. Gabriele Farina
    22. Paolo Solla
    23. Maristella Steri
    24. Marcella Devoto
    25. Edoardo Fiorillo
    26. Matteo Floris
    27. Roberto Ignazio Zarbo
    28. Eleonora Cocco
    29. Francesco Cucca

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  3. Structural basis for substrate selection by the SARS-CoV-2 replicase

    This article has 19 authors:
    1. Brandon F. Malone
    2. Jason K. Perry
    3. Paul Dominic B. Olinares
    4. Hery W. Lee
    5. James Chen
    6. Todd C. Appleby
    7. Joy Y. Feng
    8. John P. Bilello
    9. Honkit Ng
    10. Johanna Sotiris
    11. Mark Ebrahim
    12. Eugene Y. D. Chua
    13. Joshua H. Mendez
    14. Ed T. Eng
    15. Robert Landick
    16. Matthias Götte
    17. Brian T. Chait
    18. Elizabeth A. Campbell
    19. Seth A. Darst

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  4. Revealing druggable cryptic pockets in the Nsp1 of SARS-CoV-2 and other β-coronaviruses by simulations and crystallography

    This article has 9 authors:
    1. Alberto Borsatto
    2. Obaeda Akkad
    3. Ioannis Galdadas
    4. Shumeng Ma
    5. Shymaa Damfo
    6. Shozeb Haider
    7. Frank Kozielski
    8. Carolina Estarellas
    9. Francesco Luigi Gervasio
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      SARS-CoV-2 nonstructural protein (Nsp1) has emerged as an attractive target as it plays an important role in modulating the host and viral gene expression. This study describes multiple druggable sites in Nsp1. A 1.1Ã… co-crystal structure of Nsp1 with a fragment, together with computational studies, provides a framework for the rational design of potential antiviral candidates. This important study is methodologically convincing and will be of interest to researchers in the fields of structural virology and rational drug design.

    Reviewed by eLife, ScreenIT

    This article has 6 evaluationsAppears in 3 listsLatest version Latest activity